MYBBP1A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MYBBP1A at tissue level.

III. Associated gene sets

GO_0042149Biological processcellular response to glucose starvation
GO_0042254Biological processribosome biogenesis
GO_0001649Biological processosteoblast differentiation
GO_0006338Biological processchromatin remodeling
GO_0032922Biological processcircadian regulation of gene expression
GO_0045945Biological processpositive regulation of transcription by RNA polymerase III
GO_0072332Biological processintrinsic apoptotic signaling pathway by p53 class mediator
GO_0045943Biological processpositive regulation of transcription by RNA polymerase I
GO_0022904Biological processrespiratory electron transport chain
GO_0006355Biological processregulation of DNA-templated transcription
GO_1903450Biological processregulation of G1 to G0 transition
GO_2000210Biological processpositive regulation of anoikis
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005730Cellular componentnucleolus
GO_0110016Cellular componentB-WICH complex
GO_0016020Cellular componentmembrane
GO_0005654Cellular componentnucleoplasm
GO_0042564Cellular componentNLS-dependent protein nuclear import complex
GO_0005737Cellular componentcytoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005634Cellular componentnucleus
GO_0043565Molecular functionsequence-specific DNA binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0003723Molecular functionRNA binding
GO_0070888Molecular functionE-box binding

IV. Literature review

[source]
Gene nameMYBBP1A
Protein nameMyb-binding protein 1A
MYB binding protein 1a
SynonymsP160
DescriptionFUNCTION: May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity). Has a role in rRNA biogenesis together with PWP1 . .

AccessionsENST00000572759.1
ENST00000573723.1
I3L311
I3L1L3
ENST00000254718.9 [Q9BQG0-1]
I3L2H8
Q9BQG0
ENST00000573116.5
ENST00000381556.6 [Q9BQG0-2]