EID1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030154Biological processcell differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0005654Cellular componentnucleoplasm
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0035035Molecular functionhistone acetyltransferase binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameEID1
Protein nameEP300 interacting inhibitor of differentiation 1
EP300-interacting inhibitor of differentiation 1 (21 kDa pRb-associated protein) (CREBBP/EP300 inhibitory protein 1) (E1A-like inhibitor of differentiation 1) (EID-1)
SynonymsC15orf3
PTD014
RBP21
PNAS-22
CRI1
DescriptionFUNCTION: Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms. .

AccessionsH0YN68
ENST00000530028.3 [Q9Y6B2-1]
ENST00000560490.1
Q9Y6B2