SBNO2 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	7 studies	22% ± 6%	Explore
endothelial cell of lymphatic vessel	3 studies	19% ± 4%	Explore
myeloid cell	3 studies	17% ± 2%	Explore
epithelial cell	3 studies	34% ± 5%	Explore
vein endothelial cell	3 studies	25% ± 6%	Explore
macrophage	3 studies	20% ± 4%	Explore

Name	Number of supported studies	Average coverage
lung	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7869.43	1443 / 1445	100%	78.22	183 / 183
intestine	100%	6756.46	966 / 966	100%	56.07	525 / 527
uterus	100%	6889.83	170 / 170	100%	69.43	457 / 459
skin	100%	8384.29	1809 / 1809	99%	60.88	469 / 472
bladder	100%	7283.14	21 / 21	99%	55.46	498 / 504
lung	100%	15226.73	577 / 578	99%	59.78	1143 / 1155
thymus	100%	8582.69	652 / 653	99%	33.09	598 / 605
breast	100%	9563.04	458 / 459	99%	51.10	1103 / 1118
stomach	99%	5616.87	356 / 359	99%	57.29	283 / 286
prostate	100%	10172.27	244 / 245	98%	39.46	494 / 502
ovary	100%	6583.09	180 / 180	98%	47.31	421 / 430
kidney	100%	9705.88	89 / 89	97%	33.23	878 / 901
adrenal gland	100%	8582.70	258 / 258	91%	26.03	210 / 230
pancreas	88%	2802.54	287 / 328	99%	66.87	176 / 178
liver	95%	4706.27	214 / 226	85%	20.54	346 / 406
brain	29%	802.00	772 / 2642	85%	18.48	597 / 705
eye	0%	0	0 / 0	100%	49.91	80 / 80
lymph node	0%	0	0 / 0	100%	64.39	29 / 29
spleen	100%	13589.27	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	87.60	45 / 45
ureter	0%	0	0 / 0	100%	29.24	1 / 1
adipose	100%	10627.61	1203 / 1204	0%	0	0 / 0
peripheral blood	100%	20372.54	925 / 929	0%	0	0 / 0
blood vessel	99%	7254.21	1324 / 1335	0%	0	0 / 0
muscle	83%	4799.73	668 / 803	0%	0	0 / 0
heart	76%	3411.76	653 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0071222	Biological process	cellular response to lipopolysaccharide
GO_0002281	Biological process	macrophage activation involved in immune response
GO_0061430	Biological process	bone trabecula morphogenesis
GO_1990830	Biological process	cellular response to leukemia inhibitory factor
GO_0050727	Biological process	regulation of inflammatory response
GO_0071348	Biological process	cellular response to interleukin-11
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0030282	Biological process	bone mineralization
GO_0030316	Biological process	osteoclast differentiation
GO_0071354	Biological process	cellular response to interleukin-6
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0072675	Biological process	osteoclast fusion
GO_0005575	Cellular component	cellular_component
GO_0005634	Cellular component	nucleus
GO_0031490	Molecular function	chromatin DNA binding
GO_0042393	Molecular function	histone binding

Gene name	SBNO2
Protein name	SBNO2 protein Protein strawberry notch homolog 2 Strawberry notch homolog 2
Synonyms	KIAA0963
Description	FUNCTION: Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages . Plays a role as a regulator in the pro-inflammatory cascade . .
Accessions	ENST00000590998.5 ENST00000631778.1 K7ERL2 Q9Y2G9 ENST00000632777.1 ENST00000587655.2 ENST00000587024.5 ENST00000634172.1 K7ENA9 K7ES28 ENST00000590176.5 ENST00000622719.2 [Q9Y2G9-3] ENST00000633604.1 ENST00000612198.3 [Q9Y2G9-1] ENST00000438103.6 [Q9Y2G9-3] ENST00000631948.1 [Q9Y2G9-1] A0JNW0 ENST00000361757.8 [Q9Y2G9-1]

SBNO2 report