FOXN3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	32 studies	39% ± 22%	Explore
natural killer cell	30 studies	30% ± 15%	Explore
endothelial cell	30 studies	47% ± 17%	Explore
fibroblast	27 studies	34% ± 16%	Explore
B cell	24 studies	28% ± 14%	Explore
T cell	18 studies	33% ± 18%	Explore
CD4-positive, alpha-beta T cell	18 studies	31% ± 15%	Explore
CD8-positive, alpha-beta T cell	18 studies	30% ± 15%	Explore
astrocyte	17 studies	50% ± 22%	Explore
microglial cell	17 studies	70% ± 20%	Explore
regulatory T cell	17 studies	29% ± 16%	Explore
classical monocyte	16 studies	25% ± 12%	Explore
smooth muscle cell	16 studies	32% ± 12%	Explore
conventional dendritic cell	15 studies	27% ± 15%	Explore
pericyte	15 studies	28% ± 13%	Explore
mature NK T cell	14 studies	27% ± 14%	Explore
dendritic cell	13 studies	48% ± 24%	Explore
oligodendrocyte precursor cell	13 studies	52% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	32% ± 16%	Explore
gamma-delta T cell	13 studies	25% ± 8%	Explore
mast cell	13 studies	37% ± 15%	Explore
basal cell	12 studies	39% ± 19%	Explore
naive B cell	12 studies	20% ± 4%	Explore
glutamatergic neuron	12 studies	48% ± 23%	Explore
oligodendrocyte	12 studies	35% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	35% ± 14%	Explore
myeloid cell	12 studies	49% ± 23%	Explore
capillary endothelial cell	11 studies	29% ± 13%	Explore
adipocyte	11 studies	57% ± 19%	Explore
club cell	10 studies	37% ± 16%	Explore
GABAergic neuron	10 studies	55% ± 23%	Explore
mucosal invariant T cell	10 studies	29% ± 16%	Explore
monocyte	10 studies	44% ± 22%	Explore
endothelial cell of artery	10 studies	31% ± 15%	Explore
endothelial cell of lymphatic vessel	9 studies	33% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	30% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	25% ± 9%	Explore
leukocyte	9 studies	38% ± 26%	Explore
epithelial cell	9 studies	49% ± 22%	Explore
ciliated cell	9 studies	38% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	28% ± 8%	Explore
non-classical monocyte	8 studies	31% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	37% ± 18%	Explore
neuron	8 studies	44% ± 25%	Explore
myofibroblast cell	8 studies	35% ± 17%	Explore
memory B cell	8 studies	19% ± 5%	Explore
amacrine cell	8 studies	50% ± 21%	Explore
connective tissue cell	8 studies	28% ± 11%	Explore
mononuclear phagocyte	7 studies	35% ± 17%	Explore
retinal ganglion cell	7 studies	61% ± 20%	Explore
innate lymphoid cell	7 studies	40% ± 19%	Explore
respiratory goblet cell	6 studies	43% ± 26%	Explore
retina horizontal cell	6 studies	50% ± 15%	Explore
endothelial cell of vascular tree	6 studies	34% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	23% ± 5%	Explore
type I pneumocyte	6 studies	37% ± 11%	Explore
type II pneumocyte	6 studies	39% ± 13%	Explore
hematopoietic precursor cell	5 studies	34% ± 19%	Explore
hepatocyte	5 studies	64% ± 24%	Explore
retinal bipolar neuron	5 studies	58% ± 25%	Explore
interneuron	5 studies	68% ± 21%	Explore
plasma cell	5 studies	49% ± 18%	Explore
cardiac muscle cell	5 studies	53% ± 12%	Explore
mesothelial cell	5 studies	33% ± 9%	Explore
vein endothelial cell	5 studies	30% ± 7%	Explore
lymphocyte	5 studies	46% ± 16%	Explore
abnormal cell	4 studies	33% ± 24%	Explore
granule cell	4 studies	60% ± 16%	Explore
pro-B cell	4 studies	28% ± 5%	Explore
retinal pigment epithelial cell	4 studies	47% ± 18%	Explore
Mueller cell	4 studies	47% ± 7%	Explore
OFF-bipolar cell	4 studies	62% ± 19%	Explore
ON-bipolar cell	4 studies	66% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	25% ± 13%	Explore
muscle cell	4 studies	35% ± 20%	Explore
hematopoietic stem cell	4 studies	36% ± 17%	Explore
goblet cell	4 studies	40% ± 34%	Explore
alveolar macrophage	4 studies	51% ± 22%	Explore
secretory cell	3 studies	26% ± 1%	Explore
hepatic stellate cell	3 studies	46% ± 20%	Explore
