Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 25 studies | 45% ± 18% | |
| macrophage | 20 studies | 44% ± 25% | |
| astrocyte | 19 studies | 54% ± 17% | |
| fibroblast | 17 studies | 37% ± 17% | |
| microglial cell | 16 studies | 56% ± 16% | |
| oligodendrocyte | 15 studies | 65% ± 14% | |
| oligodendrocyte precursor cell | 14 studies | 59% ± 17% | |
| mast cell | 14 studies | 44% ± 15% | |
| glutamatergic neuron | 13 studies | 69% ± 23% | |
| pericyte | 12 studies | 42% ± 16% | |
| ciliated cell | 11 studies | 37% ± 21% | |
| GABAergic neuron | 11 studies | 69% ± 23% | |
| smooth muscle cell | 11 studies | 46% ± 14% | |
| T cell | 10 studies | 41% ± 21% | |
| type I pneumocyte | 9 studies | 46% ± 27% | |
| CD8-positive, alpha-beta T cell | 9 studies | 36% ± 19% | |
| myeloid cell | 9 studies | 43% ± 17% | |
| regulatory T cell | 9 studies | 30% ± 17% | |
| epithelial cell | 8 studies | 48% ± 21% | |
| adipocyte | 8 studies | 37% ± 12% | |
| natural killer cell | 7 studies | 35% ± 15% | |
| leukocyte | 7 studies | 49% ± 26% | |
| basal cell | 7 studies | 42% ± 24% | |
| retinal cone cell | 7 studies | 57% ± 31% | |
| dendritic cell | 7 studies | 40% ± 13% | |
| CD8-positive, alpha-beta memory T cell | 7 studies | 23% ± 8% | |
| classical monocyte | 6 studies | 26% ± 7% | |
| neuron | 6 studies | 58% ± 16% | |
| interneuron | 6 studies | 65% ± 30% | |
| retinal ganglion cell | 6 studies | 53% ± 27% | |
| effector memory CD8-positive, alpha-beta T cell | 6 studies | 39% ± 18% | |
| mesothelial cell | 6 studies | 46% ± 15% | |
| retinal rod cell | 6 studies | 61% ± 32% | |
| endothelial cell of lymphatic vessel | 6 studies | 30% ± 12% | |
| monocyte | 6 studies | 53% ± 19% | |
| club cell | 6 studies | 39% ± 19% | |
| CD4-positive, alpha-beta T cell | 5 studies | 51% ± 20% | |
| plasma cell | 5 studies | 54% ± 23% | |
| cardiac muscle cell | 5 studies | 59% ± 14% | |
| type II pneumocyte | 5 studies | 60% ± 10% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 4 studies | 35% ± 17% | |
| non-classical monocyte | 4 studies | 21% ± 7% | |
| cholangiocyte | 4 studies | 56% ± 20% | |
| hepatocyte | 4 studies | 63% ± 31% | |
| granule cell | 4 studies | 53% ± 19% | |
| B cell | 4 studies | 26% ± 7% | |
| lymphocyte | 4 studies | 54% ± 21% | |
| Mueller cell | 4 studies | 52% ± 15% | |
| OFF-bipolar cell | 4 studies | 40% ± 22% | |
| amacrine cell | 4 studies | 69% ± 9% | |
| retina horizontal cell | 4 studies | 46% ± 22% | |
| mature NK T cell | 4 studies | 32% ± 18% | |
| myofibroblast cell | 4 studies | 42% ± 19% | |
| exhausted T cell | 3 studies | 30% ± 16% | |
| differentiation-committed oligodendrocyte precursor | 3 studies | 61% ± 8% | |
| GABAergic interneuron | 3 studies | 69% ± 17% | |
| glial cell | 3 studies | 43% ± 18% | |
| progenitor cell | 3 studies | 28% ± 7% | |
| mononuclear phagocyte | 3 studies | 35% ± 13% | |
| mucosal invariant T cell | 3 studies | 42% ± 22% | |
| GABAergic amacrine cell | 3 studies | 53% ± 18% | |
| ON-bipolar cell | 3 studies | 50% ± 20% | |
| glycinergic amacrine cell | 3 studies | 57% ± 14% | |
| rod bipolar cell | 3 studies | 53% ± 27% | |
| endothelial cell of vascular tree | 3 studies | 31% ± 13% | |
| retinal pigment epithelial cell | 3 studies | 57% ± 23% | |
| abnormal cell | 3 studies | 31% ± 16% | |
