ZNF148 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	28 studies	34% ± 13%	Explore
astrocyte	18 studies	35% ± 18%	Explore
fibroblast	16 studies	27% ± 10%	Explore
B cell	15 studies	22% ± 7%	Explore
natural killer cell	15 studies	22% ± 6%	Explore
microglial cell	15 studies	46% ± 14%	Explore
smooth muscle cell	14 studies	25% ± 8%	Explore
pericyte	14 studies	26% ± 8%	Explore
macrophage	13 studies	35% ± 14%	Explore
oligodendrocyte	13 studies	35% ± 13%	Explore
oligodendrocyte precursor cell	13 studies	40% ± 18%	Explore
glutamatergic neuron	12 studies	53% ± 25%	Explore
GABAergic neuron	11 studies	50% ± 23%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	20% ± 4%	Explore
endothelial cell of lymphatic vessel	10 studies	30% ± 13%	Explore
type I pneumocyte	9 studies	27% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	20% ± 3%	Explore
epithelial cell	9 studies	39% ± 18%	Explore
adipocyte	9 studies	37% ± 9%	Explore
naive B cell	8 studies	19% ± 2%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	19% ± 4%	Explore
basal cell	8 studies	31% ± 18%	Explore
mast cell	8 studies	27% ± 7%	Explore
CD4-positive, alpha-beta T cell	7 studies	22% ± 3%	Explore
neuron	7 studies	45% ± 19%	Explore
CD8-positive, alpha-beta T cell	7 studies	21% ± 3%	Explore
myeloid cell	7 studies	31% ± 4%	Explore
ciliated cell	7 studies	25% ± 8%	Explore
T cell	6 studies	25% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	20% ± 3%	Explore
interneuron	6 studies	59% ± 23%	Explore
myofibroblast cell	6 studies	23% ± 9%	Explore
club cell	6 studies	31% ± 11%	Explore
retina horizontal cell	6 studies	35% ± 12%	Explore
dendritic cell	6 studies	30% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	19% ± 2%	Explore
memory B cell	6 studies	17% ± 1%	Explore
monocyte	6 studies	30% ± 10%	Explore
classical monocyte	5 studies	20% ± 5%	Explore
mature NK T cell	5 studies	21% ± 8%	Explore
retinal bipolar neuron	5 studies	25% ± 8%	Explore
retinal ganglion cell	5 studies	33% ± 11%	Explore
mucosal invariant T cell	5 studies	18% ± 3%	Explore
amacrine cell	5 studies	33% ± 9%	Explore
retinal cone cell	5 studies	24% ± 10%	Explore
retinal rod cell	5 studies	28% ± 9%	Explore
cardiac muscle cell	5 studies	41% ± 9%	Explore
abnormal cell	5 studies	27% ± 16%	Explore
endothelial cell of vascular tree	5 studies	27% ± 13%	Explore
regulatory T cell	5 studies	19% ± 3%	Explore
type II pneumocyte	5 studies	30% ± 10%	Explore
connective tissue cell	5 studies	24% ± 7%	Explore
goblet cell	5 studies	32% ± 25%	Explore
gamma-delta T cell	5 studies	21% ± 7%	Explore
leukocyte	4 studies	32% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
non-classical monocyte	4 studies	21% ± 7%	Explore
granule cell	4 studies	35% ± 9%	Explore
retinal pigment epithelial cell	4 studies	31% ± 21%	Explore
mesothelial cell	4 studies	34% ± 9%	Explore
lymphocyte	4 studies	35% ± 9%	Explore
Mueller cell	4 studies	28% ± 10%	Explore
respiratory goblet cell	4 studies	31% ± 16%	Explore
glomerular endothelial cell	3 studies	17% ± 1%	Explore
GABAergic interneuron	3 studies	44% ± 7%	Explore
glial cell	3 studies	27% ± 2%	Explore
progenitor cell	3 studies	31% ± 4%	Explore
plasma cell	3 studies	29% ± 2%	Explore
brush cell	3 studies	28% ± 5%	Explore
mononuclear phagocyte	3 studies	29% ± 7%	Explore
vein endothelial cell	3 studies	30% ± 14%	Explore
GABAergic amacrine cell	3 studies	36% ± 7%	Explore
OFF-bipolar cell	3 studies	31% ± 10%	Explore
ON-bipolar cell	3 studies	31% ± 9%	Explore
glycinergic amacrine cell	3 studies	30% ± 7%	Explore
rod bipolar cell	3 studies	34% ± 11%	Explore
secretory cell	3 studies	18% ± 1%	Explore
hepatocyte	3 studies	44% ± 19%	Explore
muscle cell	3 studies	35% ± 24%	Explore
