FOXP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0021987Biological processcerebral cortex development
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0021757Biological processcaudate nucleus development
GO_0021758Biological processputamen development
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0042803Molecular functionprotein homodimerization activity
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding
GO_0046872Molecular functionmetal ion binding
GO_0042802Molecular functionidentical protein binding

IV. Literature review

[source]
Gene nameFOXP2
Protein nameForkhead box protein P2
Forkhead box P2 isoform C
Forkhead box P2
Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat-containing gene 10 protein)
Forkhead box P2 isoform A
Forkhead box P2 (Forkhead/winged helix transcription factor)
Forkhead/winged helix transcription factor
Forkhead transcription factor
SynonymsTNRC10
tcag7.56
hCG_1813384
CAGH44
DescriptionFUNCTION: Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.

AccessionsENST00000634623.1
ENST00000635109.1 [O15409-8]
A0A994J6W1
B7ZLK5
Q0PRL4
ENST00000393489.8 [O15409-8]
ENST00000452963.6
ENST00000350908.9 [O15409-1]
Q8N6B6
ENST00000703616.1
ENST00000378237.7 [O15409-7]
A0A0U1RQE6
A8MTU2
A0A0U1RQY3
C9JQP8
X5D7Z0
ENST00000703612.1
ENST00000441290.6 [O15409-8]
ENST00000703614.1 [O15409-1]
Q75MZ5
ENST00000393494.6 [O15409-1]
A4D0T4
ENST00000703618.1
ENST00000393498.6
ENST00000703617.1
A0A0U1RQM2
X5D2H2
ENST00000462331.5
ENST00000390668.3
Q8N6B5
O15409
ENST00000403559.9 [O15409-9]
A0A0U1RQR8
ENST00000635534.1
ENST00000440349.5
F8WDL6
ENST00000360232.8 [O15409-6]
A0A0U1RQE0
ENST00000634411.1
ENST00000703615.1
ENST00000635638.1
A0A994J6H2
ENST00000635563.1
ENST00000408937.7 [O15409-4]
ENST00000412402.5 [O15409-8]
X5D9N5
A8MUV4
ENST00000703613.1 [O15409-9]
ENST00000393495.7
Q8NFT3
A0A994J3Y0