Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 21% ± 4% | |
| fibroblast | 6 studies | 19% ± 4% | |
| natural killer cell | 5 studies | 18% ± 3% | |
| B cell | 5 studies | 22% ± 5% | |
| CD8-positive, alpha-beta T cell | 5 studies | 20% ± 4% | |
| CD8-positive, alpha-beta memory T cell | 5 studies | 19% ± 5% | |
| CD16-positive, CD56-dim natural killer cell, human | 4 studies | 18% ± 1% | |
| classical monocyte | 4 studies | 22% ± 6% | |
| epithelial cell | 4 studies | 35% ± 10% | |
| ciliated cell | 4 studies | 26% ± 7% | |
| CD4-positive, alpha-beta T cell | 3 studies | 22% ± 4% | |
| effector memory CD8-positive, alpha-beta T cell | 3 studies | 22% ± 5% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 20% ± 3% | |
| non-classical monocyte | 3 studies | 22% ± 4% | |
| GABAergic neuron | 3 studies | 18% ± 2% | |
| glutamatergic neuron | 3 studies | 23% ± 6% | |
| dendritic cell | 3 studies | 28% ± 7% | |
| gamma-delta T cell | 3 studies | 25% ± 14% | |
| naive B cell | 3 studies | 18% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 1004.20 | 2642 / 2642 | 100% | 9.91 | 705 / 705 |
| thymus | 100% | 932.57 | 653 / 653 | 100% | 8.67 | 604 / 605 |
| uterus | 100% | 1166.19 | 170 / 170 | 100% | 8.37 | 458 / 459 |
| lung | 100% | 888.26 | 578 / 578 | 100% | 6.90 | 1152 / 1155 |
| prostate | 100% | 942.37 | 245 / 245 | 100% | 8.00 | 500 / 502 |
| breast | 100% | 1055.71 | 459 / 459 | 100% | 9.58 | 1113 / 1118 |
| liver | 100% | 539.47 | 226 / 226 | 100% | 6.12 | 404 / 406 |
| adrenal gland | 100% | 1068.99 | 258 / 258 | 99% | 10.61 | 228 / 230 |
| pancreas | 99% | 482.33 | 326 / 328 | 99% | 6.63 | 177 / 178 |
| bladder | 100% | 1022.95 | 21 / 21 | 99% | 7.25 | 497 / 504 |
| esophagus | 100% | 831.40 | 1445 / 1445 | 98% | 5.00 | 180 / 183 |
| kidney | 100% | 794.22 | 89 / 89 | 98% | 6.04 | 885 / 901 |
| ovary | 100% | 1345.05 | 180 / 180 | 98% | 4.92 | 422 / 430 |
| stomach | 100% | 645.75 | 359 / 359 | 98% | 6.29 | 279 / 286 |
| intestine | 100% | 943.50 | 966 / 966 | 97% | 7.12 | 513 / 527 |
| skin | 100% | 943.72 | 1808 / 1809 | 96% | 8.15 | 453 / 472 |
| adipose | 100% | 1010.24 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 922.77 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 10.65 | 29 / 29 |
| spleen | 100% | 1035.95 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 7.06 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.53 | 1 / 1 |
| muscle | 100% | 855.32 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 599.41 | 853 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 792.20 | 903 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 75% | 3.89 | 60 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0033077 | Biological process | T cell differentiation in thymus |
| GO_0030851 | Biological process | granulocyte differentiation |
| GO_0046638 | Biological process | positive regulation of alpha-beta T cell differentiation |
| GO_0007219 | Biological process | Notch signaling pathway |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0035019 | Biological process | somatic stem cell population maintenance |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0071425 | Biological process | hematopoietic stem cell proliferation |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0031490 | Molecular function | chromatin DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003729 | Molecular function | mRNA binding |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0060090 | Molecular function | molecular adaptor activity |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | NKAP |
| Protein name | NKAP protein NFKB activating protein NF-kappa-B-activating protein |
| Synonyms | |
| Description | FUNCTION: Acts as a transcriptional repressor . Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development . Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter. . |
| Accessions | A0PJ73 Q05D22 ENST00000371410.5 A0A494C050 Q8N5F7 ENST00000652253.1 |