ependymal cell	3 studies	36% ± 9%	Explore
enteroendocrine cell	3 studies	24% ± 5%	Explore
intestinal crypt stem cell	3 studies	19% ± 4%	Explore
adventitial cell	3 studies	19% ± 5%	Explore
alveolar macrophage	3 studies	41% ± 12%	Explore
capillary endothelial cell	3 studies	28% ± 6%	Explore
T follicular helper cell	3 studies	16% ± 1%	Explore
transit amplifying cell	3 studies	39% ± 30%	Explore
plasmacytoid dendritic cell	3 studies	21% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	20% ± 4%	Explore
mural cell	3 studies	41% ± 7%	Explore
mucus secreting cell	3 studies	32% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	43% ± 21%	Explore
lung	9 studies	24% ± 8%	Explore
eye	7 studies	32% ± 15%	Explore
peripheral blood	4 studies	22% ± 4%	Explore
heart	4 studies	33% ± 5%	Explore
liver	4 studies	33% ± 16%	Explore
adipose	4 studies	31% ± 10%	Explore
intestine	3 studies	22% ± 6%	Explore
kidney	3 studies	27% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2191.55	1445 / 1445	100%	24.48	183 / 183
lung	100%	2293.11	578 / 578	100%	19.29	1155 / 1155
ovary	100%	2645.97	180 / 180	100%	19.25	430 / 430
brain	100%	1757.81	2636 / 2642	100%	18.89	705 / 705
breast	100%	2515.82	459 / 459	99%	24.14	1112 / 1118
pancreas	100%	1220.87	328 / 328	99%	14.20	177 / 178
prostate	100%	2309.74	245 / 245	99%	18.56	498 / 502
thymus	100%	3788.93	653 / 653	99%	25.13	600 / 605
uterus	100%	2797.70	170 / 170	99%	16.56	453 / 459
bladder	100%	2399.14	21 / 21	98%	14.09	494 / 504
stomach	100%	1585.69	359 / 359	98%	16.30	279 / 286
kidney	100%	1722.45	89 / 89	97%	18.86	875 / 901
intestine	100%	2399.60	966 / 966	97%	13.87	511 / 527
adrenal gland	100%	2316.11	258 / 258	89%	8.74	205 / 230
liver	100%	1254.04	226 / 226	86%	8.14	350 / 406
skin	100%	2459.53	1806 / 1809	86%	12.30	404 / 472
blood vessel	100%	3243.10	1335 / 1335	0%	0	0 / 0
muscle	100%	1871.94	803 / 803	0%	0	0 / 0
spleen	100%	2062.73	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	20.41	45 / 45
ureter	0%	0	0 / 0	100%	4.54	1 / 1
adipose	100%	2579.26	1203 / 1204	0%	0	0 / 0
heart	98%	1564.26	844 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	11.45	28 / 29
peripheral blood	87%	1984.31	812 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	45%	3.41	36 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007276	Biological process	gamete generation
GO_0010629	Biological process	negative regulation of gene expression
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0006968	Biological process	cellular defense response
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0021762	Biological process	substantia nigra development
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0005794	Cellular component	Golgi apparatus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0005515	Molecular function	protein binding
GO_0001227	Molecular function	DNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0043565	Molecular function	sequence-specific DNA binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	ZNF148
Protein name	ZNF148 protein Zinc finger protein Zinc finger protein 148 ZBP-89 delta-Nter isoform Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89)
Synonyms	hCG_16464 ZBP89
Description	FUNCTION: Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.
Accessions	C9K0U4 C9JRX0 ENST00000471196.2 [Q9UQR1-1] C9J6Y6 ENST00000495019.5 ENST00000484491.5 [Q9UQR1-1] ENST00000700044.1 [Q9UQR1-1] ENST00000465763.5 ENST00000471196.1 ENST00000468369.5 ENST00000360647.9 [Q9UQR1-1] ENST00000492394.5 [Q9UQR1-1] Q12900 Q8IWK7 Q4FD37 G5E9X2 Q9UQR1 ENST00000485866.5 [Q9UQR1-1]

ZNF148 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review