PRDM8 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRDM8 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	4388.26	245 / 245	97%	15.92	485 / 502
brain	82%	1178.42	2165 / 2642	90%	9.04	638 / 705
esophagus	83%	1777.60	1193 / 1445	81%	3.01	149 / 183
uterus	99%	1668.88	169 / 170	59%	2.33	272 / 459
bladder	100%	1660.62	21 / 21	58%	2.15	294 / 504
intestine	95%	1333.41	914 / 966	62%	2.70	325 / 527
breast	96%	752.21	439 / 459	45%	0.86	499 / 1118
lung	66%	229.63	380 / 578	71%	2.53	822 / 1155
stomach	66%	749.57	237 / 359	64%	2.26	182 / 286
ovary	98%	872.83	177 / 180	21%	0.38	92 / 430
skin	81%	565.67	1474 / 1809	34%	1.72	162 / 472
ureter	0%	0	0 / 0	100%	1.03	1 / 1
pancreas	6%	14.64	19 / 328	91%	4.64	162 / 178
adipose	95%	694.04	1147 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	90%	4.37	26 / 29
blood vessel	84%	461.76	1116 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	82%	1.69	37 / 45
adrenal gland	17%	76.53	45 / 258	63%	10.21	146 / 230
spleen	80%	277.51	192 / 241	0%	0	0 / 0
thymus	43%	157.15	279 / 653	24%	0.70	143 / 605
kidney	22%	107.49	20 / 89	36%	1.21	325 / 901
peripheral blood	57%	268.42	526 / 929	0%	0	0 / 0
heart	36%	111.74	312 / 861	0%	0	0 / 0
muscle	33%	113.40	266 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	8%	0.66	6 / 80
liver	0%	0	0 / 226	4%	0.13	18 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006338	Biological process	chromatin remodeling
GO_0014003	Biological process	oligodendrocyte development
GO_0021540	Biological process	corpus callosum morphogenesis
GO_0021957	Biological process	corticospinal tract morphogenesis
GO_0032259	Biological process	methylation
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0006355	Biological process	regulation of DNA-templated transcription
GO_0016604	Cellular component	nuclear body
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0003714	Molecular function	transcription corepressor activity
GO_0046974	Molecular function	histone H3K9 methyltransferase activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding
GO_0003682	Molecular function	chromatin binding

Gene name	PRDM8
Protein name	PR domain zinc finger protein 8 (EC 2.1.1.-) (PR domain-containing protein 8) PRDM8 protein PR/SET domain 8
Synonyms	PFM5
Description	FUNCTION: Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity). .
Accessions	ENST00000415738.3 [Q9NQV8-1] E9PEH0 Q9NQV8 Q05CA1 ENST00000515013.5 ENST00000504452.5 [Q9NQV8-1] ENST00000339711.8 [Q9NQV8-1]

PRDM8 report