ATXN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007612Biological processlearning
GO_0006396Biological processRNA processing
GO_0051168Biological processnuclear export
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0007420Biological processbrain development
GO_0007613Biological processmemory
GO_0035176Biological processsocial behavior
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0007399Biological processnervous system development
GO_0042405Cellular componentnuclear inclusion body
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0016363Cellular componentnuclear matrix
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0034046Molecular functionpoly(G) binding
GO_0042802Molecular functionidentical protein binding
GO_0008266Molecular functionpoly(U) RNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameATXN1
Protein nameATXN1 protein
Ataxin 1
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
SynonymsSCA1
ATX1
DescriptionFUNCTION: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism . In concert with CIC and ATXN1L, involved in brain development (By similarity). .

AccessionsENST00000244769.8 [P54253-1]
ENST00000436367.6 [P54253-1]
Q96FF1
ENST00000642969.1
Q96C81
P54253
A0A2R8YCF3