| ependymal cell | 3 studies | 80% ± 9% | |
| alveolar macrophage | 3 studies | 72% ± 12% | |
| respiratory goblet cell | 3 studies | 47% ± 19% | |
| T follicular helper cell | 3 studies | 17% ± 0% | |
| muscle cell | 3 studies | 45% ± 26% | |
| goblet cell | 3 studies | 32% ± 10% | |
| mural cell | 3 studies | 57% ± 1% | |
| mucus secreting cell | 3 studies | 49% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 4157.46 | 2639 / 2642 | 100% | 12.71 | 704 / 705 |
| esophagus | 100% | 3049.62 | 1445 / 1445 | 99% | 9.55 | 181 / 183 |
| lung | 100% | 4285.91 | 578 / 578 | 99% | 9.46 | 1140 / 1155 |
| breast | 100% | 2583.90 | 459 / 459 | 98% | 11.67 | 1094 / 1118 |
| skin | 100% | 2553.45 | 1806 / 1809 | 96% | 8.60 | 454 / 472 |
| thymus | 100% | 3935.68 | 653 / 653 | 96% | 8.23 | 580 / 605 |
| prostate | 100% | 4605.58 | 245 / 245 | 96% | 8.66 | 480 / 502 |
| pancreas | 99% | 1427.36 | 324 / 328 | 97% | 8.52 | 172 / 178 |
| intestine | 100% | 3981.18 | 966 / 966 | 95% | 5.90 | 500 / 527 |
| stomach | 100% | 2596.02 | 359 / 359 | 95% | 7.24 | 271 / 286 |
| ovary | 100% | 3100.52 | 180 / 180 | 94% | 6.32 | 405 / 430 |
| kidney | 100% | 2194.06 | 89 / 89 | 93% | 7.90 | 840 / 901 |
| uterus | 100% | 5688.53 | 170 / 170 | 91% | 6.23 | 419 / 459 |
| adrenal gland | 99% | 1970.08 | 256 / 258 | 82% | 5.38 | 189 / 230 |
| bladder | 100% | 3940.05 | 21 / 21 | 80% | 5.30 | 403 / 504 |
| liver | 99% | 1526.91 | 224 / 226 | 78% | 3.83 | 317 / 406 |
| adipose | 100% | 2494.26 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 4628.35 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 4013.79 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3357.63 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 3748.85 | 915 / 929 | 0% | 0 | 0 / 0 |
| heart | 96% | 2090.38 | 823 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 7.02 | 41 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 79% | 4.82 | 23 / 29 |
| eye | 0% | 0 | 0 / 0 | 48% | 1.75 | 38 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007612 | Biological process | learning |
| GO_0006396 | Biological process | RNA processing |
| GO_0051168 | Biological process | nuclear export |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0007420 | Biological process | brain development |
| GO_0007613 | Biological process | memory |
| GO_0035176 | Biological process | social behavior |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0007399 | Biological process | nervous system development |
| GO_0042405 | Cellular component | nuclear inclusion body |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0016363 | Cellular component | nuclear matrix |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0034046 | Molecular function | poly(G) binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0008266 | Molecular function | poly(U) RNA binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ATXN1 |
| Protein name | ATXN1 protein Ataxin 1 Ataxin-1 (Spinocerebellar ataxia type 1 protein) |
| Synonyms | SCA1 ATX1 |
| Description | FUNCTION: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism . In concert with CIC and ATXN1L, involved in brain development (By similarity). . |
| Accessions | ENST00000244769.8 [P54253-1] ENST00000436367.6 [P54253-1] Q96FF1 ENST00000642969.1 Q96C81 P54253 A0A2R8YCF3 |