COMMD7 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	24 studies	25% ± 8%	Explore
endothelial cell	14 studies	26% ± 11%	Explore
CD8-positive, alpha-beta T cell	12 studies	24% ± 7%	Explore
non-classical monocyte	10 studies	28% ± 15%	Explore
CD4-positive, alpha-beta T cell	10 studies	22% ± 6%	Explore
mature NK T cell	10 studies	23% ± 6%	Explore
regulatory T cell	10 studies	23% ± 6%	Explore
gamma-delta T cell	9 studies	26% ± 8%	Explore
classical monocyte	8 studies	24% ± 11%	Explore
conventional dendritic cell	8 studies	24% ± 13%	Explore
T cell	7 studies	21% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	29% ± 7%	Explore
B cell	6 studies	21% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	22% ± 5%	Explore
smooth muscle cell	6 studies	19% ± 4%	Explore
epithelial cell	6 studies	37% ± 14%	Explore
monocyte	6 studies	19% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	30% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	19% ± 5%	Explore
mucosal invariant T cell	5 studies	19% ± 3%	Explore
pericyte	5 studies	23% ± 6%	Explore
platelet	5 studies	20% ± 3%	Explore
ciliated cell	5 studies	32% ± 9%	Explore
macrophage	5 studies	22% ± 7%	Explore
neuron	5 studies	27% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	26% ± 7%	Explore
exhausted T cell	4 studies	28% ± 7%	Explore
connective tissue cell	4 studies	19% ± 3%	Explore
hematopoietic stem cell	4 studies	28% ± 8%	Explore
megakaryocyte	4 studies	45% ± 19%	Explore
endothelial cell of vascular tree	4 studies	19% ± 1%	Explore
fibroblast	4 studies	22% ± 5%	Explore
innate lymphoid cell	4 studies	21% ± 5%	Explore
glutamatergic neuron	4 studies	35% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	22% ± 2%	Explore
plasmacytoid dendritic cell	4 studies	23% ± 7%	Explore
pancreatic A cell	3 studies	21% ± 1%	Explore
hematopoietic precursor cell	3 studies	46% ± 18%	Explore
endothelial cell of artery	3 studies	18% ± 3%	Explore
placental villous trophoblast	3 studies	36% ± 15%	Explore
myeloid cell	3 studies	27% ± 7%	Explore
intraepithelial lymphocyte	3 studies	24% ± 7%	Explore
GABAergic neuron	3 studies	33% ± 11%	Explore
dendritic cell	3 studies	47% ± 14%	Explore
granulocyte monocyte progenitor cell	3 studies	26% ± 8%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	35% ± 5%	Explore
goblet cell	3 studies	21% ± 5%	Explore
interneuron	3 studies	28% ± 16%	Explore
T-helper 17 cell	3 studies	20% ± 1%	Explore
basal cell	3 studies	38% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	24% ± 9%	Explore
lung	5 studies	27% ± 9%	Explore
brain	5 studies	24% ± 11%	Explore
pancreas	3 studies	21% ± 4%	Explore
placenta	3 studies	26% ± 8%	Explore
bone marrow	3 studies	18% ± 1%	Explore
liver	3 studies	22% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2639.63	258 / 258	100%	36.94	230 / 230
kidney	100%	3418.74	89 / 89	100%	63.11	901 / 901
lung	100%	2568.75	578 / 578	100%	53.99	1155 / 1155
ovary	100%	2138.24	180 / 180	100%	63.66	430 / 430
pancreas	100%	1485.99	328 / 328	100%	60.26	178 / 178
thymus	100%	4010.96	653 / 653	100%	76.64	605 / 605
skin	100%	2508.86	1808 / 1809	100%	58.21	472 / 472
brain	100%	2643.59	2640 / 2642	100%	58.23	705 / 705
prostate	100%	3410.27	245 / 245	100%	64.44	501 / 502
stomach	100%	2082.90	359 / 359	100%	58.01	285 / 286
bladder	100%	3100.71	21 / 21	100%	77.19	502 / 504
breast	100%	2934.20	459 / 459	100%	80.16	1113 / 1118
intestine	100%	2710.92	966 / 966	99%	61.58	524 / 527
uterus	100%	2642.76	170 / 170	99%	56.61	456 / 459
liver	100%	1645.43	226 / 226	99%	41.16	403 / 406
esophagus	100%	2504.16	1444 / 1445	98%	37.08	180 / 183
adipose	100%	2571.65	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	46.51	80 / 80
lymph node	0%	0	0 / 0	100%	68.41	29 / 29
spleen	100%	3073.71	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	37.25	45 / 45
ureter	0%	0	0 / 0	100%	75.64	1 / 1
blood vessel	100%	2908.74	1334 / 1335	0%	0	0 / 0
heart	100%	2338.15	860 / 861	0%	0	0 / 0
muscle	100%	2173.18	802 / 803	0%	0	0 / 0
peripheral blood	98%	1504.11	911 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0033209	Biological process	tumor necrosis factor-mediated signaling pathway
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0032088	Biological process	negative regulation of NF-kappaB transcription factor activity
GO_0031410	Cellular component	cytoplasmic vesicle
GO_0005515	Molecular function	protein binding
GO_0051059	Molecular function	NF-kappaB binding

IV. Literature review

[source]

Gene name	COMMD7
Protein name	COMM domain containing 7 COMM domain-containing protein 7
Synonyms	C20orf92
Description	FUNCTION: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes . Associates with the NF-kappa-B complex and suppresses its transcriptional activity . .
Accessions	V9GY66 ENST00000446419.6 [Q86VX2-2] ENST00000610160.1 ENST00000474815.2 V9GYC5 Q86VX2 ENST00000278980.11 [Q86VX2-1]

COMMD7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review