Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 17 studies | 22% ± 7% | |
plasmacytoid dendritic cell | 16 studies | 41% ± 12% | |
macrophage | 15 studies | 22% ± 7% | |
conventional dendritic cell | 12 studies | 28% ± 13% | |
ciliated cell | 12 studies | 30% ± 9% | |
classical monocyte | 10 studies | 25% ± 8% | |
smooth muscle cell | 10 studies | 21% ± 4% | |
B cell | 9 studies | 19% ± 7% | |
connective tissue cell | 9 studies | 25% ± 9% | |
monocyte | 9 studies | 20% ± 7% | |
basal cell | 9 studies | 28% ± 13% | |
non-classical monocyte | 8 studies | 26% ± 11% | |
myofibroblast cell | 8 studies | 22% ± 5% | |
endothelial cell | 8 studies | 24% ± 9% | |
dendritic cell | 8 studies | 31% ± 17% | |
pericyte | 7 studies | 23% ± 5% | |
epithelial cell | 7 studies | 36% ± 15% | |
myeloid cell | 6 studies | 27% ± 8% | |
natural killer cell | 5 studies | 21% ± 5% | |
microglial cell | 5 studies | 27% ± 7% | |
mast cell | 5 studies | 26% ± 8% | |
neuron | 5 studies | 27% ± 16% | |
hematopoietic precursor cell | 4 studies | 35% ± 12% | |
deuterosomal cell | 4 studies | 30% ± 6% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 20% ± 2% | |
leukocyte | 4 studies | 20% ± 2% | |
memory B cell | 4 studies | 18% ± 2% | |
plasma cell | 4 studies | 25% ± 9% | |
type I pneumocyte | 4 studies | 20% ± 4% | |
endothelial cell of lymphatic vessel | 4 studies | 27% ± 5% | |
glutamatergic neuron | 4 studies | 39% ± 15% | |
oligodendrocyte precursor cell | 4 studies | 22% ± 3% | |
mononuclear phagocyte | 3 studies | 31% ± 16% | |
neural crest cell | 3 studies | 22% ± 2% | |
precursor B cell | 3 studies | 21% ± 3% | |
naive B cell | 3 studies | 21% ± 5% | |
abnormal cell | 3 studies | 30% ± 7% | |
endothelial cell of vascular tree | 3 studies | 19% ± 1% | |
GABAergic neuron | 3 studies | 32% ± 7% | |
granulocyte monocyte progenitor cell | 3 studies | 34% ± 15% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 40% ± 17% | |
goblet cell | 3 studies | 34% ± 18% | |
oligodendrocyte | 3 studies | 16% ± 1% | |
hematopoietic stem cell | 3 studies | 19% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2575.06 | 1445 / 1445 | 100% | 21.44 | 183 / 183 |
lung | 100% | 2714.28 | 578 / 578 | 100% | 26.29 | 1155 / 1155 |
ovary | 100% | 3547.97 | 180 / 180 | 100% | 30.86 | 430 / 430 |
pancreas | 100% | 1574.88 | 328 / 328 | 100% | 26.68 | 178 / 178 |
prostate | 100% | 3896.04 | 245 / 245 | 100% | 39.60 | 502 / 502 |
skin | 100% | 4087.03 | 1809 / 1809 | 100% | 46.98 | 472 / 472 |
stomach | 100% | 2126.26 | 359 / 359 | 100% | 20.29 | 286 / 286 |
thymus | 100% | 3337.49 | 653 / 653 | 100% | 31.92 | 605 / 605 |
uterus | 100% | 3523.18 | 170 / 170 | 100% | 32.65 | 459 / 459 |
kidney | 100% | 2687.92 | 89 / 89 | 100% | 23.61 | 900 / 901 |
brain | 100% | 2321.95 | 2638 / 2642 | 100% | 36.34 | 705 / 705 |
breast | 100% | 3430.98 | 459 / 459 | 100% | 32.39 | 1116 / 1118 |
liver | 100% | 1307.27 | 226 / 226 | 100% | 18.77 | 405 / 406 |
intestine | 100% | 2574.16 | 966 / 966 | 100% | 20.67 | 525 / 527 |
bladder | 100% | 2698.19 | 21 / 21 | 100% | 27.30 | 502 / 504 |
adrenal gland | 100% | 2926.90 | 258 / 258 | 99% | 27.40 | 228 / 230 |
adipose | 100% | 2915.12 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 41.66 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 36.16 | 29 / 29 |
muscle | 100% | 2778.16 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2853.56 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 27.90 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.65 | 1 / 1 |
blood vessel | 100% | 3033.34 | 1331 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 3897.26 | 858 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 1525.85 | 896 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007584 | Biological process | response to nutrient |
GO_0090656 | Biological process | t-circle formation |
