ZNF282 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZNF282 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZNF282 at tissue level.

III. Associated gene sets

GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameZNF282
Protein nameZinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1)
Zinc finger protein 282
ZNF282 protein
Synonymstcag7.517
HUB1
DescriptionFUNCTION: Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. It recognizes the 5'-TCCACCCC-3' sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression.

AccessionsA0A090N8Y3
Q9UDV7
ENST00000479907.1 [Q9UDV7-2]
ENST00000610704.5 [Q9UDV7-1]
Q05BY5
Q7Z2V4