PITX1 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of PITX1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
stomach	99%	3991.88	357 / 359	93%	52.22	265 / 286
esophagus	89%	25894.35	1289 / 1445	98%	182.76	179 / 183
bladder	100%	9279.86	21 / 21	81%	52.17	409 / 504
intestine	65%	797.83	626 / 966	95%	57.60	501 / 527
prostate	95%	2274.54	232 / 245	30%	5.38	152 / 502
tonsil	0%	0	0 / 0	100%	305.12	45 / 45
ureter	0%	0	0 / 0	100%	17.88	1 / 1
uterus	5%	324.76	8 / 170	91%	173.30	418 / 459
breast	3%	22.31	13 / 459	76%	35.55	847 / 1118
muscle	79%	796.29	631 / 803	0%	0	0 / 0
lung	4%	23.96	24 / 578	71%	52.72	819 / 1155
pancreas	0%	10.30	1 / 328	72%	28.79	128 / 178
ovary	2%	5.53	3 / 180	53%	24.34	229 / 430
blood vessel	53%	806.48	701 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	31%	11.47	9 / 29
adrenal gland	12%	97.22	31 / 258	16%	5.47	36 / 230
liver	0%	0	0 / 226	22%	4.79	88 / 406
skin	15%	94.25	276 / 1809	5%	1.29	22 / 472
brain	0%	1.19	4 / 2642	9%	2.20	63 / 705
adipose	9%	48.81	108 / 1204	0%	0	0 / 0
kidney	0%	0	0 / 89	5%	1.03	42 / 901
peripheral blood	4%	33.40	41 / 929	0%	0	0 / 0
thymus	1%	5.04	5 / 653	2%	0.84	12 / 605
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0

GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0048625	Biological process	myoblast fate commitment
GO_0035116	Biological process	embryonic hindlimb morphogenesis
GO_0014707	Biological process	branchiomeric skeletal muscle development
GO_0009653	Biological process	anatomical structure morphogenesis
GO_0001501	Biological process	skeletal system development
GO_0021983	Biological process	pituitary gland development
GO_0051216	Biological process	cartilage development
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005737	Cellular component	cytoplasm
GO_0000785	Cellular component	chromatin
GO_0005667	Cellular component	transcription regulator complex
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0061629	Molecular function	RNA polymerase II-specific DNA-binding transcription factor binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0005515	Molecular function	protein binding

Gene name	PITX1
Protein name	Paired like homeodomain 1 Pituitary homeobox 1 (Homeobox protein PITX1) (Paired-like homeodomain transcription factor 1) Pituitary homeobox 1 (Hindlimb-expressed homeobox protein backfoot) (Homeobox protein PITX1) (Paired-like homeodomain transcription factor 1)
Synonyms	PTX1 BFT
Description	FUNCTION: Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. .
Accessions	D6R9U1 P78337 ENST00000265340.12 ENST00000502676.1 X5D9A5 ENST00000506438.5 ENST00000507253.5 D6R955

PITX1 report