ZMYND11 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006325Biological processchromatin organization
GO_0051607Biological processdefense response to virus
GO_0009966Biological processregulation of signal transduction
GO_0034243Biological processregulation of transcription elongation by RNA polymerase II
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0043124Biological processnegative regulation of canonical NF-kappaB signal transduction
GO_0046329Biological processnegative regulation of JNK cascade
GO_2001237Biological processnegative regulation of extrinsic apoptotic signaling pathway
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0003690Molecular functiondouble-stranded DNA binding
GO_0035064Molecular functionmethylated histone binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameZMYND11
Protein nameZinc finger MYND-type containing 11
ZMYND11 protein
Zinc finger MYND domain containing 11 transcript variant 3
Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A-binding protein) (Bone morphogenetic protein receptor-associated molecule 1) (Protein BS69)
Zinc finger MYND domain-containing protein 11
SynonymsBS69
BRAM1
DescriptionFUNCTION: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA . Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth. .; FUNCTION: (Microbial infection) Inhibits Epstein-Barr virus EBNA2-mediated transcriptional activation and host cell proliferation, through direct interaction. .

AccessionsENST00000602682.6 [Q15326-5]
ENST00000381604
A0A994J6Y5
E9PE09
A0A994J4J2
E7EV75
J3QKD2
ENST00000704343.1
Q15326
ENST00000509513.6 [Q15326-6]
ENST00000558098.4 [Q15326-3]
A0A994J7D2
ENST00000704301.1 [Q15326-1]
ENST00000704306.1
E7ENI9
ENST00000704307.1
ENST00000704295.1 [Q15326-2]
A0A994J4C0
A0A994J4I8
ENST00000397955.7
ENST00000704303.1 [Q15326-2]
ENST00000704315.1
ENST00000439456.5
ENST00000704338.1
ENST00000397962.8 [Q15326-1]
A0A0D9SGD6
A0A0A0MRY2
ENST00000381591.5 [Q15326-1]
ENST00000381604.9 [Q15326-1]
ENST00000381584.6
Q5UGI2
ENST00000402736.5
Q6PJR5
Q5BJG6
ENST00000704339.1
A0A994J4Y4
ENST00000627286.2
ENST00000704335.1 [Q15326-4]
B0QZE2
ENST00000403354.5