TCEAL7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032088Biological processnegative regulation of NF-kappaB transcription factor activity
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus

IV. Literature review

[source]
Gene nameTCEAL7
Protein nameTranscription elongation factor A protein-like 7 (TCEA-like protein 7) (Transcription elongation factor S-II protein-like 7)
Synonyms
DescriptionFUNCTION: Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines. .

AccessionsQ9BRU2
ENST00000372666.1
ENST00000332431.5