PPM1F report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051224Biological processnegative regulation of protein transport
GO_0071466Biological processcellular response to xenobiotic stimulus
GO_0045927Biological processpositive regulation of growth
GO_0006469Biological processnegative regulation of protein kinase activity
GO_0006470Biological processprotein dephosphorylation
GO_0044387Biological processnegative regulation of protein kinase activity by regulation of protein phosphorylation
GO_0051496Biological processpositive regulation of stress fiber assembly
GO_0050921Biological processpositive regulation of chemotaxis
GO_0010811Biological processpositive regulation of cell-substrate adhesion
GO_0010628Biological processpositive regulation of gene expression
GO_0032880Biological processregulation of protein localization
GO_0035970Biological processpeptidyl-threonine dephosphorylation
GO_0043280Biological processpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO_0097193Biological processintrinsic apoptotic signaling pathway
GO_0070262Biological processpeptidyl-serine dephosphorylation
GO_0030335Biological processpositive regulation of cell migration
GO_0051894Biological processpositive regulation of focal adhesion assembly
GO_0033137Biological processnegative regulation of peptidyl-serine phosphorylation
GO_2000048Biological processnegative regulation of cell-cell adhesion mediated by cadherin
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0010634Biological processpositive regulation of epithelial cell migration
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0032991Cellular componentprotein-containing complex
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0017018Molecular functionmyosin phosphatase activity
GO_0008138Molecular functionprotein tyrosine/serine/threonine phosphatase activity
GO_0046872Molecular functionmetal ion binding
GO_0004722Molecular functionprotein serine/threonine phosphatase activity
GO_0033192Molecular functioncalmodulin-dependent protein phosphatase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePPM1F
Protein nameProtein phosphatase 1F (PP2C domain containing), isoform CRA_a (Protein phosphatase, Mg2+/Mn2+ dependent 1F)
Protein phosphatase 1F (PP2C domain containing), isoform CRA_b (Protein phosphatase, Mg2+/Mn2+ dependent 1F)
Protein phosphatase 1F (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (Protein fem-2 homolog) (hFem-2)
PPM1F protein
Protein phosphatase, Mg2+/Mn2+ dependent 1F
Protein phosphatase 1F (PP2C domain containing)
SynonymsPOPX2
KIAA0015
hCG_26717
DescriptionFUNCTION: Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis.

AccessionsQ0VGL7
ENST00000407142.5
ENST00000445205.1
B5MCT7
ENST00000424647.1
P49593
C9JL74
Q6IPC0
C9J2F3
ENST00000263212.10 [P49593-1]
A8MX49
ENST00000397495.8