GO_0006303 | Biological process | double-strand break repair via nonhomologous end joining |
GO_0006281 | Biological process | DNA repair |
GO_0007283 | Biological process | spermatogenesis |
GO_0048568 | Biological process | embryonic organ development |
GO_0036297 | Biological process | interstrand cross-link repair |
GO_0008283 | Biological process | cell population proliferation |
GO_0006949 | Biological process | syncytium formation |
GO_0010165 | Biological process | response to X-ray |
GO_0009650 | Biological process | UV protection |
GO_0032205 | Biological process | negative regulation of telomere maintenance |
GO_0008340 | Biological process | determination of adult lifespan |
GO_0048009 | Biological process | insulin-like growth factor receptor signaling pathway |
GO_0006289 | Biological process | nucleotide-excision repair |
GO_0035902 | Biological process | response to immobilization stress |
GO_0070914 | Biological process | UV-damage excision repair |
GO_0035264 | Biological process | multicellular organism growth |
GO_0090399 | Biological process | replicative senescence |
GO_0000720 | Biological process | pyrimidine dimer repair by nucleotide-excision repair |
GO_0046686 | Biological process | response to cadmium ion |
GO_0035166 | Biological process | post-embryonic hemopoiesis |
GO_0060261 | Biological process | positive regulation of transcription initiation by RNA polymerase II |
GO_0009744 | Biological process | response to sucrose |
GO_1905765 | Biological process | negative regulation of protection from non-homologous end joining at telomere |
GO_0008584 | Biological process | male gonad development |
GO_0045190 | Biological process | isotype switching |
GO_0061819 | Biological process | telomeric DNA-containing double minutes formation |
GO_0006312 | Biological process | mitotic recombination |
GO_0006979 | Biological process | response to oxidative stress |
GO_0048477 | Biological process | oogenesis |
GO_1904431 | Biological process | positive regulation of t-circle formation |
GO_0000110 | Cellular component | nucleotide-excision repair factor 1 complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0070522 | Cellular component | ERCC4-ERCC1 complex |
GO_0000109 | Cellular component | nucleotide-excision repair complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0000781 | Cellular component | chromosome, telomeric region |
GO_0003677 | Molecular function | DNA binding |
GO_1990841 | Molecular function | promoter-specific chromatin binding |
GO_0003697 | Molecular function | single-stranded DNA binding |
GO_0001094 | Molecular function | TFIID-class transcription factor complex binding |
GO_1990599 | Molecular function | 3' overhang single-stranded DNA endodeoxyribonuclease activity |
GO_0000014 | Molecular function | single-stranded DNA endodeoxyribonuclease activity |
GO_0005515 | Molecular function | protein binding |
GO_0003684 | Molecular function | damaged DNA binding |
Gene name | ERCC1 |
Protein name | ERCC1 protein ERCC excision repair 1, endonuclease non-catalytic subunit Excision repair protein DNA excision repair protein ERCC-1 |
Synonyms | |
Description | FUNCTION: [Isoform 1]: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. .; FUNCTION: [Isoform 2]: Not functional in the nucleotide excision repair pathway. .; FUNCTION: [Isoform 3]: Not functional in the nucleotide excision repair pathway. .; FUNCTION: [Isoform 4]: Not functional in the nucleotide excision repair pathway. . |
Accessions | ENST00000589214.1 Q8WWH8 ENST00000592444.5 ENST00000710953.1 K7ER60 ENST00000587888.5 A0AA34QVL1 ENST00000590701.5 ENST00000592083.5 K7EK97 K7EJL2 Q16456 K7ER89 ENST00000592023.5 ENST00000591636.5 K7EP14 ENST00000340192.11 [P07992-2] P07992 ENST00000589381.5 K7EMT9 ENST00000300853.8 [P07992-1] ENST00000589165.5 [P07992-1] K7EJW9 K7ES46 ENST00000423698.6 [P07992-4] ENST00000013807.9 [P07992-3] |