Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 25 studies | 45% ± 18% | |
macrophage | 20 studies | 44% ± 25% | |
astrocyte | 19 studies | 54% ± 17% | |
fibroblast | 17 studies | 37% ± 17% | |
microglial cell | 16 studies | 56% ± 16% | |
oligodendrocyte | 15 studies | 65% ± 14% | |
oligodendrocyte precursor cell | 14 studies | 59% ± 17% | |
mast cell | 14 studies | 44% ± 15% | |
glutamatergic neuron | 13 studies | 69% ± 23% | |
pericyte | 12 studies | 42% ± 16% | |
ciliated cell | 11 studies | 37% ± 21% | |
GABAergic neuron | 11 studies | 69% ± 23% | |
smooth muscle cell | 11 studies | 46% ± 14% | |
T cell | 10 studies | 41% ± 21% | |
type I pneumocyte | 9 studies | 46% ± 27% | |
CD8-positive, alpha-beta T cell | 9 studies | 36% ± 19% | |
myeloid cell | 9 studies | 43% ± 17% | |
regulatory T cell | 9 studies | 30% ± 17% | |
epithelial cell | 8 studies | 48% ± 21% | |
adipocyte | 8 studies | 37% ± 12% | |
natural killer cell | 7 studies | 35% ± 15% | |
leukocyte | 7 studies | 49% ± 26% | |
basal cell | 7 studies | 42% ± 24% | |
retinal cone cell | 7 studies | 57% ± 31% | |
dendritic cell | 7 studies | 40% ± 13% | |
CD8-positive, alpha-beta memory T cell | 7 studies | 23% ± 8% | |
classical monocyte | 6 studies | 26% ± 7% | |
neuron | 6 studies | 58% ± 16% | |
interneuron | 6 studies | 65% ± 30% | |
retinal ganglion cell | 6 studies | 53% ± 27% | |
effector memory CD8-positive, alpha-beta T cell | 6 studies | 39% ± 18% | |
mesothelial cell | 6 studies | 46% ± 15% | |
retinal rod cell | 6 studies | 61% ± 32% | |
endothelial cell of lymphatic vessel | 6 studies | 30% ± 12% | |
monocyte | 6 studies | 53% ± 19% | |
club cell | 6 studies | 39% ± 19% | |
CD4-positive, alpha-beta T cell | 5 studies | 51% ± 20% | |
plasma cell | 5 studies | 54% ± 23% | |
cardiac muscle cell | 5 studies | 59% ± 14% | |
type II pneumocyte | 5 studies | 60% ± 10% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 4 studies | 35% ± 17% | |
non-classical monocyte | 4 studies | 21% ± 7% | |
cholangiocyte | 4 studies | 56% ± 20% | |
hepatocyte | 4 studies | 63% ± 31% | |
granule cell | 4 studies | 53% ± 19% | |
B cell | 4 studies | 26% ± 7% | |
lymphocyte | 4 studies | 54% ± 21% | |
Mueller cell | 4 studies | 52% ± 15% | |
OFF-bipolar cell | 4 studies | 40% ± 22% | |
amacrine cell | 4 studies | 69% ± 9% | |
retina horizontal cell | 4 studies | 46% ± 22% | |
mature NK T cell | 4 studies | 32% ± 18% | |
myofibroblast cell | 4 studies | 42% ± 19% | |
exhausted T cell | 3 studies | 30% ± 16% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 61% ± 8% | |
GABAergic interneuron | 3 studies | 69% ± 17% | |
glial cell | 3 studies | 43% ± 18% | |
progenitor cell | 3 studies | 28% ± 7% | |
mononuclear phagocyte | 3 studies | 35% ± 13% | |
mucosal invariant T cell | 3 studies | 42% ± 22% | |
GABAergic amacrine cell | 3 studies | 53% ± 18% | |
ON-bipolar cell | 3 studies | 50% ± 20% | |
glycinergic amacrine cell | 3 studies | 57% ± 14% | |
rod bipolar cell | 3 studies | 53% ± 27% | |
endothelial cell of vascular tree | 3 studies | 31% ± 13% | |
retinal pigment epithelial cell | 3 studies | 57% ± 23% | |
abnormal cell | 3 studies | 31% ± 16% | |
ependymal cell | 3 studies | 80% ± 9% | |
