Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| microglial cell | 14 studies | 50% ± 15% | |
| smooth muscle cell | 10 studies | 33% ± 13% | |
| adipocyte | 10 studies | 50% ± 18% | |
| fibroblast | 10 studies | 35% ± 15% | |
| glutamatergic neuron | 9 studies | 42% ± 15% | |
| endothelial cell | 8 studies | 33% ± 14% | |
| endothelial cell of lymphatic vessel | 6 studies | 48% ± 13% | |
| ciliated cell | 6 studies | 51% ± 23% | |
| myofibroblast cell | 5 studies | 43% ± 11% | |
| Mueller cell | 5 studies | 72% ± 29% | |
| astrocyte | 5 studies | 53% ± 21% | |
| basal cell | 5 studies | 48% ± 21% | |
| type II pneumocyte | 5 studies | 56% ± 10% | |
| hepatocyte | 4 studies | 55% ± 25% | |
| epithelial cell | 4 studies | 38% ± 22% | |
| cardiac muscle cell | 4 studies | 16% ± 1% | |
| club cell | 4 studies | 28% ± 12% | |
| cholangiocyte | 3 studies | 44% ± 20% | |
| neuron | 3 studies | 25% ± 4% | |
| interneuron | 3 studies | 28% ± 14% | |
| progenitor cell | 3 studies | 32% ± 8% | |
| respiratory goblet cell | 3 studies | 50% ± 22% | |
| GABAergic neuron | 3 studies | 38% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2001.24 | 1444 / 1445 | 58% | 2.57 | 106 / 183 |
| thymus | 100% | 1235.89 | 650 / 653 | 39% | 1.11 | 237 / 605 |
| lung | 80% | 342.65 | 465 / 578 | 58% | 1.94 | 667 / 1155 |
| uterus | 100% | 2114.33 | 170 / 170 | 37% | 1.12 | 168 / 459 |
| pancreas | 100% | 604.41 | 327 / 328 | 37% | 0.94 | 65 / 178 |
| intestine | 99% | 3463.37 | 961 / 966 | 33% | 0.78 | 173 / 527 |
| bladder | 100% | 1827.43 | 21 / 21 | 30% | 0.75 | 149 / 504 |
| prostate | 87% | 595.04 | 212 / 245 | 30% | 0.47 | 151 / 502 |
| stomach | 77% | 1113.81 | 278 / 359 | 33% | 1.21 | 93 / 286 |
| breast | 96% | 604.38 | 440 / 459 | 13% | 0.27 | 143 / 1118 |
| skin | 88% | 849.28 | 1594 / 1809 | 19% | 0.56 | 88 / 472 |
| ovary | 99% | 1157.64 | 179 / 180 | 3% | 0.10 | 15 / 430 |
| kidney | 37% | 166.91 | 33 / 89 | 65% | 2.54 | 582 / 901 |
| liver | 81% | 309.11 | 183 / 226 | 18% | 0.34 | 74 / 406 |
| brain | 51% | 303.47 | 1350 / 2642 | 41% | 1.19 | 286 / 705 |
| adipose | 91% | 523.20 | 1099 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 90% | 533.75 | 721 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 87% | 643.43 | 1160 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 70% | 267.46 | 181 / 258 | 5% | 0.18 | 12 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 73% | 3.07 | 33 / 45 |
| heart | 48% | 169.00 | 415 / 861 | 0% | 0 | 0 / 0 |
| spleen | 23% | 65.05 | 55 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.09 | 1 / 29 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.10 | 1 / 80 |
| peripheral blood | 0% | 1.29 | 3 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0021987 | Biological process | cerebral cortex development |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0021757 | Biological process | caudate nucleus development |
| GO_0021758 | Biological process | putamen development |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | FOXP2 |
| Protein name | Forkhead box protein P2 Forkhead box P2 isoform C Forkhead box P2 Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat-containing gene 10 protein) Forkhead box P2 isoform A Forkhead box P2 (Forkhead/winged helix transcription factor) Forkhead/winged helix transcription factor Forkhead transcription factor |
| Synonyms | TNRC10 tcag7.56 hCG_1813384 CAGH44 |
| Description | FUNCTION: Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language. |
| Accessions | ENST00000634623.1 ENST00000635109.1 [O15409-8] A0A994J6W1 B7ZLK5 Q0PRL4 ENST00000393489.8 [O15409-8] ENST00000452963.6 ENST00000350908.9 [O15409-1] Q8N6B6 ENST00000703616.1 ENST00000378237.7 [O15409-7] A0A0U1RQE6 A8MTU2 A0A0U1RQY3 C9JQP8 X5D7Z0 ENST00000703612.1 ENST00000441290.6 [O15409-8] ENST00000703614.1 [O15409-1] Q75MZ5 ENST00000393494.6 [O15409-1] A4D0T4 ENST00000703618.1 ENST00000393498.6 ENST00000703617.1 A0A0U1RQM2 X5D2H2 ENST00000462331.5 ENST00000390668.3 Q8N6B5 O15409 ENST00000403559.9 [O15409-9] A0A0U1RQR8 ENST00000635534.1 ENST00000440349.5 F8WDL6 ENST00000360232.8 [O15409-6] A0A0U1RQE0 ENST00000634411.1 ENST00000703615.1 ENST00000635638.1 A0A994J6H2 ENST00000635563.1 ENST00000408937.7 [O15409-4] ENST00000412402.5 [O15409-8] X5D9N5 A8MUV4 ENST00000703613.1 [O15409-9] ENST00000393495.7 Q8NFT3 A0A994J3Y0 |