RERE | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	39 studies	48% ± 22%	Explore
fibroblast	24 studies	42% ± 21%	Explore
smooth muscle cell	23 studies	34% ± 19%	Explore
astrocyte	20 studies	62% ± 20%	Explore
pericyte	19 studies	37% ± 20%	Explore
macrophage	18 studies	45% ± 23%	Explore
B cell	16 studies	35% ± 18%	Explore
microglial cell	16 studies	67% ± 18%	Explore
ciliated cell	15 studies	38% ± 20%	Explore
oligodendrocyte	15 studies	72% ± 15%	Explore
oligodendrocyte precursor cell	15 studies	68% ± 20%	Explore
mast cell	14 studies	37% ± 17%	Explore
endothelial cell of lymphatic vessel	13 studies	44% ± 23%	Explore
glutamatergic neuron	12 studies	76% ± 19%	Explore
epithelial cell	12 studies	45% ± 26%	Explore
basal cell	11 studies	44% ± 26%	Explore
naive B cell	11 studies	24% ± 6%	Explore
GABAergic neuron	11 studies	76% ± 21%	Explore
adipocyte	11 studies	64% ± 23%	Explore
type I pneumocyte	10 studies	43% ± 24%	Explore
capillary endothelial cell	10 studies	30% ± 15%	Explore
club cell	9 studies	45% ± 26%	Explore
neuron	9 studies	55% ± 27%	Explore
vein endothelial cell	9 studies	41% ± 26%	Explore
myeloid cell	9 studies	40% ± 20%	Explore
amacrine cell	8 studies	65% ± 23%	Explore
mesothelial cell	8 studies	49% ± 18%	Explore
plasmacytoid dendritic cell	8 studies	21% ± 5%	Explore
retinal ganglion cell	7 studies	66% ± 28%	Explore
myofibroblast cell	7 studies	35% ± 22%	Explore
retinal cone cell	7 studies	74% ± 24%	Explore
retinal rod cell	7 studies	55% ± 30%	Explore
dendritic cell	7 studies	44% ± 11%	Explore
endothelial cell of artery	7 studies	25% ± 11%	Explore
T cell	7 studies	32% ± 14%	Explore
natural killer cell	6 studies	29% ± 9%	Explore
respiratory goblet cell	6 studies	45% ± 27%	Explore
interneuron	6 studies	83% ± 16%	Explore
retina horizontal cell	6 studies	74% ± 21%	Explore
Mueller cell	6 studies	59% ± 29%	Explore
endothelial cell of vascular tree	6 studies	39% ± 23%	Explore
type II pneumocyte	6 studies	58% ± 18%	Explore
abnormal cell	5 studies	34% ± 23%	Explore
retinal bipolar neuron	5 studies	61% ± 25%	Explore
CD4-positive, alpha-beta T cell	5 studies	27% ± 9%	Explore
cardiac muscle cell	5 studies	67% ± 15%	Explore
lymphocyte	5 studies	34% ± 16%	Explore
monocyte	5 studies	47% ± 10%	Explore
goblet cell	5 studies	36% ± 30%	Explore
regulatory T cell	5 studies	27% ± 9%	Explore
secretory cell	4 studies	28% ± 7%	Explore
squamous epithelial cell	4 studies	42% ± 22%	Explore
glial cell	4 studies	44% ± 9%	Explore
granule cell	4 studies	67% ± 8%	Explore
progenitor cell	4 studies	50% ± 28%	Explore
plasma cell	4 studies	40% ± 9%	Explore
retinal pigment epithelial cell	4 studies	64% ± 27%	Explore
CD8-positive, alpha-beta T cell	4 studies	24% ± 7%	Explore
OFF-bipolar cell	4 studies	74% ± 21%	Explore
ON-bipolar cell	4 studies	72% ± 24%	Explore
memory B cell	4 studies	20% ± 5%	Explore
hepatocyte	4 studies	61% ± 20%	Explore
muscle cell	4 studies	47% ± 27%	Explore
brush cell	4 studies	25% ± 5%	Explore
leukocyte	4 studies	50% ± 20%	Explore
kidney loop of Henle epithelial cell	4 studies	44% ± 27%	Explore
renal principal cell	4 studies	47% ± 27%	Explore
hematopoietic precursor cell	3 studies	37% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	19% ± 3%	Explore
ionocyte	3 studies	34% ± 2%	Explore
cholangiocyte	3 studies	57% ± 21%	Explore
endothelial cell of sinusoid	3 studies	40% ± 12%	Explore
hepatic stellate cell	3 studies	52% ± 23%	Explore
non-classical monocyte	3 studies	25% ± 4%	Explore
glomerular endothelial cell	3 studies	28% ± 4%	Explore
epithelial cell of proximal tubule	3 studies	44% ± 22%	Explore
podocyte	3 studies	62% ± 33%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	69% ± 4%	Explore
interstitial cell of Cajal	3 studies	33% ± 13%	Explore
GABAergic interneuron	3 studies	78% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	31% ± 7%	Explore
endocardial cell	3 studies	48% ± 15%	Explore
mononuclear phagocyte	3 studies	33% ± 5%	Explore
GABAergic amacrine cell	3 studies	88% ± 9%	Explore
glycinergic amacrine cell	3 studies	80% ± 11%	Explore
rod bipolar cell	3 studies	66% ± 22%	Explore
innate lymphoid cell	3 studies	29% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	29% ± 3%	Explore
