Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 17 studies | 25% ± 9% | |
endothelial cell of lymphatic vessel | 10 studies | 22% ± 6% | |
non-classical monocyte | 8 studies | 27% ± 14% | |
classical monocyte | 6 studies | 24% ± 11% | |
capillary endothelial cell | 6 studies | 21% ± 3% | |
vein endothelial cell | 4 studies | 22% ± 6% | |
macrophage | 4 studies | 19% ± 3% | |
glomerular endothelial cell | 3 studies | 17% ± 2% | |
endothelial cell of vascular tree | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 100% | 3266.90 | 1809 / 1809 | 100% | 32.70 | 472 / 472 |
thymus | 100% | 3011.41 | 652 / 653 | 100% | 12.14 | 604 / 605 |
esophagus | 100% | 3895.78 | 1445 / 1445 | 99% | 10.83 | 182 / 183 |
prostate | 100% | 3916.13 | 245 / 245 | 99% | 10.81 | 499 / 502 |
brain | 99% | 2677.89 | 2622 / 2642 | 100% | 15.40 | 705 / 705 |
breast | 100% | 4232.67 | 459 / 459 | 99% | 11.38 | 1107 / 1118 |
uterus | 100% | 4830.75 | 170 / 170 | 99% | 14.31 | 454 / 459 |
kidney | 100% | 3214.40 | 89 / 89 | 98% | 17.07 | 887 / 901 |
bladder | 100% | 5062.29 | 21 / 21 | 98% | 11.29 | 496 / 504 |
intestine | 100% | 3344.19 | 965 / 966 | 98% | 9.00 | 516 / 527 |
lung | 100% | 6111.30 | 578 / 578 | 98% | 11.92 | 1128 / 1155 |
adrenal gland | 100% | 3941.18 | 258 / 258 | 97% | 16.78 | 223 / 230 |
stomach | 99% | 2249.88 | 356 / 359 | 97% | 8.95 | 278 / 286 |
pancreas | 98% | 1527.11 | 320 / 328 | 98% | 12.07 | 175 / 178 |
ovary | 100% | 2379.48 | 180 / 180 | 78% | 5.00 | 336 / 430 |
liver | 69% | 875.96 | 156 / 226 | 96% | 8.29 | 389 / 406 |
adipose | 100% | 4196.16 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 26.09 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 13.38 | 29 / 29 |
spleen | 100% | 8434.29 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 14.09 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.60 | 1 / 1 |
blood vessel | 100% | 2625.74 | 1330 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 2129.41 | 857 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 7746.47 | 910 / 929 | 0% | 0 | 0 / 0 |
muscle | 90% | 1167.96 | 724 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051224 | Biological process | negative regulation of protein transport |
GO_0071466 | Biological process | cellular response to xenobiotic stimulus |
GO_0045927 | Biological process | positive regulation of growth |
GO_0006469 | Biological process | negative regulation of protein kinase activity |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0044387 | Biological process | negative regulation of protein kinase activity by regulation of protein phosphorylation |
GO_0051496 | Biological process | positive regulation of stress fiber assembly |
GO_0050921 | Biological process | positive regulation of chemotaxis |
GO_0010811 | Biological process | positive regulation of cell-substrate adhesion |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0032880 | Biological process | regulation of protein localization |
GO_0035970 | Biological process | peptidyl-threonine dephosphorylation |
GO_0043280 | Biological process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
GO_0097193 | Biological process | intrinsic apoptotic signaling pathway |
GO_0070262 | Biological process | peptidyl-serine dephosphorylation |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0051894 | Biological process | positive regulation of focal adhesion assembly |
GO_0033137 | Biological process | negative regulation of peptidyl-serine phosphorylation |
GO_2000048 | Biological process | negative regulation of cell-cell adhesion mediated by cadherin |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0010634 | Biological process | positive regulation of epithelial cell migration |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0017018 | Molecular function | myosin phosphatase activity |
GO_0008138 | Molecular function | protein tyrosine/serine/threonine phosphatase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0004722 | Molecular function | protein serine/threonine phosphatase activity |
GO_0033192 | Molecular function | calmodulin-dependent protein phosphatase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | PPM1F |
Protein name | Protein phosphatase 1F (PP2C domain containing), isoform CRA_a (Protein phosphatase, Mg2+/Mn2+ dependent 1F) Protein phosphatase 1F (PP2C domain containing), isoform CRA_b (Protein phosphatase, Mg2+/Mn2+ dependent 1F) Protein phosphatase 1F (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (Protein fem-2 homolog) (hFem-2) PPM1F protein Protein phosphatase, Mg2+/Mn2+ dependent 1F Protein phosphatase 1F (PP2C domain containing) |
Synonyms | POPX2 KIAA0015 hCG_26717 |
Description | FUNCTION: Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis. |
Accessions | Q0VGL7 ENST00000407142.5 ENST00000445205.1 B5MCT7 ENST00000424647.1 P49593 C9JL74 Q6IPC0 C9J2F3 ENST00000263212.10 [P49593-1] A8MX49 ENST00000397495.8 |