exhausted T cell	3 studies	24% ± 10%	Explore
glial cell	3 studies	36% ± 9%	Explore
progenitor cell	3 studies	50% ± 12%	Explore
endocardial cell	3 studies	36% ± 14%	Explore
tissue-resident macrophage	3 studies	39% ± 17%	Explore
GABAergic amacrine cell	3 studies	66% ± 2%	Explore
glycinergic amacrine cell	3 studies	57% ± 8%	Explore
rod bipolar cell	3 studies	67% ± 16%	Explore
enteroendocrine cell	3 studies	30% ± 8%	Explore
intestinal crypt stem cell	3 studies	19% ± 1%	Explore
adventitial cell	3 studies	33% ± 17%	Explore
chondrocyte	3 studies	37% ± 13%	Explore
T follicular helper cell	3 studies	21% ± 3%	Explore
group 3 innate lymphoid cell	3 studies	39% ± 14%	Explore
Schwann cell	3 studies	26% ± 3%	Explore
transit amplifying cell	3 studies	38% ± 33%	Explore
keratinocyte	3 studies	33% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	41% ± 23%	Explore
mucus secreting cell	3 studies	44% ± 18%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	18 studies	46% ± 19%	Explore
lung	13 studies	31% ± 14%	Explore
peripheral blood	12 studies	27% ± 12%	Explore
eye	7 studies	35% ± 16%	Explore
liver	6 studies	36% ± 20%	Explore
heart	5 studies	49% ± 15%	Explore
kidney	5 studies	21% ± 5%	Explore
bone marrow	4 studies	30% ± 13%	Explore
intestine	4 studies	23% ± 7%	Explore
adipose	4 studies	44% ± 22%	Explore
lymph node	3 studies	21% ± 1%	Explore
skin	3 studies	26% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5954.77	1444 / 1445	100%	25.23	183 / 183
stomach	100%	4147.66	359 / 359	99%	18.03	284 / 286
prostate	100%	4239.34	244 / 245	100%	19.09	500 / 502
lung	99%	4562.41	573 / 578	100%	19.12	1151 / 1155
uterus	100%	6106.30	170 / 170	98%	15.51	452 / 459
intestine	100%	6637.98	966 / 966	98%	13.46	518 / 527
breast	100%	6704.15	459 / 459	98%	14.90	1093 / 1118
bladder	100%	7155.86	21 / 21	97%	12.78	491 / 504
ovary	100%	8106.98	180 / 180	97%	10.37	418 / 430
skin	100%	8780.29	1808 / 1809	96%	14.04	451 / 472
adrenal gland	100%	4485.47	258 / 258	95%	11.22	218 / 230
thymus	97%	2747.09	634 / 653	98%	11.97	590 / 605
liver	90%	1877.03	204 / 226	97%	12.13	392 / 406
brain	86%	3011.28	2285 / 2642	100%	20.13	702 / 705
pancreas	80%	1565.17	264 / 328	98%	14.70	175 / 178
kidney	75%	1579.45	67 / 89	96%	17.95	861 / 901
adipose	100%	8407.20	1204 / 1204	0%	0	0 / 0
blood vessel	100%	10384.91	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	18.10	29 / 29
muscle	100%	8848.77	803 / 803	0%	0	0 / 0
spleen	100%	2586.66	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	17.05	45 / 45
ureter	0%	0	0 / 0	100%	6.29	1 / 1
eye	0%	0	0 / 0	96%	14.35	77 / 80
heart	94%	3895.85	813 / 861	0%	0	0 / 0
peripheral blood	89%	3268.33	829 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007095	Biological process	mitotic G2 DNA damage checkpoint signaling
GO_0097094	Biological process	craniofacial suture morphogenesis
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0006355	Biological process	regulation of DNA-templated transcription
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000987	Molecular function	cis-regulatory region sequence-specific DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	FOXN3
Protein name	Forkhead box protein N3 (Checkpoint suppressor 1) Forkhead box N3 Forkhead box protein N3
Synonyms	C14orf116 CHES1
Description	FUNCTION: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints). . FUNCTION: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints). .
Accessions	ENST00000553353.5 ENST00000615335.4 [O00409-2] ENST00000261302.9 [O00409-1] ENST00000557718.5 H0YJ94 G3V4N5 H0YJ22 G3V5C7 H0YJG3 ENST00000557258.6 [O00409-2] ENST00000554005.1 ENST00000555855.5 ENST00000345097.8 [O00409-1] ENST00000553840.5 ENST00000555353.5 [O00409-2] G3V3A7 O00409 ENST00000557572.1 ENST00000553904.1 H0YJY0 H0YJ54 ENST00000556916.5 ENST00000555034.5 H0YJ43

FOXN3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review