Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 13 studies | 32% ± 16% | |
astrocyte | 12 studies | 39% ± 18% | |
oligodendrocyte precursor cell | 5 studies | 34% ± 9% | |
fibroblast | 5 studies | 23% ± 6% | |
endothelial cell of lymphatic vessel | 5 studies | 28% ± 7% | |
interneuron | 4 studies | 40% ± 6% | |
pericyte | 4 studies | 28% ± 17% | |
adipocyte | 4 studies | 24% ± 2% | |
neuron | 3 studies | 36% ± 11% | |
progenitor cell | 3 studies | 35% ± 12% | |
vein endothelial cell | 3 studies | 33% ± 17% | |
amacrine cell | 3 studies | 31% ± 7% | |
glycinergic amacrine cell | 3 studies | 38% ± 10% | |
endothelial cell of vascular tree | 3 studies | 26% ± 11% | |
smooth muscle cell | 3 studies | 21% ± 2% | |
GABAergic neuron | 3 studies | 49% ± 6% | |
glutamatergic neuron | 3 studies | 43% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 37% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1358.02 | 2638 / 2642 | 97% | 18.42 | 685 / 705 |
prostate | 99% | 1453.31 | 243 / 245 | 74% | 3.45 | 369 / 502 |
ovary | 99% | 1207.19 | 179 / 180 | 73% | 8.97 | 313 / 430 |
adrenal gland | 84% | 378.38 | 218 / 258 | 84% | 11.15 | 194 / 230 |
breast | 100% | 1560.40 | 458 / 459 | 68% | 4.00 | 762 / 1118 |
thymus | 100% | 1020.64 | 651 / 653 | 64% | 3.11 | 386 / 605 |
pancreas | 70% | 222.55 | 231 / 328 | 81% | 4.39 | 145 / 178 |
intestine | 98% | 838.83 | 946 / 966 | 44% | 2.11 | 231 / 527 |
bladder | 100% | 852.29 | 21 / 21 | 38% | 1.71 | 189 / 504 |
esophagus | 87% | 791.29 | 1264 / 1445 | 44% | 2.31 | 80 / 183 |
uterus | 100% | 1520.38 | 170 / 170 | 28% | 3.64 | 128 / 459 |
kidney | 80% | 314.99 | 71 / 89 | 44% | 1.91 | 393 / 901 |
lung | 97% | 665.75 | 563 / 578 | 26% | 1.35 | 298 / 1155 |
stomach | 59% | 351.38 | 212 / 359 | 55% | 3.24 | 156 / 286 |
muscle | 100% | 1810.58 | 803 / 803 | 0% | 0 | 0 / 0 |
adipose | 100% | 1670.45 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 1082.72 | 1327 / 1335 | 0% | 0 | 0 / 0 |
heart | 97% | 898.37 | 835 / 861 | 0% | 0 | 0 / 0 |
skin | 65% | 324.68 | 1183 / 1809 | 20% | 1.04 | 96 / 472 |
spleen | 59% | 186.31 | 141 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 51% | 1.76 | 41 / 80 |
tonsil | 0% | 0 | 0 / 0 | 18% | 0.87 | 8 / 45 |
liver | 1% | 3.64 | 3 / 226 | 7% | 0.20 | 28 / 406 |
peripheral blood | 0% | 0.56 | 2 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0061512 | Biological process | protein localization to cilium |
GO_0007399 | Biological process | nervous system development |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0030154 | Biological process | cell differentiation |
GO_0007219 | Biological process | Notch signaling pathway |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0030513 | Biological process | positive regulation of BMP signaling pathway |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0120163 | Biological process | negative regulation of cold-induced thermogenesis |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0005515 | Molecular function | protein binding |
GO_0043565 | Molecular function | sequence-specific DNA binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | ZNF423 |
Protein name | Zinc finger protein 423 (Olf1/EBF-associated zinc finger protein) (hOAZ) (Smad- and Olf-interacting zinc finger protein) Zinc finger protein 423 |
Synonyms | KIAA0760 NPHP14 OAZ |
Description | FUNCTION: Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation. . |
Accessions | ENST00000568094.2 ENST00000562520.1 [Q2M1K9-2] Q2M1K9 F5H7S1 ENST00000567169.5 ENST00000535559.5 ENST00000563137.7 A0A7P0Q1F0 A0A087WV99 ENST00000561648.5 [Q2M1K9-1] ENST00000562871.5 [Q2M1K9-2] |