TAF7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000296Biological processspermine transport
GO_0006366Biological processtranscription by RNA polymerase II
GO_0006469Biological processnegative regulation of protein kinase activity
GO_0045347Biological processnegative regulation of MHC class II biosynthetic process
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0051123Biological processRNA polymerase II preinitiation complex assembly
GO_0006282Biological processregulation of DNA repair
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045344Biological processnegative regulation of MHC class I biosynthetic process
GO_0060261Biological processpositive regulation of transcription initiation by RNA polymerase II
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0042789Biological processmRNA transcription by RNA polymerase II
GO_0006367Biological processtranscription initiation at RNA polymerase II promoter
GO_0030520Biological processestrogen receptor signaling pathway
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0006352Biological processDNA-templated transcription initiation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0071339Cellular componentMLL1 complex
GO_0005669Cellular componenttranscription factor TFIID complex
GO_0005654Cellular componentnucleoplasm
GO_0033276Cellular componenttranscription factor TFTC complex
GO_0005737Cellular componentcytoplasm
GO_0001673Cellular componentmale germ cell nucleus
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0001097Molecular functionTFIIH-class transcription factor complex binding
GO_0046966Molecular functionnuclear thyroid hormone receptor binding
GO_0140297Molecular functionDNA-binding transcription factor binding
GO_0000976Molecular functiontranscription cis-regulatory region binding
GO_0106140Molecular functionP-TEFb complex binding
GO_0061628Molecular functionH3K27me3 modified histone binding
GO_0035035Molecular functionhistone acetyltransferase binding
GO_0046982Molecular functionprotein heterodimerization activity
GO_0016251Molecular functionRNA polymerase II general transcription initiation factor activity
GO_0042809Molecular functionnuclear vitamin D receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTAF7
Protein nameTranscription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55)
Transcription initiation factor TFIID subunit 7
SynonymsTAF2F
TAFII55
DescriptionFUNCTION: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription . TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) . The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 . TAF7 forms a promoter DNA binding subcomplex of TFIID, together with TAF1 and TAF2 . Part of a TFIID complex containing TAF10 (TFIID alpha) and a TFIID complex lacking TAF10 (TFIID beta) . .

AccessionsENST00000624761.2
Q15545
A0A096LPC3
ENST00000624761
ENST00000313368.8