Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 10 studies | 26% ± 7% | |
| glutamatergic neuron | 6 studies | 30% ± 19% | |
| epithelial cell | 5 studies | 28% ± 10% | |
| neuron | 4 studies | 29% ± 8% | |
| interneuron | 4 studies | 31% ± 19% | |
| microglial cell | 3 studies | 19% ± 1% | |
| retinal ganglion cell | 3 studies | 59% ± 17% | |
| abnormal cell | 3 studies | 20% ± 5% | |
| GABAergic neuron | 3 studies | 36% ± 21% | |
| oligodendrocyte | 3 studies | 19% ± 4% | |
| astrocyte | 3 studies | 31% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 4010.71 | 653 / 653 | 100% | 51.55 | 605 / 605 |
| brain | 100% | 8673.02 | 2641 / 2642 | 100% | 87.18 | 705 / 705 |
| esophagus | 100% | 1996.60 | 1442 / 1445 | 100% | 21.75 | 183 / 183 |
| uterus | 100% | 1893.84 | 170 / 170 | 100% | 29.18 | 458 / 459 |
| ovary | 100% | 1734.73 | 180 / 180 | 100% | 33.69 | 429 / 430 |
| kidney | 100% | 2158.45 | 89 / 89 | 100% | 34.79 | 898 / 901 |
| prostate | 100% | 2201.70 | 244 / 245 | 100% | 53.46 | 501 / 502 |
| skin | 100% | 2059.22 | 1804 / 1809 | 99% | 40.78 | 469 / 472 |
| stomach | 100% | 2119.30 | 359 / 359 | 99% | 22.07 | 283 / 286 |
| intestine | 99% | 1539.40 | 961 / 966 | 99% | 22.20 | 524 / 527 |
| breast | 100% | 1896.02 | 458 / 459 | 99% | 32.32 | 1108 / 1118 |
| bladder | 100% | 1540.90 | 21 / 21 | 98% | 23.48 | 495 / 504 |
| adrenal gland | 100% | 2504.01 | 258 / 258 | 97% | 42.02 | 223 / 230 |
| lung | 95% | 1351.52 | 549 / 578 | 98% | 23.28 | 1137 / 1155 |
| pancreas | 91% | 1127.28 | 299 / 328 | 100% | 25.34 | 178 / 178 |
| liver | 44% | 400.08 | 100 / 226 | 91% | 15.15 | 368 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 75.34 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 26.93 | 29 / 29 |
| spleen | 100% | 1623.03 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 28.23 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 27.63 | 1 / 1 |
| adipose | 99% | 1551.45 | 1190 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 1640.54 | 1308 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 92% | 1276.65 | 737 / 803 | 0% | 0 | 0 / 0 |
| heart | 84% | 927.95 | 725 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 60% | 864.50 | 561 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_0033599 | Biological process | regulation of mammary gland epithelial cell proliferation |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0007281 | Biological process | germ cell development |
| GO_0048706 | Biological process | embryonic skeletal system development |
| GO_0001843 | Biological process | neural tube closure |
| GO_0009653 | Biological process | anatomical structure morphogenesis |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | DEAF1 |
| Protein name | DEAF1 transcription factor Deformed epidermal autoregulatory factor 1 homolog Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5) |
| Synonyms | ZMYND5 SPN |
| Description | FUNCTION: Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm. Transcriptional activator of EIF4G3. . |
| Accessions | ENST00000530813.2 ENST00000632113.1 A0A8I5KZ80 O75398 A0A8I5KUA2 A0A0J9YWD6 A0A8I5KR93 ENST00000634194.1 ENST00000382409.4 [O75398-1] ENST00000687329.1 A0A8I5QJC6 H0YCY2 A0A804HIS1 ENST00000686001.1 A0A8I5KQY1 A0A8I5KQJ8 ENST00000689835.1 H0YCH1 ENST00000527170.5 A0A0J9YX80 ENST00000685854.1 ENST00000634067.1 A0A0J9YXA4 ENST00000529717.6 A0A8I5QL28 ENST00000683307.1 ENST00000692634.1 ENST00000690068.1 |
