H2BC3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H2BC3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H2BC3 at tissue level.

III. Associated gene sets

GO_0006334Biological processnucleosome assembly
GO_0000781Cellular componentchromosome, telomeric region
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000786Cellular componentnucleosome
GO_0005634Cellular componentnucleus
GO_0030527Molecular functionstructural constituent of chromatin
GO_0046982Molecular functionprotein heterodimerization activity
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameH2BC3
Protein nameHistone H2B type 1-B (H2B-clustered histone 3) (Histone H2B.1) (Histone H2B.f) (H2B/f)
SynonymsHIST1H2BB
H2BFF
DescriptionFUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

AccessionsENST00000615966.2
P33778