Insufficient scRNA-seq data for expression of TBL1Y at single-cell level.
Insufficient scRNA-seq data for expression of TBL1Y at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 96% | 123.15 | 235 / 245 | 97% | 5.82 | 486 / 502 |
thymus | 66% | 237.01 | 434 / 653 | 21% | 0.82 | 125 / 605 |
kidney | 78% | 50.48 | 69 / 89 | 5% | 0.09 | 42 / 901 |
liver | 68% | 29.66 | 153 / 226 | 11% | 0.24 | 46 / 406 |
pancreas | 63% | 36.93 | 206 / 328 | 3% | 0.05 | 5 / 178 |
bladder | 48% | 19.86 | 10 / 21 | 17% | 0.57 | 86 / 504 |
adipose | 59% | 35.89 | 713 / 1204 | 0% | 0 | 0 / 0 |
muscle | 59% | 32.22 | 474 / 803 | 0% | 0 | 0 / 0 |
breast | 59% | 50.78 | 270 / 459 | 0% | 0.00 | 2 / 1118 |
lung | 42% | 13.55 | 241 / 578 | 17% | 0.53 | 194 / 1155 |
stomach | 49% | 25.69 | 177 / 359 | 2% | 0.04 | 6 / 286 |
esophagus | 38% | 16.25 | 544 / 1445 | 14% | 0.53 | 25 / 183 |
skin | 45% | 19.01 | 820 / 1809 | 5% | 0.11 | 24 / 472 |
tonsil | 0% | 0 | 0 / 0 | 36% | 1.32 | 16 / 45 |
intestine | 18% | 3.74 | 171 / 966 | 5% | 0.09 | 24 / 527 |
brain | 21% | 4.67 | 550 / 2642 | 1% | 0.03 | 10 / 705 |
blood vessel | 19% | 4.42 | 255 / 1335 | 0% | 0 | 0 / 0 |
adrenal gland | 7% | 1.31 | 19 / 258 | 1% | 0.03 | 3 / 230 |
heart | 5% | 0.93 | 40 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.12 | 1 / 29 |
peripheral blood | 2% | 1.01 | 18 / 929 | 0% | 0 | 0 / 0 |
uterus | 0% | 0 | 0 / 170 | 0% | 0.03 | 2 / 459 |
spleen | 0% | 0.05 | 1 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0048545 | Biological process | response to steroid hormone |
GO_0043627 | Biological process | response to estrogen |
GO_0045444 | Biological process | fat cell differentiation |
GO_0050821 | Biological process | protein stabilization |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0000118 | Cellular component | histone deacetylase complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005667 | Cellular component | transcription regulator complex |
GO_0005634 | Cellular component | nucleus |
GO_0003714 | Molecular function | transcription corepressor activity |
GO_0005515 | Molecular function | protein binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
GO_0003682 | Molecular function | chromatin binding |
Gene name | TBL1Y |
Protein name | Transducin beta like 1 Y-linked F-box-like/WD repeat-containing protein TBL1Y (Transducin beta-like protein 1Y) (Transducin-beta-like protein 1, Y-linked) |
Synonyms | TBL1 |
Description | FUNCTION: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (By similarity). . |
Accessions | ENST00000651523.1 Q9BQ87 ENST00000383032.6 ENST00000346432.3 A0A494C153 ENST00000355162.6 |