Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 24 studies | 29% ± 12% | |
fibroblast | 14 studies | 23% ± 7% | |
astrocyte | 13 studies | 33% ± 15% | |
oligodendrocyte | 11 studies | 32% ± 11% | |
GABAergic neuron | 10 studies | 37% ± 23% | |
glutamatergic neuron | 10 studies | 42% ± 23% | |
microglial cell | 10 studies | 32% ± 10% | |
oligodendrocyte precursor cell | 10 studies | 35% ± 15% | |
smooth muscle cell | 9 studies | 21% ± 3% | |
type I pneumocyte | 8 studies | 23% ± 9% | |
pericyte | 7 studies | 24% ± 7% | |
endothelial cell of lymphatic vessel | 6 studies | 28% ± 8% | |
neuron | 6 studies | 35% ± 14% | |
interneuron | 6 studies | 50% ± 25% | |
macrophage | 6 studies | 32% ± 8% | |
epithelial cell | 6 studies | 36% ± 16% | |
retina horizontal cell | 6 studies | 22% ± 7% | |
adipocyte | 6 studies | 26% ± 5% | |
amacrine cell | 5 studies | 22% ± 7% | |
Mueller cell | 5 studies | 22% ± 8% | |
basal cell | 5 studies | 28% ± 13% | |
connective tissue cell | 5 studies | 18% ± 2% | |
club cell | 5 studies | 22% ± 10% | |
natural killer cell | 4 studies | 19% ± 4% | |
granule cell | 4 studies | 29% ± 6% | |
myofibroblast cell | 4 studies | 24% ± 8% | |
retinal bipolar neuron | 4 studies | 18% ± 3% | |
cardiac muscle cell | 4 studies | 19% ± 1% | |
ciliated cell | 4 studies | 24% ± 6% | |
lymphocyte | 4 studies | 25% ± 7% | |
type II pneumocyte | 4 studies | 22% ± 6% | |
GABAergic interneuron | 3 studies | 37% ± 2% | |
glial cell | 3 studies | 24% ± 3% | |
retinal ganglion cell | 3 studies | 24% ± 1% | |
retinal cone cell | 3 studies | 22% ± 6% | |
vein endothelial cell | 3 studies | 24% ± 11% | |
GABAergic amacrine cell | 3 studies | 23% ± 7% | |
glycinergic amacrine cell | 3 studies | 23% ± 5% | |
retinal rod cell | 3 studies | 22% ± 1% | |
rod bipolar cell | 3 studies | 20% ± 6% | |
endothelial cell of vascular tree | 3 studies | 25% ± 13% | |
myeloid cell | 3 studies | 17% ± 1% | |
T cell | 3 studies | 21% ± 2% | |
goblet cell | 3 studies | 29% ± 15% | |
transit amplifying cell | 3 studies | 30% ± 18% | |
mast cell | 3 studies | 20% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 7339.33 | 1444 / 1445 | 100% | 50.86 | 183 / 183 |
prostate | 100% | 6520.84 | 245 / 245 | 100% | 74.02 | 501 / 502 |
breast | 100% | 6653.22 | 459 / 459 | 100% | 96.13 | 1115 / 1118 |
brain | 100% | 8559.35 | 2642 / 2642 | 100% | 101.32 | 703 / 705 |
lung | 100% | 5642.44 | 576 / 578 | 100% | 48.42 | 1151 / 1155 |
thymus | 100% | 9712.06 | 653 / 653 | 99% | 92.05 | 598 / 605 |
ovary | 100% | 7095.02 | 180 / 180 | 99% | 43.42 | 425 / 430 |
bladder | 100% | 8848.48 | 21 / 21 | 98% | 46.00 | 495 / 504 |
pancreas | 99% | 3422.02 | 325 / 328 | 99% | 50.23 | 176 / 178 |
intestine | 100% | 7721.90 | 966 / 966 | 98% | 39.66 | 516 / 527 |
stomach | 100% | 5193.48 | 359 / 359 | 98% | 43.00 | 279 / 286 |
uterus | 100% | 8378.79 | 170 / 170 | 97% | 43.86 | 447 / 459 |
kidney | 100% | 4799.82 | 89 / 89 | 97% | 51.09 | 875 / 901 |
adrenal gland | 100% | 4824.43 | 258 / 258 | 95% | 49.89 | 218 / 230 |
skin | 100% | 5008.55 | 1806 / 1809 | 91% | 38.01 | 430 / 472 |
liver | 97% | 1965.14 | 219 / 226 | 86% | 26.41 | 351 / 406 |
adipose | 100% | 6414.21 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 9072.43 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 3898.24 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 17.74 | 1 / 1 |
muscle | 100% | 5924.35 | 802 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 30.02 | 43 / 45 |
heart | 95% | 4248.79 | 819 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 85% | 33.25 | 68 / 80 |
lymph node | 0% | 0 | 0 / 0 | 59% | 13.19 | 17 / 29 |
peripheral blood | 26% | 571.81 | 240 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006325 | Biological process | chromatin organization |
GO_0051607 | Biological process | defense response to virus |
GO_0009966 | Biological process | regulation of signal transduction |
GO_0034243 | Biological process | regulation of transcription elongation by RNA polymerase II |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0043124 | Biological process | negative regulation of canonical NF-kappaB signal transduction |
GO_0046329 | Biological process | negative regulation of JNK cascade |
GO_2001237 | Biological process | negative regulation of extrinsic apoptotic signaling pathway |
GO_0005694 | Cellular component | chromosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0003690 | Molecular function | double-stranded DNA binding |
GO_0035064 | Molecular function | methylated histone binding |
GO_0003714 | Molecular function | transcription corepressor activity |
GO_0005515 | Molecular function | protein binding |
GO_0008270 | Molecular function | zinc ion binding |
Gene name | ZMYND11 |
Protein name | Zinc finger MYND-type containing 11 ZMYND11 protein Zinc finger MYND domain containing 11 transcript variant 3 Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A-binding protein) (Bone morphogenetic protein receptor-associated molecule 1) (Protein BS69) Zinc finger MYND domain-containing protein 11 |
Synonyms | BS69 BRAM1 |
Description | FUNCTION: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA . Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth. .; FUNCTION: (Microbial infection) Inhibits Epstein-Barr virus EBNA2-mediated transcriptional activation and host cell proliferation, through direct interaction. . |
Accessions | ENST00000602682.6 [Q15326-5] ENST00000381604 A0A994J6Y5 E9PE09 A0A994J4J2 E7EV75 J3QKD2 ENST00000704343.1 Q15326 ENST00000509513.6 [Q15326-6] ENST00000558098.4 [Q15326-3] A0A994J7D2 ENST00000704301.1 [Q15326-1] ENST00000704306.1 E7ENI9 ENST00000704307.1 ENST00000704295.1 [Q15326-2] A0A994J4C0 A0A994J4I8 ENST00000397955.7 ENST00000704303.1 [Q15326-2] ENST00000704315.1 ENST00000439456.5 ENST00000704338.1 ENST00000397962.8 [Q15326-1] A0A0D9SGD6 A0A0A0MRY2 ENST00000381591.5 [Q15326-1] ENST00000381604.9 [Q15326-1] ENST00000381584.6 Q5UGI2 ENST00000402736.5 Q6PJR5 Q5BJG6 ENST00000704339.1 A0A994J4Y4 ENST00000627286.2 ENST00000704335.1 [Q15326-4] B0QZE2 ENST00000403354.5 |