SMTNL1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SMTNL1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SMTNL1 at tissue level.

III. Associated gene sets

GO_0045907Biological processpositive regulation of vasoconstriction
GO_0014823Biological processresponse to activity
GO_0030036Biological processactin cytoskeleton organization
GO_0048644Biological processmuscle organ morphogenesis
GO_0009410Biological processresponse to xenobiotic stimulus
GO_0042310Biological processvasoconstriction
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0031941Cellular componentfilamentous actin
GO_0005815Cellular componentmicrotubule organizing center
GO_0043292Cellular componentcontractile muscle fiber
GO_0031674Cellular componentI band
GO_0005737Cellular componentcytoplasm
GO_0031430Cellular componentM band
GO_0005634Cellular componentnucleus
GO_0005523Molecular functiontropomyosin binding
GO_0051401Molecular functionCH domain binding
GO_0008157Molecular functionprotein phosphatase 1 binding
GO_0005516Molecular functioncalmodulin binding
GO_0097718Molecular functiondisordered domain specific binding

IV. Literature review

[source]
Gene nameSMTNL1
Protein nameSmoothelin-like protein 1
Synonyms
DescriptionFUNCTION: Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). .

AccessionsA8MU46
ENST00000527972.6