Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 8 studies | 32% ± 15% | |
| endothelial cell | 6 studies | 23% ± 4% | |
| astrocyte | 5 studies | 23% ± 5% | |
| mast cell | 4 studies | 20% ± 3% | |
| pericyte | 4 studies | 21% ± 5% | |
| epithelial cell | 3 studies | 26% ± 6% | |
| smooth muscle cell | 3 studies | 18% ± 2% |
Insufficient scRNA-seq data for expression of SOX13 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 7179.81 | 245 / 245 | 100% | 23.16 | 500 / 502 |
| ovary | 99% | 3619.61 | 179 / 180 | 100% | 34.94 | 428 / 430 |
| breast | 100% | 5957.47 | 459 / 459 | 99% | 35.59 | 1105 / 1118 |
| intestine | 100% | 4813.21 | 965 / 966 | 98% | 19.51 | 517 / 527 |
| esophagus | 100% | 2857.47 | 1443 / 1445 | 98% | 24.14 | 179 / 183 |
| liver | 98% | 2100.52 | 222 / 226 | 97% | 20.03 | 395 / 406 |
| bladder | 100% | 5691.86 | 21 / 21 | 95% | 20.56 | 480 / 504 |
| pancreas | 97% | 1798.85 | 319 / 328 | 98% | 20.28 | 174 / 178 |
| skin | 96% | 2636.75 | 1738 / 1809 | 99% | 60.63 | 465 / 472 |
| stomach | 99% | 2202.96 | 354 / 359 | 94% | 17.36 | 270 / 286 |
| uterus | 100% | 9377.35 | 170 / 170 | 92% | 19.75 | 424 / 459 |
| lung | 100% | 7147.57 | 578 / 578 | 92% | 19.46 | 1064 / 1155 |
| brain | 88% | 1454.81 | 2330 / 2642 | 99% | 34.68 | 701 / 705 |
| thymus | 100% | 3620.30 | 652 / 653 | 86% | 11.00 | 521 / 605 |
| kidney | 100% | 4656.57 | 89 / 89 | 81% | 16.47 | 730 / 901 |
| adrenal gland | 99% | 2770.34 | 255 / 258 | 56% | 6.05 | 128 / 230 |
| adipose | 100% | 6552.87 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.22 | 1 / 1 |
| blood vessel | 100% | 5599.12 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2640.51 | 240 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 21.06 | 43 / 45 |
| heart | 95% | 1702.76 | 814 / 861 | 0% | 0 | 0 / 0 |
| muscle | 95% | 2283.79 | 759 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 84% | 9.83 | 67 / 80 |
| peripheral blood | 3% | 33.15 | 26 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0021529 | Biological process | spinal cord oligodendrocyte cell differentiation |
| GO_0045588 | Biological process | positive regulation of gamma-delta T cell differentiation |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_0042492 | Biological process | gamma-delta T cell differentiation |
| GO_0045165 | Biological process | cell fate commitment |
| GO_0090336 | Biological process | positive regulation of brown fat cell differentiation |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0009653 | Biological process | anatomical structure morphogenesis |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| GO_0000976 | Molecular function | transcription cis-regulatory region binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0001217 | Molecular function | DNA-binding transcription repressor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SOX13 |
| Protein name | SRY-box transcription factor 13 Transcription factor SOX-13 (Islet cell antigen 12) (SRY (Sex determining region Y)-box 13) (Type 1 diabetes autoantigen ICA12) |
| Synonyms | |
| Description | FUNCTION: Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3' . Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube (By similarity). Binds to the gene promoter of MBP and acts as a transcriptional repressor (By similarity). Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells (By similarity). Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells (By similarity). Promotes brown adipocyte differentiation (By similarity). Inhibitor of WNT signaling . . |
| Accessions | E9PPW0 ENST00000525442.1 Q9UN79 H0YDQ5 ENST00000480326.1 ENST00000528591.5 E9PKD6 ENST00000367204.6 ENST00000618875.4 |
