I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| type I pneumocyte | 6 studies | 20% ± 3% | |
| cardiac muscle cell | 6 studies | 74% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| type I pneumocyte | 6 studies | 20% ± 3% | |
| cardiac muscle cell | 6 studies | 74% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| heart | 6 studies | 28% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 81% | 5168.41 | 468 / 578 | 51% | 5.07 | 591 / 1155 |
| heart | 100% | 186306.14 | 858 / 861 | 0% | 0 | 0 / 0 |
| muscle | 97% | 28828.70 | 775 / 803 | 0% | 0 | 0 / 0 |
| pancreas | 2% | 20.28 | 6 / 328 | 76% | 12.14 | 136 / 178 |
| liver | 4% | 69.98 | 8 / 226 | 54% | 13.81 | 221 / 406 |
| prostate | 16% | 428.24 | 38 / 245 | 35% | 6.04 | 176 / 502 |
| kidney | 1% | 4.54 | 1 / 89 | 45% | 2.36 | 408 / 901 |
| skin | 26% | 1035.15 | 470 / 1809 | 10% | 1.06 | 48 / 472 |
| ovary | 3% | 16.58 | 5 / 180 | 31% | 1.35 | 135 / 430 |
| uterus | 1% | 9.81 | 1 / 170 | 29% | 4.08 | 134 / 459 |
| blood vessel | 28% | 895.11 | 372 / 1335 | 0% | 0 | 0 / 0 |
| breast | 2% | 138.43 | 11 / 459 | 23% | 2.11 | 257 / 1118 |
| bladder | 5% | 93.57 | 1 / 21 | 19% | 2.05 | 95 / 504 |
| tonsil | 0% | 0 | 0 / 0 | 20% | 8.41 | 9 / 45 |
| adrenal gland | 0% | 25.43 | 1 / 258 | 16% | 0.73 | 36 / 230 |
| thymus | 1% | 63.77 | 9 / 653 | 14% | 1.82 | 87 / 605 |
| intestine | 1% | 20.47 | 14 / 966 | 12% | 0.77 | 65 / 527 |
| stomach | 1% | 36.97 | 4 / 359 | 12% | 1.55 | 35 / 286 |
| esophagus | 2% | 96.29 | 25 / 1445 | 11% | 0.86 | 21 / 183 |
| brain | 1% | 7.81 | 16 / 2642 | 11% | 0.69 | 75 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.09 | 1 / 29 |
| spleen | 2% | 11.28 | 5 / 241 | 0% | 0 | 0 / 0 |
| adipose | 2% | 41.68 | 24 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 13.43 | 12 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.01 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0035994 | Biological process | response to muscle stretch |
| GO_0071560 | Biological process | cellular response to transforming growth factor beta stimulus |
| GO_0071466 | Biological process | cellular response to xenobiotic stimulus |
| GO_0071260 | Biological process | cellular response to mechanical stimulus |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0071347 | Biological process | cellular response to interleukin-1 |
| GO_0043517 | Biological process | positive regulation of DNA damage response, signal transduction by p53 class mediator |
| GO_0050714 | Biological process | positive regulation of protein secretion |
| GO_0055008 | Biological process | cardiac muscle tissue morphogenesis |
| GO_0071356 | Biological process | cellular response to tumor necrosis factor |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0045214 | Biological process | sarcomere organization |
| GO_0070528 | Biological process | protein kinase C signaling |
| GO_0035914 | Biological process | skeletal muscle cell differentiation |
| GO_2000279 | Biological process | negative regulation of DNA biosynthetic process |
| GO_0043065 | Biological process | positive regulation of apoptotic process |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0031674 | Cellular component | I band |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005667 | Cellular component | transcription regulator complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0070412 | Molecular function | R-SMAD binding |
| GO_0031432 | Molecular function | titin binding |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
| GO_0002039 | Molecular function | p53 binding |
| GO_0003713 | Molecular function | transcription coactivator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0042826 | Molecular function | histone deacetylase binding |
| Gene name | ANKRD1 |
| Protein name | Ankyrin repeat domain 1 (Cardiac muscle) (Epididymis secretory sperm binding protein) Ankyrin repeat domain 1 Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible gene C-193 protein) (Cytokine-inducible nuclear protein) ANKRD1 protein |
| Synonyms | CARP HA1A2 C193 hCG_1787896 |
| Description | FUNCTION: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. . |
| Accessions | A0A7R6M6R9 Q05DQ9 A0A384NYH5 ENST00000371697.4 Q15327 |
