HINFP report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HINFP at tissue level.

III. Associated gene sets

GO_0006281Biological processDNA repair
GO_0001701Biological processin utero embryonic development
GO_0010629Biological processnegative regulation of gene expression
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0045184Biological processestablishment of protein localization
GO_0010628Biological processpositive regulation of gene expression
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006351Biological processDNA-templated transcription
GO_0044843Biological processcell cycle G1/S phase transition
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0045445Biological processmyoblast differentiation
GO_0006355Biological processregulation of DNA-templated transcription
GO_0048856Biological processanatomical structure development
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0000082Biological processG1/S transition of mitotic cell cycle
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0000077Biological processDNA damage checkpoint signaling
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0015030Cellular componentCajal body
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0019899Molecular functionenzyme binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0042393Molecular functionhistone binding
GO_0003682Molecular functionchromatin binding
GO_0000976Molecular functiontranscription cis-regulatory region binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameHINFP
Protein nameHistone H4 transcription factor
Histone H4 transcription factor (Histone nuclear factor P) (HiNF-P) (MBD2-interacting zinc finger protein) (Methyl-CpG-binding protein 2-interacting zinc finger protein)
SynonymsMIZF
ZNF743
DescriptionFUNCTION: Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter. .

AccessionsQ9BQA5
E9PL67
ENST00000350777.7 [Q9BQA5-1]
ENST00000530678.1
ENST00000527410.3 [Q9BQA5-2]
ENST00000529988.5
E9PJA3