CIR1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	24% ± 8%	Explore
fibroblast	22 studies	24% ± 9%	Explore
endothelial cell	21 studies	24% ± 8%	Explore
B cell	17 studies	23% ± 11%	Explore
ciliated cell	17 studies	47% ± 15%	Explore
smooth muscle cell	15 studies	19% ± 4%	Explore
CD8-positive, alpha-beta T cell	15 studies	23% ± 10%	Explore
classical monocyte	14 studies	24% ± 11%	Explore
CD4-positive, alpha-beta T cell	14 studies	23% ± 10%	Explore
regulatory T cell	13 studies	20% ± 4%	Explore
gamma-delta T cell	13 studies	24% ± 10%	Explore
macrophage	12 studies	22% ± 6%	Explore
pericyte	12 studies	22% ± 4%	Explore
T cell	11 studies	19% ± 3%	Explore
naive B cell	11 studies	22% ± 6%	Explore
non-classical monocyte	11 studies	28% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	24% ± 7%	Explore
memory B cell	11 studies	20% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	26% ± 8%	Explore
plasmacytoid dendritic cell	10 studies	22% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	23% ± 10%	Explore
mature NK T cell	9 studies	21% ± 4%	Explore
myofibroblast cell	8 studies	22% ± 3%	Explore
connective tissue cell	8 studies	23% ± 5%	Explore
monocyte	8 studies	20% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	25% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	25% ± 7%	Explore
conventional dendritic cell	7 studies	26% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	28% ± 14%	Explore
mucosal invariant T cell	7 studies	20% ± 3%	Explore
epithelial cell	7 studies	40% ± 20%	Explore
endothelial cell of lymphatic vessel	6 studies	21% ± 6%	Explore
neuron	6 studies	26% ± 10%	Explore
mesothelial cell	6 studies	24% ± 12%	Explore
microglial cell	6 studies	19% ± 4%	Explore
endothelial cell of vascular tree	6 studies	19% ± 3%	Explore
basal cell	6 studies	33% ± 14%	Explore
type I pneumocyte	6 studies	21% ± 5%	Explore
astrocyte	6 studies	28% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	20% ± 4%	Explore
oligodendrocyte	6 studies	24% ± 6%	Explore
oligodendrocyte precursor cell	6 studies	24% ± 8%	Explore
goblet cell	6 studies	29% ± 14%	Explore
mast cell	5 studies	19% ± 4%	Explore
neutrophil	5 studies	20% ± 3%	Explore
capillary endothelial cell	5 studies	18% ± 2%	Explore
abnormal cell	5 studies	24% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	25% ± 16%	Explore
innate lymphoid cell	5 studies	22% ± 5%	Explore
interneuron	5 studies	32% ± 21%	Explore
deuterosomal cell	4 studies	21% ± 2%	Explore
leukocyte	4 studies	26% ± 9%	Explore
endothelial cell of artery	4 studies	18% ± 1%	Explore
plasma cell	4 studies	29% ± 10%	Explore
club cell	4 studies	22% ± 4%	Explore
secretory cell	4 studies	27% ± 16%	Explore
GABAergic neuron	4 studies	43% ± 7%	Explore
glutamatergic neuron	4 studies	46% ± 18%	Explore
type B pancreatic cell	3 studies	33% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	23% ± 7%	Explore
exhausted T cell	3 studies	29% ± 15%	Explore
plasmablast	3 studies	38% ± 11%	Explore
glomerular endothelial cell	3 studies	21% ± 4%	Explore
progenitor cell	3 studies	18% ± 1%	Explore
neural crest cell	3 studies	19% ± 2%	Explore
precursor B cell	3 studies	28% ± 10%	Explore
pro-B cell	3 studies	24% ± 3%	Explore
amacrine cell	3 studies	32% ± 10%	Explore
retina horizontal cell	3 studies	23% ± 9%	Explore
retinal cone cell	3 studies	30% ± 8%	Explore
retinal rod cell	3 studies	26% ± 8%	Explore
lymphocyte	3 studies	25% ± 10%	Explore
Mueller cell	3 studies	26% ± 5%	Explore
rod bipolar cell	3 studies	21% ± 5%	Explore
dendritic cell	3 studies	46% ± 21%	Explore
pancreatic A cell	3 studies	26% ± 3%	Explore
granulocyte	3 studies	21% ± 5%	Explore
intestinal crypt stem cell	3 studies	18% ± 2%	Explore
T follicular helper cell	3 studies	20% ± 2%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	19% ± 2%	Explore
double negative thymocyte	3 studies	35% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	25% ± 11%	Explore
lung	11 studies	25% ± 11%	Explore
brain	8 studies	29% ± 14%	Explore
intestine	6 studies	21% ± 8%	Explore
eye	5 studies	26% ± 7%	Explore
pancreas	3 studies	26% ± 6%	Explore
kidney	3 studies	17% ± 0%	Explore
bone marrow	3 studies	17% ± 1%	Explore
uterus	3 studies	30% ± 14%	Explore
adipose	3 studies	17% ± 1%	Explore
liver	3 studies	32% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2052.17	2642 / 2642	100%	49.09	705 / 705
esophagus	100%	1952.06	1445 / 1445	100%	34.98	183 / 183
liver	100%	954.32	226 / 226	100%	25.65	406 / 406
ovary	100%	2332.62	180 / 180	100%	40.70	430 / 430
pancreas	100%	1239.01	328 / 328	100%	41.60	178 / 178
prostate	100%	2355.93	245 / 245	100%	44.52	502 / 502
thymus	100%	2286.93	653 / 653	100%	61.79	605 / 605
uterus	100%	2419.54	170 / 170	100%	43.72	459 / 459
lung	100%	2185.00	578 / 578	100%	43.97	1153 / 1155
stomach	100%	1631.57	359 / 359	100%	36.04	285 / 286
breast	100%	2395.46	459 / 459	100%	52.28	1114 / 1118
bladder	100%	2178.48	21 / 21	100%	38.62	502 / 504
adrenal gland	100%	1685.30	258 / 258	100%	42.83	229 / 230
kidney	100%	1608.85	89 / 89	99%	38.18	893 / 901
intestine	100%	2275.51	966 / 966	99%	38.80	520 / 527
skin	100%	2532.09	1809 / 1809	97%	37.52	458 / 472
adipose	100%	2240.41	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2233.30	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	48.39	29 / 29
spleen	100%	2740.07	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	38.89	45 / 45
ureter	0%	0	0 / 0	100%	28.34	1 / 1
muscle	100%	1604.15	802 / 803	0%	0	0 / 0
peripheral blood	99%	2987.12	924 / 929	0%	0	0 / 0
heart	99%	1277.72	854 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	84%	18.73	67 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008380	Biological process	RNA splicing
GO_0006397	Biological process	mRNA processing
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0001701	Biological process	in utero embryonic development
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0016607	Cellular component	nuclear speck
GO_0005813	Cellular component	centrosome
GO_0032991	Cellular component	protein-containing complex
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0044877	Molecular function	protein-containing complex binding
GO_0019901	Molecular function	protein kinase binding
GO_0003714	Molecular function	transcription corepressor activity
GO_0005515	Molecular function	protein binding
GO_0042826	Molecular function	histone deacetylase binding

IV. Literature review

[source]

Gene name	CIR1
Protein name	Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor) (Recepin) Corepressor interacting with RBPJ, CIR1
Synonyms	CIR
Description	FUNCTION: May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription. .
Accessions	Q86X95 H3BLY3 ENST00000342016.8 [Q86X95-1] ENST00000377973.4

CIR1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review