Insufficient scRNA-seq data for expression of SCX at single-cell level.
Insufficient scRNA-seq data for expression of SCX at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 1684.98 | 653 / 653 | 99% | 115.76 | 599 / 605 |
ovary | 76% | 90.21 | 136 / 180 | 99% | 94.77 | 424 / 430 |
stomach | 96% | 199.79 | 346 / 359 | 64% | 9.83 | 182 / 286 |
intestine | 98% | 270.01 | 945 / 966 | 59% | 7.36 | 311 / 527 |
esophagus | 80% | 149.69 | 1156 / 1445 | 69% | 8.68 | 127 / 183 |
adrenal gland | 87% | 125.30 | 224 / 258 | 61% | 10.61 | 141 / 230 |
uterus | 80% | 168.59 | 136 / 170 | 65% | 51.06 | 300 / 459 |
bladder | 81% | 103.14 | 17 / 21 | 60% | 7.65 | 302 / 504 |
lung | 94% | 145.24 | 541 / 578 | 38% | 5.49 | 435 / 1155 |
brain | 90% | 299.90 | 2383 / 2642 | 37% | 7.01 | 264 / 705 |
prostate | 99% | 195.84 | 242 / 245 | 25% | 2.52 | 126 / 502 |
kidney | 99% | 221.09 | 88 / 89 | 18% | 2.22 | 158 / 901 |
pancreas | 63% | 71.58 | 208 / 328 | 48% | 7.13 | 86 / 178 |
ureter | 0% | 0 | 0 / 0 | 100% | 14.07 | 1 / 1 |
spleen | 99% | 187.79 | 239 / 241 | 0% | 0 | 0 / 0 |
heart | 94% | 199.25 | 811 / 861 | 0% | 0 | 0 / 0 |
muscle | 92% | 212.62 | 739 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 89% | 377.22 | 1185 / 1335 | 0% | 0 | 0 / 0 |
skin | 67% | 87.74 | 1203 / 1809 | 8% | 5.54 | 36 / 472 |
breast | 44% | 44.69 | 204 / 459 | 23% | 2.57 | 255 / 1118 |
liver | 29% | 24.03 | 65 / 226 | 16% | 1.84 | 66 / 406 |
lymph node | 0% | 0 | 0 / 0 | 41% | 10.52 | 12 / 29 |
tonsil | 0% | 0 | 0 / 0 | 29% | 2.56 | 13 / 45 |
adipose | 29% | 29.93 | 345 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 15% | 1.91 | 12 / 80 |
peripheral blood | 6% | 4.39 | 55 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0035992 | Biological process | tendon formation |
GO_0071560 | Biological process | cellular response to transforming growth factor beta stimulus |
GO_0061056 | Biological process | sclerotome development |
GO_2000543 | Biological process | positive regulation of gastrulation |
GO_0071260 | Biological process | cellular response to mechanical stimulus |
GO_0035989 | Biological process | tendon development |
GO_0032502 | Biological process | developmental process |
GO_0035990 | Biological process | tendon cell differentiation |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0003188 | Biological process | heart valve formation |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0002062 | Biological process | chondrocyte differentiation |
GO_0003179 | Biological process | heart valve morphogenesis |
GO_0001958 | Biological process | endochondral ossification |
GO_0060008 | Biological process | Sertoli cell differentiation |
GO_0030509 | Biological process | BMP signaling pathway |
GO_0006351 | Biological process | DNA-templated transcription |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0001707 | Biological process | mesoderm formation |
GO_0032967 | Biological process | positive regulation of collagen biosynthetic process |
GO_0030154 | Biological process | cell differentiation |
GO_0035993 | Biological process | deltoid tuberosity development |
GO_0048706 | Biological process | embryonic skeletal system development |
GO_0061035 | Biological process | regulation of cartilage development |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0030199 | Biological process | collagen fibril organization |
GO_0001894 | Biological process | tissue homeostasis |
GO_0035914 | Biological process | skeletal muscle cell differentiation |
GO_0060325 | Biological process | face morphogenesis |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0061036 | Biological process | positive regulation of cartilage development |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005667 | Cellular component | transcription regulator complex |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0043425 | Molecular function | bHLH transcription factor binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0043565 | Molecular function | sequence-specific DNA binding |
GO_0070888 | Molecular function | E-box binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SCX |
Protein name | Basic helix-loop-helix transcription factor scleraxis (Class A basic helix-loop-helix protein 41) (bHLHa41) (Class A basic helix-loop-helix protein 48) (bHLHa48) |
Synonyms | BHLHA48 SCXA SCXB BHLHA41 |
Description | FUNCTION: Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages. . |
Accessions | ENST00000567180.3 Q7RTU7 |