TEP1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TEP1 at tissue level.

III. Associated gene sets

GO_0000722Biological processtelomere maintenance via recombination
GO_0006278Biological processRNA-templated DNA biosynthetic process
GO_0016363Cellular componentnuclear matrix
GO_0000781Cellular componentchromosome, telomeric region
GO_1990904Cellular componentribonucleoprotein complex
GO_0005697Cellular componenttelomerase holoenzyme complex
GO_0005737Cellular componentcytoplasm
GO_0070034Molecular functiontelomerase RNA binding
GO_0019899Molecular functionenzyme binding
GO_0005515Molecular functionprotein binding
GO_0003720Molecular functiontelomerase activity
GO_0002039Molecular functionp53 binding
GO_0005524Molecular functionATP binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameTEP1
Protein nameTelomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog)
Alternative protein TEP1
Telomerase associated protein 1
SynonymsTP1
TLP1
DescriptionFUNCTION: Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini . Also a component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport (By similarity). Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity). .

AccessionsENST00000557314.5
H0YJF6
ENST00000262715.10 [Q99973-1]
ENST00000471684.2
L8E7X6
G3V470
Q99973
ENST00000556935.5
G3V5X7
G3V591
H0YJ53
ENST00000555727.5
ENST00000556488.5
ENST00000553365.5
ENST00000553984.1
ENST00000555008.5
H0YIY9
G3V2A4
H0YJP8
H0YIZ2
ENST00000708760.1 [Q99973-1]
ENST00000556549.1