TOX4 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	21 studies	21% ± 6%	Explore
endothelial cell	18 studies	23% ± 6%	Explore
regulatory T cell	13 studies	20% ± 3%	Explore
T cell	12 studies	18% ± 3%	Explore
CD8-positive, alpha-beta T cell	11 studies	22% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	21% ± 3%	Explore
fibroblast	10 studies	21% ± 6%	Explore
pericyte	10 studies	18% ± 3%	Explore
gamma-delta T cell	10 studies	24% ± 11%	Explore
plasmacytoid dendritic cell	10 studies	25% ± 7%	Explore
B cell	9 studies	21% ± 5%	Explore
smooth muscle cell	9 studies	19% ± 2%	Explore
classical monocyte	9 studies	24% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	23% ± 4%	Explore
CD4-positive, alpha-beta T cell	8 studies	23% ± 7%	Explore
endothelial cell of vascular tree	8 studies	17% ± 1%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	20% ± 3%	Explore
mature NK T cell	7 studies	19% ± 3%	Explore
mucosal invariant T cell	7 studies	20% ± 2%	Explore
mast cell	6 studies	23% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	24% ± 5%	Explore
naive B cell	6 studies	20% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	21% ± 5%	Explore
non-classical monocyte	6 studies	28% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	25% ± 7%	Explore
monocyte	5 studies	18% ± 2%	Explore
epithelial cell	5 studies	42% ± 16%	Explore
astrocyte	5 studies	23% ± 5%	Explore
T follicular helper cell	5 studies	18% ± 2%	Explore
basal cell	5 studies	29% ± 13%	Explore
memory B cell	5 studies	17% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	20% ± 3%	Explore
myofibroblast cell	4 studies	23% ± 7%	Explore
ciliated cell	4 studies	35% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	24% ± 9%	Explore
innate lymphoid cell	4 studies	19% ± 2%	Explore
macrophage	4 studies	21% ± 4%	Explore
type I pneumocyte	4 studies	23% ± 4%	Explore
goblet cell	4 studies	19% ± 2%	Explore
oligodendrocyte	4 studies	20% ± 2%	Explore
endothelial cell of lymphatic vessel	3 studies	22% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	20% ± 0%	Explore
leukocyte	3 studies	21% ± 3%	Explore
conventional dendritic cell	3 studies	33% ± 11%	Explore
exhausted T cell	3 studies	26% ± 12%	Explore
plasmablast	3 studies	34% ± 13%	Explore
capillary endothelial cell	3 studies	17% ± 1%	Explore
retinal bipolar neuron	3 studies	26% ± 6%	Explore
myeloid cell	3 studies	33% ± 3%	Explore
precursor B cell	3 studies	24% ± 9%	Explore
abnormal cell	3 studies	26% ± 11%	Explore
oligodendrocyte precursor cell	3 studies	32% ± 10%	Explore
enteroendocrine cell	3 studies	20% ± 6%	Explore
intestinal crypt stem cell	3 studies	17% ± 1%	Explore
group 3 innate lymphoid cell	3 studies	25% ± 11%	Explore
transit amplifying cell	3 studies	20% ± 6%	Explore
glutamatergic neuron	3 studies	37% ± 12%	Explore
interneuron	3 studies	32% ± 13%	Explore
neuron	3 studies	27% ± 7%	Explore
double negative thymocyte	3 studies	31% ± 12%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	23% ± 8%	Explore
lung	6 studies	26% ± 11%	Explore
brain	5 studies	29% ± 8%	Explore
eye	4 studies	20% ± 4%	Explore
intestine	4 studies	21% ± 5%	Explore
liver	3 studies	25% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4898.09	1445 / 1445	100%	31.70	183 / 183
intestine	100%	4596.85	966 / 966	100%	28.22	527 / 527
lung	100%	4060.00	578 / 578	100%	36.12	1155 / 1155
ovary	100%	3807.48	180 / 180	100%	33.55	430 / 430
stomach	100%	3714.81	359 / 359	100%	26.48	286 / 286
uterus	100%	4082.15	170 / 170	100%	35.22	459 / 459
thymus	100%	4183.18	653 / 653	100%	36.38	604 / 605
breast	100%	4426.38	459 / 459	100%	44.28	1116 / 1118
prostate	100%	3875.10	245 / 245	100%	35.81	501 / 502
bladder	100%	4558.19	21 / 21	100%	29.67	502 / 504
brain	100%	3281.79	2634 / 2642	100%	36.04	704 / 705
skin	100%	5395.10	1809 / 1809	99%	35.06	469 / 472
pancreas	100%	2383.59	327 / 328	99%	28.88	177 / 178
liver	100%	2153.30	226 / 226	99%	19.21	401 / 406
kidney	100%	3319.28	89 / 89	98%	26.73	884 / 901
adrenal gland	100%	3816.22	258 / 258	96%	25.62	220 / 230
adipose	100%	4511.11	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4795.95	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	31.80	29 / 29
muscle	100%	6633.06	803 / 803	0%	0	0 / 0
spleen	100%	3752.63	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	38.60	45 / 45
ureter	0%	0	0 / 0	100%	8.30	1 / 1
peripheral blood	99%	4334.39	922 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	99%	27.27	79 / 80
heart	98%	3353.88	841 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0072357	Cellular component	PTW/PP1 phosphatase complex
GO_0000781	Cellular component	chromosome, telomeric region
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0031490	Molecular function	chromatin DNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	TOX4
Protein name	TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1) TOX high mobility group box family member 4
Synonyms	C14orf92 KIAA0737
Description	FUNCTION: Transcription factor that modulates cell fate reprogramming from the somatic state to the pluripotent and neuronal fate (By similarity). Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase . In liver, controls the expression of hormone-regulated gluconeogenic genes such as G6PC1 and PCK1. This regulation is independent of the insulin receptor activation (By similarity). .
Accessions	ENST00000613569.4 [O94842-1] A0A669KA85 F8WBE8 ENST00000416256.5 ENST00000455393.5 O94842 C9J919 ENST00000448790.7 [O94842-1] C9JNL1 F8WC04 F8WCL8 ENST00000447695.5 ENST00000673911.1 A0A669KB71 ENST00000455138.1 ENST00000673643.1 ENST00000457430.2

TOX4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review