Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 11 studies | 26% ± 12% | |
glutamatergic neuron | 10 studies | 43% ± 26% | |
astrocyte | 10 studies | 30% ± 15% | |
oligodendrocyte precursor cell | 9 studies | 29% ± 12% | |
GABAergic neuron | 8 studies | 46% ± 21% | |
oligodendrocyte | 8 studies | 26% ± 8% | |
interneuron | 7 studies | 44% ± 22% | |
ciliated cell | 7 studies | 26% ± 11% | |
neuron | 6 studies | 39% ± 12% | |
epithelial cell | 6 studies | 36% ± 14% | |
microglial cell | 5 studies | 23% ± 5% | |
amacrine cell | 5 studies | 28% ± 10% | |
retina horizontal cell | 5 studies | 25% ± 10% | |
granule cell | 4 studies | 26% ± 5% | |
macrophage | 4 studies | 25% ± 5% | |
retinal ganglion cell | 4 studies | 29% ± 10% | |
retinal bipolar neuron | 4 studies | 19% ± 3% | |
fibroblast | 4 studies | 20% ± 6% | |
endothelial cell of lymphatic vessel | 4 studies | 17% ± 1% | |
GABAergic interneuron | 3 studies | 28% ± 5% | |
retinal cone cell | 3 studies | 22% ± 2% | |
GABAergic amacrine cell | 3 studies | 31% ± 10% | |
OFF-bipolar cell | 3 studies | 25% ± 8% | |
glycinergic amacrine cell | 3 studies | 28% ± 5% | |
retinal rod cell | 3 studies | 19% ± 3% | |
rod bipolar cell | 3 studies | 26% ± 13% | |
type I pneumocyte | 3 studies | 20% ± 5% | |
neural progenitor cell | 3 studies | 25% ± 1% | |
pericyte | 3 studies | 18% ± 2% | |
basal cell | 3 studies | 37% ± 15% | |
goblet cell | 3 studies | 26% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 1584.81 | 459 / 459 | 100% | 14.09 | 1118 / 1118 |
esophagus | 100% | 1330.54 | 1445 / 1445 | 100% | 11.35 | 183 / 183 |
ovary | 100% | 2064.19 | 180 / 180 | 100% | 15.95 | 430 / 430 |
prostate | 100% | 1694.58 | 245 / 245 | 100% | 13.38 | 502 / 502 |
brain | 100% | 2037.55 | 2640 / 2642 | 100% | 16.03 | 705 / 705 |
lung | 100% | 1332.55 | 577 / 578 | 100% | 12.25 | 1155 / 1155 |
stomach | 100% | 1069.20 | 359 / 359 | 100% | 11.11 | 285 / 286 |
bladder | 100% | 1451.48 | 21 / 21 | 100% | 10.52 | 502 / 504 |
uterus | 100% | 1779.07 | 170 / 170 | 100% | 11.22 | 457 / 459 |
thymus | 100% | 1752.90 | 653 / 653 | 100% | 12.72 | 602 / 605 |
kidney | 100% | 1919.51 | 89 / 89 | 99% | 12.87 | 896 / 901 |
pancreas | 100% | 844.05 | 327 / 328 | 99% | 8.91 | 177 / 178 |
intestine | 100% | 1537.24 | 966 / 966 | 99% | 11.41 | 522 / 527 |
liver | 100% | 904.66 | 226 / 226 | 98% | 6.22 | 396 / 406 |
adrenal gland | 100% | 1493.72 | 258 / 258 | 97% | 9.04 | 223 / 230 |
skin | 100% | 1505.74 | 1809 / 1809 | 94% | 9.98 | 444 / 472 |
blood vessel | 100% | 1477.01 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 6.57 | 29 / 29 |
spleen | 100% | 1341.25 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 9.69 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.03 | 1 / 1 |
adipose | 100% | 1381.06 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 1202.54 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 1062.62 | 832 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 85% | 981.10 | 791 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 80% | 4.51 | 64 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051258 | Biological process | protein polymerization |
GO_0006270 | Biological process | DNA replication initiation |
GO_0040038 | Biological process | polar body extrusion after meiotic divisions |
GO_0000808 | Cellular component | origin recognition complex |
GO_0005664 | Cellular component | nuclear origin of replication recognition complex |
GO_0005730 | Cellular component | nucleolus |
GO_0000781 | Cellular component | chromosome, telomeric region |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
GO_0003688 | Molecular function | DNA replication origin binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0000166 | Molecular function | nucleotide binding |
Gene name | ORC4 |
Protein name | Origin recognition complex subunit 4 |
Synonyms | ORC4L |
Description | FUNCTION: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. . |
Accessions | ENST00000536575.5 [O43929-2] ENST00000540442.5 [O43929-3] ENST00000416719.5 C9J2X8 O43929 ENST00000392857.10 [O43929-1] ENST00000264169.6 [O43929-1] C9JGH7 ENST00000457954.5 Q53SE3 ENST00000440042.1 ENST00000535373.5 [O43929-1] |