REC8 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of REC8 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	98%	1889.42	2596 / 2642	95%	44.69	671 / 705
ovary	92%	713.30	165 / 180	93%	92.94	399 / 430
uterus	99%	1197.79	169 / 170	73%	43.00	337 / 459
adrenal gland	98%	1061.90	252 / 258	70%	51.25	161 / 230
esophagus	91%	690.90	1320 / 1445	56%	8.66	103 / 183
lung	100%	2142.71	578 / 578	45%	10.45	525 / 1155
stomach	100%	2948.55	359 / 359	39%	17.93	112 / 286
thymus	97%	810.98	634 / 653	42%	13.60	252 / 605
bladder	100%	708.90	21 / 21	36%	6.27	183 / 504
intestine	100%	1236.56	965 / 966	34%	8.30	180 / 527
kidney	100%	2096.87	89 / 89	26%	4.60	231 / 901
prostate	100%	1471.03	244 / 245	26%	3.07	129 / 502
breast	96%	704.88	440 / 459	20%	4.40	222 / 1118
pancreas	46%	250.70	150 / 328	70%	14.82	124 / 178
spleen	100%	2743.71	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	8.21	1 / 1
adipose	96%	1201.13	1156 / 1204	0%	0	0 / 0
peripheral blood	94%	1583.48	876 / 929	0%	0	0 / 0
liver	82%	525.02	185 / 226	8%	2.56	31 / 406
lymph node	0%	0	0 / 0	76%	17.84	22 / 29
skin	53%	276.46	950 / 1809	18%	2.53	87 / 472
tonsil	0%	0	0 / 0	64%	17.10	29 / 45
heart	58%	315.26	501 / 861	0%	0	0 / 0
blood vessel	45%	241.24	603 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	6%	0.71	5 / 80
muscle	4%	14.18	29 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007062	Biological process	sister chromatid cohesion
GO_0007130	Biological process	synaptonemal complex assembly
GO_0007283	Biological process	spermatogenesis
GO_0006302	Biological process	double-strand break repair
GO_0007131	Biological process	reciprocal meiotic recombination
GO_0072520	Biological process	seminiferous tubule development
GO_0051177	Biological process	meiotic sister chromatid cohesion
GO_0007141	Biological process	male meiosis I
GO_0001556	Biological process	oocyte maturation
GO_0000724	Biological process	double-strand break repair via homologous recombination
GO_0051321	Biological process	meiotic cell cycle
GO_0009566	Biological process	fertilization
GO_0007286	Biological process	spermatid development
GO_0000776	Cellular component	kinetochore
GO_0030893	Cellular component	meiotic cohesin complex
GO_0000800	Cellular component	lateral element
GO_0001673	Cellular component	male germ cell nucleus
GO_0005634	Cellular component	nucleus
GO_0003682	Molecular function	chromatin binding
GO_0005515	Molecular function	protein binding

Gene name	REC8
Protein name	Meiotic recombination protein REC8 homolog (Cohesin Rec8p) REC8 meiotic recombination protein
Synonyms	REC8L1
Description	FUNCTION: Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity). .
Accessions	ENST00000557806.5 H0YM87 O95072 H0YMV7 ENST00000560501.1 ENST00000642486.2 [O95072-1] ENST00000559797.1 A0A075B715 ENST00000620473.4 [O95072-1] ENST00000611366.5 [O95072-1] ENST00000646765.1 [O95072-1]

REC8 report