Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 4 studies | 28% ± 6% | |
| glutamatergic neuron | 4 studies | 41% ± 15% | |
| endothelial cell | 3 studies | 23% ± 7% | |
| ciliated cell | 3 studies | 20% ± 1% | |
| GABAergic neuron | 3 studies | 45% ± 4% | |
| interneuron | 3 studies | 40% ± 18% | |
| neuron | 3 studies | 21% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 34% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 2977.67 | 180 / 180 | 99% | 13.86 | 424 / 430 |
| thymus | 100% | 3143.01 | 653 / 653 | 96% | 7.34 | 580 / 605 |
| brain | 96% | 1787.16 | 2543 / 2642 | 100% | 16.24 | 702 / 705 |
| breast | 100% | 1678.40 | 459 / 459 | 93% | 6.28 | 1043 / 1118 |
| esophagus | 100% | 1613.70 | 1445 / 1445 | 91% | 6.15 | 166 / 183 |
| prostate | 100% | 2111.22 | 245 / 245 | 90% | 5.39 | 451 / 502 |
| pancreas | 99% | 1021.55 | 324 / 328 | 91% | 4.95 | 162 / 178 |
| kidney | 100% | 1541.02 | 89 / 89 | 89% | 6.91 | 798 / 901 |
| skin | 93% | 748.53 | 1674 / 1809 | 96% | 8.13 | 452 / 472 |
| adrenal gland | 100% | 1245.68 | 258 / 258 | 86% | 5.81 | 197 / 230 |
| lung | 100% | 1482.67 | 578 / 578 | 85% | 4.51 | 980 / 1155 |
| bladder | 100% | 1830.52 | 21 / 21 | 74% | 3.79 | 375 / 504 |
| uterus | 100% | 3307.90 | 170 / 170 | 71% | 4.59 | 326 / 459 |
| stomach | 100% | 1247.17 | 358 / 359 | 70% | 3.47 | 199 / 286 |
| intestine | 99% | 1647.42 | 955 / 966 | 60% | 2.43 | 317 / 527 |
| spleen | 100% | 1470.80 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1937.62 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 1361.12 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 6.44 | 78 / 80 |
| heart | 95% | 903.95 | 818 / 861 | 0% | 0 | 0 / 0 |
| muscle | 95% | 635.93 | 759 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 62% | 2.76 | 28 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 55% | 2.71 | 16 / 29 |
| liver | 25% | 106.85 | 56 / 226 | 16% | 0.76 | 65 / 406 |
| peripheral blood | 36% | 217.93 | 335 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071300 | Biological process | cellular response to retinoic acid |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_1990830 | Biological process | cellular response to leukemia inhibitory factor |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0031519 | Cellular component | PcG protein complex |
| GO_0001739 | Cellular component | sex chromatin |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0035102 | Cellular component | PRC1 complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0042393 | Molecular function | histone binding |
| GO_0003682 | Molecular function | chromatin binding |
| Gene name | PHC1 |
| Protein name | Polyhomeotic homolog 1 (Drosophila) Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1) PHC1 protein Polyhomeotic homolog 1 |
| Synonyms | EDR1 PH1 |
| Description | FUNCTION: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression. . |
| Accessions | ENST00000433083.6 F5H6P9 F5H0T9 F5H6F5 ENST00000544916.6 ENST00000539063.5 ENST00000535510.1 H0YH74 ENST00000542346.1 ENST00000537610.1 ENST00000541181.1 F5H6F9 H0YGK7 ENST00000540574.5 Q6GMQ3 F5GZP4 ENST00000543824.5 ENST00000544539.5 B2RXH1 J3KQH6 P78364 ENST00000538657.5 H0YGZ1 |
