Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 12 studies | 26% ± 12% | |
| pro-B cell | 5 studies | 42% ± 13% | |
| hematopoietic precursor cell | 4 studies | 38% ± 10% | |
| deuterosomal cell | 4 studies | 32% ± 13% | |
| precursor B cell | 4 studies | 31% ± 9% | |
| hematopoietic stem cell | 3 studies | 37% ± 14% | |
| epithelial cell | 3 studies | 27% ± 6% | |
| intestinal crypt stem cell | 3 studies | 30% ± 9% |
Insufficient scRNA-seq data for expression of MYB at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 67% | 1702.86 | 309 / 459 | 91% | 59.35 | 1014 / 1118 |
| intestine | 63% | 1134.82 | 612 / 966 | 89% | 39.97 | 470 / 527 |
| prostate | 92% | 250.96 | 226 / 245 | 44% | 4.25 | 221 / 502 |
| stomach | 52% | 66.39 | 185 / 359 | 84% | 31.13 | 239 / 286 |
| lung | 94% | 315.42 | 543 / 578 | 36% | 7.10 | 411 / 1155 |
| esophagus | 57% | 182.41 | 821 / 1445 | 48% | 13.92 | 88 / 183 |
| bladder | 52% | 74.48 | 11 / 21 | 45% | 14.24 | 225 / 504 |
| spleen | 88% | 198.37 | 212 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 81% | 763.06 | 751 / 929 | 0% | 0 | 0 / 0 |
| skin | 75% | 397.52 | 1350 / 1809 | 3% | 0.26 | 12 / 472 |
| uterus | 26% | 60.68 | 45 / 170 | 40% | 5.92 | 184 / 459 |
| lymph node | 0% | 0 | 0 / 0 | 66% | 6.20 | 19 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 60% | 10.70 | 27 / 45 |
| ovary | 3% | 2.83 | 6 / 180 | 45% | 5.21 | 194 / 430 |
| adrenal gland | 43% | 82.18 | 112 / 258 | 1% | 0.18 | 3 / 230 |
| brain | 34% | 109.79 | 910 / 2642 | 1% | 0.09 | 8 / 705 |
| adipose | 30% | 34.67 | 361 / 1204 | 0% | 0 | 0 / 0 |
| thymus | 11% | 17.66 | 73 / 653 | 12% | 9.09 | 72 / 605 |
| pancreas | 1% | 0.89 | 4 / 328 | 12% | 1.23 | 22 / 178 |
| kidney | 6% | 7.37 | 5 / 89 | 0% | 0.04 | 3 / 901 |
| liver | 4% | 2.96 | 9 / 226 | 0% | 0.01 | 1 / 406 |
| muscle | 3% | 3.29 | 23 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 2% | 2.78 | 25 / 1335 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.54 | 2 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071300 | Biological process | cellular response to retinoic acid |
| GO_0071636 | Biological process | positive regulation of transforming growth factor beta production |
| GO_0002931 | Biological process | response to ischemia |
| GO_0000278 | Biological process | mitotic cell cycle |
| GO_0014856 | Biological process | skeletal muscle cell proliferation |
| GO_0060252 | Biological process | positive regulation of glial cell proliferation |
| GO_1901533 | Biological process | negative regulation of hematopoietic progenitor cell differentiation |
| GO_0048661 | Biological process | positive regulation of smooth muscle cell proliferation |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0043525 | Biological process | positive regulation of neuron apoptotic process |
| GO_0045064 | Biological process | T-helper 2 cell differentiation |
| GO_0030218 | Biological process | erythrocyte differentiation |
| GO_0032967 | Biological process | positive regulation of collagen biosynthetic process |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0001666 | Biological process | response to hypoxia |
| GO_1902895 | Biological process | positive regulation of miRNA transcription |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0045653 | Biological process | negative regulation of megakaryocyte differentiation |
| GO_2000845 | Biological process | positive regulation of testosterone secretion |
| GO_1904899 | Biological process | positive regulation of hepatic stellate cell proliferation |
| GO_2000491 | Biological process | positive regulation of hepatic stellate cell activation |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0070301 | Biological process | cellular response to hydrogen peroxide |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0061515 | Biological process | myeloid cell development |
| GO_0005634 | Cellular component | nucleus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0016363 | Cellular component | nuclear matrix |
| GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MYB |
| Protein name | MYB proto-oncogene, transcription factor Transcriptional activator Myb (Proto-oncogene c-Myb) V-myb myeloblastosis viral oncogene homologue (Avian) (V-myb myeloblastosis viral oncogene homolog (Avian), isoform CRA_k) V-myb myeloblastosis viral oncogene homologue (Avian) (MYB proto-oncogene, transcription factor) (V-myb myeloblastosis viral oncogene homolog (Avian), isoform CRA_e) V-myb myeloblastosis viral oncogene homologue (Avian) (V-myb myeloblastosis viral oncogene homolog (Avian), isoform CRA_d) V-myb myeloblastosis viral oncogene homologue (Avian) (V-myb myeloblastosis viral oncogene homolog (Avian), isoform CRA_l) V-myb myeloblastosis viral oncogene homologue (Avian) (MYB proto-oncogene, transcription factor) (V-myb myeloblastosis viral oncogene homolog (Avian), isoform CRA_i) C-myb v-myb myeloblastosis viral oncogene homologue (avian), exon 1 and joined CDS (V-myb myeloblastosis viral oncogene homolog (Avian)) |
| Synonyms | c-myb hCG_32380 |
| Description | FUNCTION: Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. |
| Accessions | ENST00000529262.5 ENST00000525369.5 [P10242-11] Q708E6 P10242 E9PLN0 Q708E8 A0A0C4DG19 ENST00000526889.5 H0YCN6 ENST00000316528.12 ENST00000420123.6 E9PN43 ENST00000528140.5 ENST00000528345.5 E9PPR4 ENST00000616088.4 ENST00000534121.5 [P10242-8] ENST00000526187.5 E9PIW4 E9PJT2 E9PPL8 ENST00000526565.5 ENST00000534736.1 ENST00000525514.5 [P10242-3] ENST00000367814.8 [P10242-1] E9PKZ3 E9PNH6 ENST00000463282.6 ENST00000531737.5 ENST00000367812.6 [P10242-6] ENST00000341911.10 [P10242-4] Q708E5 Q708E3 ENST00000526320.5 E9PN92 ENST00000531634.5 ENST00000533384.5 [P10242-5] ENST00000525477.5 [P10242-3] E9PJ96 Q708E9 ENST00000533624.5 [P10242-9] ENST00000525002.5 ENST00000438901.6 Q708E1 F8W8G5 ENST00000528774.5 [P10242-7] ENST00000528343.5 E9PP87 ENST00000533837.5 [P10242-5] ENST00000529586.5 [P10242-3] E9PMQ0 ENST00000528015.5 ENST00000524588.5 ENST00000442647.7 [P10242-2] ENST00000531519.5 ENST00000533808.5 [P10242-5] ENST00000525940.5 E9PJF1 E9PMZ0 E9PQQ2 ENST00000527615.5 ENST00000339290.9 ENST00000430686.2 ENST00000534044.5 [P10242-10] A0A087WTI6 |