alveolar macrophage | 3 studies | 72% ± 12% | |
respiratory goblet cell | 3 studies | 47% ± 19% | |
T follicular helper cell | 3 studies | 17% ± 0% | |
muscle cell | 3 studies | 45% ± 26% | |
goblet cell | 3 studies | 32% ± 10% | |
mural cell | 3 studies | 57% ± 1% | |
mucus secreting cell | 3 studies | 49% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 4157.46 | 2639 / 2642 | 100% | 12.71 | 704 / 705 |
esophagus | 100% | 3049.62 | 1445 / 1445 | 99% | 9.55 | 181 / 183 |
lung | 100% | 4285.91 | 578 / 578 | 99% | 9.46 | 1140 / 1155 |
breast | 100% | 2583.90 | 459 / 459 | 98% | 11.67 | 1094 / 1118 |
skin | 100% | 2553.45 | 1806 / 1809 | 96% | 8.60 | 454 / 472 |
thymus | 100% | 3935.68 | 653 / 653 | 96% | 8.23 | 580 / 605 |
prostate | 100% | 4605.58 | 245 / 245 | 96% | 8.66 | 480 / 502 |
pancreas | 99% | 1427.36 | 324 / 328 | 97% | 8.52 | 172 / 178 |
intestine | 100% | 3981.18 | 966 / 966 | 95% | 5.90 | 500 / 527 |
stomach | 100% | 2596.02 | 359 / 359 | 95% | 7.24 | 271 / 286 |
ovary | 100% | 3100.52 | 180 / 180 | 94% | 6.32 | 405 / 430 |
kidney | 100% | 2194.06 | 89 / 89 | 93% | 7.90 | 840 / 901 |
uterus | 100% | 5688.53 | 170 / 170 | 91% | 6.23 | 419 / 459 |
adrenal gland | 99% | 1970.08 | 256 / 258 | 82% | 5.38 | 189 / 230 |
bladder | 100% | 3940.05 | 21 / 21 | 80% | 5.30 | 403 / 504 |
liver | 99% | 1526.91 | 224 / 226 | 78% | 3.83 | 317 / 406 |
adipose | 100% | 2494.26 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4628.35 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 4013.79 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3357.63 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 3748.85 | 915 / 929 | 0% | 0 | 0 / 0 |
heart | 96% | 2090.38 | 823 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 7.02 | 41 / 45 |
lymph node | 0% | 0 | 0 / 0 | 79% | 4.82 | 23 / 29 |
eye | 0% | 0 | 0 / 0 | 48% | 1.75 | 38 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007612 | Biological process | learning |
GO_0006396 | Biological process | RNA processing |
GO_0051168 | Biological process | nuclear export |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0007420 | Biological process | brain development |
GO_0007613 | Biological process | memory |
GO_0035176 | Biological process | social behavior |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0007399 | Biological process | nervous system development |
GO_0042405 | Cellular component | nuclear inclusion body |
GO_0005730 | Cellular component | nucleolus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0016363 | Cellular component | nuclear matrix |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0034046 | Molecular function | poly(G) binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0008266 | Molecular function | poly(U) RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ATXN1 |
Protein name | ATXN1 protein Ataxin 1 Ataxin-1 (Spinocerebellar ataxia type 1 protein) |
Synonyms | SCA1 ATX1 |
Description | FUNCTION: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism . In concert with CIC and ATXN1L, involved in brain development (By similarity). . |
Accessions | ENST00000244769.8 [P54253-1] ENST00000436367.6 [P54253-1] Q96FF1 ENST00000642969.1 Q96C81 P54253 A0A2R8YCF3 |