SCML4 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	22 studies	25% ± 9%	Explore
CD8-positive, alpha-beta T cell	18 studies	25% ± 7%	Explore
T cell	14 studies	28% ± 8%	Explore
natural killer cell	14 studies	22% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	24% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	26% ± 10%	Explore
gamma-delta T cell	10 studies	29% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	28% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	27% ± 4%	Explore
mucosal invariant T cell	8 studies	23% ± 7%	Explore
mature NK T cell	8 studies	22% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	21% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	28% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	23% ± 7%	Explore
innate lymphoid cell	4 studies	23% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	26% ± 3%	Explore
T follicular helper cell	3 studies	28% ± 6%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 3%	Explore
lymphocyte	3 studies	41% ± 10%	Explore
interneuron	3 studies	24% ± 4%	Explore

II. Expression across tissues

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
stomach	82%	122.13	295 / 359	51%	1.39	146 / 286
lung	99%	241.66	575 / 578	29%	0.64	339 / 1155
liver	96%	135.42	216 / 226	23%	0.50	93 / 406
intestine	67%	331.56	650 / 966	44%	1.26	232 / 527
pancreas	77%	55.88	252 / 328	34%	0.80	60 / 178
thymus	84%	124.22	551 / 653	20%	0.69	124 / 605
spleen	100%	1017.08	241 / 241	0%	0	0 / 0
skin	36%	26.32	658 / 1809	56%	5.00	265 / 472
peripheral blood	88%	550.15	819 / 929	0%	0	0 / 0
kidney	65%	86.88	58 / 89	19%	0.32	167 / 901
bladder	62%	116.52	13 / 21	21%	0.53	104 / 504
prostate	76%	90.98	187 / 245	6%	0.12	28 / 502
lymph node	0%	0	0 / 0	76%	2.35	22 / 29
adrenal gland	27%	20.06	69 / 258	47%	1.35	108 / 230
adipose	71%	62.25	857 / 1204	0%	0	0 / 0
breast	49%	48.32	225 / 459	21%	0.52	240 / 1118
uterus	53%	32.78	90 / 170	15%	0.34	71 / 459
esophagus	46%	38.93	666 / 1445	16%	0.35	30 / 183
tonsil	0%	0	0 / 0	49%	0.94	22 / 45
blood vessel	24%	21.68	315 / 1335	0%	0	0 / 0
ovary	19%	13.22	34 / 180	3%	0.10	11 / 430
brain	12%	6.65	315 / 2642	3%	0.07	20 / 705
heart	11%	6.54	92 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	3%	0.04	2 / 80
muscle	1%	0.68	7 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1