HMX1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HMX1 at tissue level.

III. Associated gene sets

GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameHMX1
Protein nameH6 family homeobox 1 (Homeobox protein HMX1)
Homeobox protein HMX1 (Homeobox protein H6)
SynonymsH6
DescriptionFUNCTION: DNA-binding protein that binds to the 5'-CAAG-3' core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear. .

AccessionsF1T0J4
Q9NP08
ENST00000506970.2
ENST00000400677.5
ENST00000673238.1