POGZ report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000724Biological processdouble-strand break repair via homologous recombination
GO_0051301Biological processcell division
GO_0007064Biological processmitotic sister chromatid cohesion
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0051382Biological processkinetochore assembly
GO_0005634Cellular componentnucleus
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005737Cellular componentcytoplasm
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene namePOGZ
Protein namePogo transposable element derived with ZNF domain
Pogo transposable element with ZNF domain (Suppressor of hairy wing homolog 5) (Zinc finger protein 280E) (Zinc finger protein 635)
Pogo transposable element with ZNF domain
NPC intracellular cholesterol transporter 1
SynonymsKIAA0461
Nbla00003
ZNF635
SUHW5
ZNF280E
DescriptionFUNCTION: Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms . Promotes the repair of DNA double-strand breaks through the homologous recombination pathway . .

AccessionsENST00000710270.1
ENST00000368863.6 [Q7Z3K3-5]
ENST00000703169.1
H7C238
ENST00000491586.5 [Q7Z3K3-3]
ENST00000439756.2 [Q7Z3K3-1]
A0A2S0X0P7
Q7Z3K3
ENST00000531094.5 [Q7Z3K3-7]
A0A8V8TQ67
A0A0G2JHK5
ENST00000441516.1
ENST00000594456.1
ENST00000271715.7 [Q7Z3K3-1]
A0A8V8TQQ8
ENST00000703168.1
ENST00000533351.5
E9PJY9
H0YCT3
ENST00000450842.1
E9PIR8
ENST00000439756.1
ENST00000392723.6 [Q7Z3K3-2]
A6PW30
ENST00000533461.5
ENST00000409503.5 [Q7Z3K3-6]
ENST00000529669.1
A0AA34QVU4
A0A2S0X0J5
M0R2X2