connective tissue cell	3 studies	48% ± 22%	Explore
ependymal cell	3 studies	78% ± 10%	Explore
hematopoietic stem cell	3 studies	37% ± 24%	Explore
enteroendocrine cell	3 studies	32% ± 9%	Explore
intestinal crypt stem cell	3 studies	18% ± 2%	Explore
adventitial cell	3 studies	31% ± 15%	Explore
alveolar macrophage	3 studies	55% ± 8%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	59% ± 28%	Explore
renal alpha-intercalated cell	3 studies	61% ± 33%	Explore
mural cell	3 studies	59% ± 10%	Explore
mucus secreting cell	3 studies	62% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	18 studies	68% ± 22%	Explore
lung	10 studies	36% ± 18%	Explore
eye	9 studies	58% ± 28%	Explore
heart	5 studies	50% ± 16%	Explore
liver	4 studies	39% ± 25%	Explore
intestine	4 studies	22% ± 6%	Explore
adipose	4 studies	51% ± 29%	Explore
kidney	4 studies	52% ± 23%	Explore
peripheral blood	3 studies	20% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	16157.19	1445 / 1445	100%	38.18	183 / 183
prostate	100%	19952.38	245 / 245	100%	96.81	502 / 502
ovary	100%	13225.69	180 / 180	100%	67.00	429 / 430
breast	100%	18108.00	459 / 459	100%	37.88	1113 / 1118
skin	100%	9711.81	1808 / 1809	100%	39.09	470 / 472
thymus	100%	17427.00	653 / 653	100%	44.31	602 / 605
stomach	100%	10446.15	359 / 359	99%	36.04	284 / 286
intestine	100%	17038.86	966 / 966	99%	32.14	523 / 527
kidney	100%	14646.73	89 / 89	99%	37.15	893 / 901
bladder	100%	17831.52	21 / 21	99%	29.31	499 / 504
lung	100%	12345.57	577 / 578	98%	29.16	1132 / 1155
brain	98%	9459.08	2593 / 2642	99%	37.90	701 / 705
uterus	100%	29484.02	170 / 170	97%	29.28	446 / 459
pancreas	98%	6066.49	320 / 328	99%	28.52	176 / 178
adrenal gland	100%	14300.91	258 / 258	93%	19.77	215 / 230
liver	91%	3855.96	205 / 226	66%	10.38	268 / 406
adipose	100%	16506.51	1204 / 1204	0%	0	0 / 0
blood vessel	100%	18487.50	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	24.87	80 / 80
lymph node	0%	0	0 / 0	100%	28.28	29 / 29
muscle	100%	28838.88	803 / 803	0%	0	0 / 0
spleen	100%	13903.65	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	22.95	45 / 45
ureter	0%	0	0 / 0	100%	15.30	1 / 1
heart	98%	13270.68	841 / 861	0%	0	0 / 0
peripheral blood	82%	6446.94	763 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006338	Biological process	chromatin remodeling
GO_0021942	Biological process	radial glia guided migration of Purkinje cell
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0021930	Biological process	cerebellar granule cell precursor proliferation
GO_0048755	Biological process	branching morphogenesis of a nerve
GO_0021691	Biological process	cerebellar Purkinje cell layer maturation
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0048813	Biological process	dendrite morphogenesis
GO_0000118	Cellular component	histone deacetylase complex
GO_0016604	Cellular component	nuclear body
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0003713	Molecular function	transcription coactivator activity
GO_0003714	Molecular function	transcription corepressor activity
GO_0005515	Molecular function	protein binding
GO_0043565	Molecular function	sequence-specific DNA binding
GO_0046872	Molecular function	metal ion binding
GO_0003682	Molecular function	chromatin binding

IV. Literature review

[source]

Gene name	RERE
Protein name	Arginine-glutamic acid dipeptide repeats Arginine-glutamic acid dipeptide (RE) repeats, isoform CRA_b (Arginine-glutamic acid dipeptide repeats) Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein)
Synonyms	ARP KIAA0458 hCG_2008872 ARG ATN1L
Description	FUNCTION: Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. .
Accessions	K7EIQ4 ENST00000476556.5 [Q9P2R6-2] ENST00000704049.1 ENST00000464972.5 A0A590UJ84 D6RA28 A0A590UK57 ENST00000377464.5 ENST00000656437.1 ENST00000337907.7 [Q9P2R6-1] A0A075B770 ENST00000659924.1 ENST00000505225.1 H0Y975 ENST00000400908.7 [Q9P2R6-1] ENST00000704050.1 ENST00000465125.2 [Q9P2R6-2] A0A994J475 ENST00000464367.1 H7BYW9 ENST00000488215.5 ENST00000468247.1 A0A994J792 B1AKN3 ENST00000514428.1 Q9P2R6 ENST00000400907.6 K7EIE3 K7EJQ1

RERE report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review