Name | Number of supported studies | Average coverage | |
---|---|---|---|
regulatory T cell | 21 studies | 41% ± 18% | |
CD4-positive, alpha-beta T cell | 8 studies | 36% ± 12% | |
endothelial cell | 7 studies | 25% ± 7% | |
mast cell | 5 studies | 21% ± 3% | |
innate lymphoid cell | 5 studies | 35% ± 9% | |
CD4-positive, alpha-beta memory T cell | 5 studies | 33% ± 17% | |
CD8-positive, alpha-beta T cell | 5 studies | 22% ± 5% | |
T cell | 4 studies | 20% ± 4% | |
capillary endothelial cell | 4 studies | 18% ± 1% | |
T follicular helper cell | 4 studies | 35% ± 11% | |
effector memory CD4-positive, alpha-beta T cell | 4 studies | 33% ± 18% | |
CD4-positive helper T cell | 3 studies | 17% ± 2% | |
T-helper 17 cell | 3 studies | 40% ± 14% | |
endothelial cell of lymphatic vessel | 3 studies | 24% ± 6% | |
natural killer cell | 3 studies | 31% ± 5% | |
CD4-positive, alpha-beta cytotoxic T cell | 3 studies | 48% ± 8% |
Insufficient scRNA-seq data for expression of TNFRSF4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 451.47 | 576 / 578 | 95% | 10.11 | 1096 / 1155 |
thymus | 100% | 299.73 | 650 / 653 | 95% | 10.18 | 573 / 605 |
breast | 100% | 376.50 | 458 / 459 | 91% | 7.85 | 1020 / 1118 |
stomach | 86% | 107.01 | 307 / 359 | 94% | 8.73 | 269 / 286 |
intestine | 86% | 178.69 | 827 / 966 | 91% | 7.74 | 480 / 527 |
bladder | 90% | 102.10 | 19 / 21 | 86% | 8.13 | 433 / 504 |
uterus | 86% | 76.41 | 146 / 170 | 89% | 8.20 | 408 / 459 |
kidney | 87% | 132.93 | 77 / 89 | 79% | 11.80 | 711 / 901 |
prostate | 98% | 240.27 | 240 / 245 | 62% | 2.94 | 310 / 502 |
ovary | 55% | 43.93 | 99 / 180 | 96% | 7.50 | 413 / 430 |
esophagus | 63% | 57.19 | 909 / 1445 | 84% | 5.39 | 154 / 183 |
skin | 46% | 38.40 | 831 / 1809 | 88% | 11.19 | 416 / 472 |
pancreas | 31% | 29.04 | 102 / 328 | 93% | 8.74 | 165 / 178 |
adrenal gland | 26% | 16.72 | 68 / 258 | 83% | 8.07 | 190 / 230 |
liver | 18% | 11.54 | 41 / 226 | 85% | 6.25 | 347 / 406 |
lymph node | 0% | 0 | 0 / 0 | 100% | 66.52 | 29 / 29 |
spleen | 100% | 803.83 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.48 | 1 / 1 |
adipose | 100% | 441.53 | 1203 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 12.89 | 44 / 45 |
peripheral blood | 90% | 355.12 | 833 / 929 | 0% | 0 | 0 / 0 |
heart | 89% | 237.41 | 763 / 861 | 0% | 0 | 0 / 0 |
muscle | 74% | 73.02 | 597 / 803 | 0% | 0 | 0 / 0 |
brain | 29% | 20.27 | 758 / 2642 | 37% | 1.86 | 259 / 705 |
blood vessel | 62% | 68.79 | 826 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 36% | 1.92 | 29 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006955 | Biological process | immune response |
GO_0046718 | Biological process | symbiont entry into host cell |
GO_0006954 | Biological process | inflammatory response |
GO_0002639 | Biological process | positive regulation of immunoglobulin production |
GO_0033209 | Biological process | tumor necrosis factor-mediated signaling pathway |
GO_0030890 | Biological process | positive regulation of B cell proliferation |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0042098 | Biological process | T cell proliferation |
GO_0043433 | Biological process | negative regulation of DNA-binding transcription factor activity |
GO_0009986 | Cellular component | cell surface |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005031 | Molecular function | tumor necrosis factor receptor activity |
GO_0005515 | Molecular function | protein binding |
GO_0001618 | Molecular function | virus receptor activity |
Gene name | TNFRSF4 |
Protein name | Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134) TNF receptor superfamily member 4 |
Synonyms | TXGP1L |
Description | FUNCTION: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. .; FUNCTION: (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B. . |
Accessions | A0A8V8TPH7 A0A8V8TPP1 ENST00000699969.1 ENST00000699977.1 ENST00000379236.4 A0A8V8TQV3 A0A8V8TQH9 ENST00000699974.1 A0A8V8TPN6 ENST00000699970.1 ENST00000699973.1 ENST00000699975.1 A0A8V8TP56 ENST00000699976.1 A0A8V8TP52 A0A8V8TQH5 A0A8V8TPH3 P43489 A0A8V8TQV7 ENST00000699979.1 ENST00000699978.1 ENST00000699971.1 |