RUNX1T1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006351Biological processDNA-templated transcription
GO_0045599Biological processnegative regulation of fat cell differentiation
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0016363Cellular componentnuclear matrix
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0140297Molecular functionDNA-binding transcription factor binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameRUNX1T1
Protein nameCBFA2T1 isoform r1t1-7a51
CBFA2T1 isoform r1t1-8a59
CBFA2T1 isoform r1t1-7a47
CBFA2T1 isoform r1t1-7a49 (Putative transcription factor)
CBFA2T1 isoform r1t1-7a52
CBFA2T1 isoform r1t1-7a48
CBFA2T1 isoform r1t1-8a57
CBFA2T1 isoform r1t1-11a63
Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2)
RUNX1 partner transcriptional co-repressor 1
CBFA2T1 isoform r1t1-7a50
CBFA2T1 isoform r1t1-11a65
CBFA2T1 isoform r1t1-7d56 (CBFA2T1 isoform r1t1-8a60)
CBFA2T1 isoform r1t1-11a62 (CBFA2T1 isoform r1t1-11a64)
CBFA2T1 isoform r1t1-7d53 (CBFA2T1 isoform r1t1-7d54) (CBFA2T1 isoform r1t1-7d55) (CBFA2T1 isoform r1t1-8a58)
CBFA2T1 isoform r1t1-11a61
RUNX1 partner transcriptional co-repressor 1 (Runt-related transcription factor 1 translocated to, 1 (Cyclin D-related), isoform CRA_c)
SynonymsCDR
MTG8
AML1T1
ZMYND2
hCG_20715
CBFA2T1
ETO
DescriptionFUNCTION: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes . Can repress the expression of MMP7 in a ZBTB33-dependent manner . Can repress transactivation mediated by TCF12 . Acts as a negative regulator of adipogenesis (By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal . .

AccessionsENST00000396218.5 [Q06455-2]
W8FKX0
E5RJ32
ENST00000517919.6 [Q06455-1]
ENST00000436581.7
ENST00000518844.5 [Q06455-2]
ENST00000520556.5
ENST00000519847.6
E5RHJ8
ENST00000521897.5
ENST00000517919.6
W8FSQ8
Q71VC3
W8FSP9
ENST00000519847.6 [Q06455-1]
E7EQW7
E5RFQ3
W8FP49
W8FP62
E7EQW3
ENST00000422361.6 [Q06455-4]
ENST00000519422.5
E5RH72
E5RJB3
ENST00000522163.6
W8FW28
ENST00000518823.5
E5RH30
ENST00000360348.6 [Q06455-4]
E7EQI9
ENST00000521553.5
ENST00000520974.5
W8FK92
ENST00000520724.5 [Q06455-3]
ENST00000524215.5
ENST00000518361.1
W8FW32
ENST00000518954.6
H0YC25
ENST00000523629.6 [Q06455-1]
E7EWJ9
E7EX23
E5RK76
H0YBA6
E7ESA9
ENST00000520428.5
W8FSQ5
E7ERJ9
ENST00000518992.5
ENST00000518832.2
ENST00000517792.5
ENST00000521319.5
E5RI38
E7EQJ1
ENST00000521733.5
W8FK78
ENST00000519061.5
ENST00000521375.5
E7EQ59
Q06455
W8FSQ2
ENST00000522467.5
W8FW37
ENST00000519577.5
E7ETA8
H0YC43
E5RJE7
ENST00000521751.5
ENST00000520978.5
ENST00000518317.6
ENST00000523168.5
ENST00000521054.5
W8FP57
ENST00000520583.5
ENST00000518317.6 [Q06455-2]
A0A0A0MSU1
ENST00000518954.6 [Q06455-1]
E5RG85
A0A1B0GX92
E7ESL1