Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 34 studies | 30% ± 13% | |
ciliated cell | 19 studies | 35% ± 17% | |
fibroblast | 17 studies | 21% ± 6% | |
smooth muscle cell | 17 studies | 21% ± 5% | |
pericyte | 13 studies | 23% ± 7% | |
endothelial cell of lymphatic vessel | 12 studies | 24% ± 10% | |
astrocyte | 11 studies | 30% ± 15% | |
glutamatergic neuron | 10 studies | 41% ± 24% | |
capillary endothelial cell | 9 studies | 22% ± 6% | |
basal cell | 9 studies | 28% ± 15% | |
endothelial cell of vascular tree | 9 studies | 23% ± 12% | |
oligodendrocyte precursor cell | 8 studies | 29% ± 12% | |
epithelial cell | 8 studies | 39% ± 21% | |
vein endothelial cell | 8 studies | 26% ± 16% | |
type I pneumocyte | 7 studies | 21% ± 5% | |
interneuron | 7 studies | 39% ± 21% | |
adipocyte | 7 studies | 23% ± 5% | |
GABAergic neuron | 7 studies | 42% ± 20% | |
oligodendrocyte | 7 studies | 27% ± 7% | |
endothelial cell of artery | 6 studies | 21% ± 3% | |
myofibroblast cell | 6 studies | 23% ± 7% | |
goblet cell | 6 studies | 30% ± 22% | |
secretory cell | 5 studies | 22% ± 5% | |
retina horizontal cell | 5 studies | 36% ± 8% | |
cardiac muscle cell | 5 studies | 20% ± 2% | |
deuterosomal cell | 4 studies | 23% ± 7% | |
squamous epithelial cell | 4 studies | 46% ± 17% | |
amacrine cell | 4 studies | 21% ± 3% | |
neuron | 4 studies | 39% ± 4% | |
ionocyte | 3 studies | 33% ± 3% | |
type B pancreatic cell | 3 studies | 31% ± 8% | |
glomerular endothelial cell | 3 studies | 22% ± 3% | |
retinal bipolar neuron | 3 studies | 17% ± 2% | |
GABAergic interneuron | 3 studies | 25% ± 9% | |
granule cell | 3 studies | 30% ± 7% | |
macrophage | 3 studies | 26% ± 8% | |
microglial cell | 3 studies | 24% ± 7% | |
retinal ganglion cell | 3 studies | 21% ± 3% | |
club cell | 3 studies | 22% ± 1% | |
retinal cone cell | 3 studies | 21% ± 3% | |
lymphocyte | 3 studies | 19% ± 2% | |
respiratory goblet cell | 3 studies | 21% ± 5% | |
pancreatic A cell | 3 studies | 27% ± 8% | |
abnormal cell | 3 studies | 26% ± 7% | |
ependymal cell | 3 studies | 41% ± 11% | |
transit amplifying cell | 3 studies | 37% ± 25% | |
mesothelial cell | 3 studies | 31% ± 11% | |
connective tissue cell | 3 studies | 24% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 12833.68 | 1445 / 1445 | 100% | 47.44 | 183 / 183 |
intestine | 100% | 12748.97 | 966 / 966 | 100% | 35.05 | 527 / 527 |
breast | 100% | 16018.76 | 459 / 459 | 100% | 37.25 | 1117 / 1118 |
lung | 100% | 11056.79 | 576 / 578 | 100% | 42.86 | 1155 / 1155 |
bladder | 100% | 10308.62 | 21 / 21 | 100% | 35.40 | 502 / 504 |
uterus | 100% | 21587.08 | 170 / 170 | 100% | 41.11 | 457 / 459 |
prostate | 100% | 10560.10 | 245 / 245 | 99% | 31.59 | 499 / 502 |
stomach | 100% | 9522.43 | 359 / 359 | 99% | 33.21 | 284 / 286 |
thymus | 100% | 12125.37 | 653 / 653 | 99% | 34.34 | 600 / 605 |
skin | 100% | 13838.72 | 1809 / 1809 | 99% | 35.84 | 468 / 472 |
kidney | 100% | 8727.81 | 89 / 89 | 99% | 37.94 | 893 / 901 |
ovary | 100% | 18384.93 | 180 / 180 | 99% | 28.20 | 426 / 430 |
adrenal gland | 100% | 6333.75 | 258 / 258 | 98% | 29.79 | 226 / 230 |
pancreas | 99% | 5111.79 | 324 / 328 | 99% | 40.26 | 177 / 178 |
brain | 97% | 7729.49 | 2550 / 2642 | 100% | 32.39 | 704 / 705 |
liver | 97% | 3942.11 | 220 / 226 | 94% | 17.92 | 381 / 406 |
adipose | 100% | 16421.60 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 15099.03 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 11495.79 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 10186.28 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 32.21 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.89 | 1 / 1 |
heart | 100% | 8922.80 | 859 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 93% | 22.08 | 74 / 80 |
lymph node | 0% | 0 | 0 / 0 | 79% | 11.32 | 23 / 29 |
peripheral blood | 22% | 1829.12 | 209 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0070197 | Biological process | meiotic attachment of telomere to nuclear envelope |
GO_0007283 | Biological process | spermatogenesis |
GO_0007129 | Biological process | homologous chromosome pairing at meiosis |
GO_0051642 | Biological process | centrosome localization |
GO_0090292 | Biological process | nuclear matrix anchoring at nuclear membrane |
GO_0009612 | Biological process | response to mechanical stimulus |
GO_0001503 | Biological process | ossification |
GO_0021817 | Biological process | nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration |
GO_0005637 | Cellular component | nuclear inner membrane |
GO_0005635 | Cellular component | nuclear envelope |
GO_0034993 | Cellular component | meiotic nuclear membrane microtubule tethering complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0000781 | Cellular component | chromosome, telomeric region |
GO_0031965 | Cellular component | nuclear membrane |
GO_0043495 | Molecular function | protein-membrane adaptor activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005521 | Molecular function | lamin binding |
GO_0005515 | Molecular function | protein binding |
GO_0140444 | Molecular function | cytoskeleton-nuclear membrane anchor activity |
Gene name | SUN1 |
Protein name | SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1) Sad1 and UNC84 domain containing 1 SUN domain-containing protein 1 |
Synonyms | KIAA0810 UNC84A |
Description | FUNCTION: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton . The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity). Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration (By similarity). Involved in telomere attachment to nuclear envelope in the prophase of meiosis implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly (By similarity). Required for gametogenesis and involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis (By similarity). Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity). Required for efficient localization of SYNE4 in the nuclear envelope (By similarity). May be involved in nuclear remodeling during sperm head formation in spermatogenesis (By similarity). May play a role in DNA repair by suppressing non-homologous end joining repair to facilitate the repair of DNA cross-links . . |
Accessions | A0A146IHP0 ENST00000425407.6 [O94901-5] ENST00000429178.5 ENST00000440380.5 H0Y742 ENST00000452783.6 ENST00000424128.5 ENST00000421580.5 ENST00000433212.5 H0Y6N5 E9PHI4 C9JR15 ENST00000419312.5 C9JS54 ENST00000457378.6 [O94901-7] C9JJU6 ENST00000435699.5 ENST00000439679.5 C9JK55 C9K051 H7C2K3 ENST00000450881.5 ENST00000457861.1 ENST00000403868.5 [O94901-2] H7C3X3 A0A8I5G938 ENST00000401592.6 [O94901-8] ENST00000405266.5 O94901 ENST00000457598.5 H7C019 ENST00000389574.7 [O94901-5] |