Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 32 studies | 29% ± 11% | |
endothelial cell | 26 studies | 37% ± 17% | |
pericyte | 20 studies | 30% ± 14% | |
oligodendrocyte precursor cell | 15 studies | 40% ± 19% | |
smooth muscle cell | 15 studies | 29% ± 14% | |
astrocyte | 12 studies | 33% ± 14% | |
glutamatergic neuron | 12 studies | 66% ± 19% | |
GABAergic neuron | 11 studies | 56% ± 22% | |
connective tissue cell | 8 studies | 29% ± 8% | |
adipocyte | 8 studies | 27% ± 6% | |
amacrine cell | 7 studies | 47% ± 22% | |
endothelial cell of artery | 7 studies | 32% ± 16% | |
endothelial cell of lymphatic vessel | 7 studies | 40% ± 10% | |
myofibroblast cell | 6 studies | 23% ± 11% | |
interneuron | 6 studies | 53% ± 18% | |
capillary endothelial cell | 5 studies | 23% ± 11% | |
neuron | 5 studies | 50% ± 20% | |
retinal bipolar neuron | 5 studies | 53% ± 19% | |
retina horizontal cell | 5 studies | 35% ± 19% | |
cardiac muscle cell | 5 studies | 41% ± 6% | |
mesothelial cell | 4 studies | 35% ± 11% | |
granule cell | 4 studies | 59% ± 23% | |
retinal ganglion cell | 4 studies | 33% ± 19% | |
vein endothelial cell | 4 studies | 37% ± 16% | |
endothelial cell of vascular tree | 4 studies | 34% ± 15% | |
GABAergic interneuron | 3 studies | 57% ± 5% | |
progenitor cell | 3 studies | 50% ± 7% | |
endocardial cell | 3 studies | 30% ± 15% | |
GABAergic amacrine cell | 3 studies | 56% ± 11% | |
OFF-bipolar cell | 3 studies | 46% ± 12% | |
ON-bipolar cell | 3 studies | 57% ± 16% | |
glycinergic amacrine cell | 3 studies | 42% ± 25% | |
rod bipolar cell | 3 studies | 66% ± 13% | |
adventitial cell | 3 studies | 28% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 96% | 2174.14 | 2529 / 2642 | 87% | 3.27 | 612 / 705 |
breast | 100% | 1828.76 | 459 / 459 | 60% | 1.54 | 676 / 1118 |
adrenal gland | 74% | 375.48 | 190 / 258 | 76% | 3.44 | 175 / 230 |
thymus | 99% | 1336.41 | 649 / 653 | 48% | 1.02 | 292 / 605 |
lung | 99% | 1226.84 | 573 / 578 | 40% | 1.09 | 465 / 1155 |
prostate | 96% | 804.55 | 235 / 245 | 42% | 0.71 | 209 / 502 |
ovary | 98% | 930.87 | 176 / 180 | 27% | 0.79 | 114 / 430 |
uterus | 99% | 2224.79 | 169 / 170 | 24% | 1.15 | 110 / 459 |
intestine | 94% | 1677.71 | 911 / 966 | 26% | 0.60 | 137 / 527 |
bladder | 100% | 1311.95 | 21 / 21 | 19% | 0.49 | 96 / 504 |
stomach | 70% | 797.86 | 253 / 359 | 45% | 1.50 | 128 / 286 |
esophagus | 82% | 1267.54 | 1180 / 1445 | 33% | 0.79 | 61 / 183 |
skin | 93% | 1225.11 | 1689 / 1809 | 13% | 0.34 | 62 / 472 |
blood vessel | 100% | 1293.24 | 1332 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 2043.88 | 1201 / 1204 | 0% | 0 | 0 / 0 |
heart | 96% | 1010.19 | 830 / 861 | 0% | 0 | 0 / 0 |
kidney | 57% | 321.99 | 51 / 89 | 39% | 0.99 | 348 / 901 |
pancreas | 14% | 63.45 | 46 / 328 | 81% | 2.55 | 145 / 178 |
spleen | 78% | 385.15 | 187 / 241 | 0% | 0 | 0 / 0 |
muscle | 76% | 384.07 | 607 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 19% | 0.32 | 15 / 80 |
liver | 4% | 15.81 | 9 / 226 | 5% | 0.09 | 20 / 406 |
tonsil | 0% | 0 | 0 / 0 | 9% | 0.14 | 4 / 45 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
peripheral blood | 0% | 0.36 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006351 | Biological process | DNA-templated transcription |
GO_0045599 | Biological process | negative regulation of fat cell differentiation |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0016363 | Cellular component | nuclear matrix |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0140297 | Molecular function | DNA-binding transcription factor binding |
GO_0003714 | Molecular function | transcription corepressor activity |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | RUNX1T1 |
Protein name | CBFA2T1 isoform r1t1-7a51 CBFA2T1 isoform r1t1-8a59 CBFA2T1 isoform r1t1-7a47 CBFA2T1 isoform r1t1-7a49 (Putative transcription factor) CBFA2T1 isoform r1t1-7a52 CBFA2T1 isoform r1t1-7a48 CBFA2T1 isoform r1t1-8a57 CBFA2T1 isoform r1t1-11a63 Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2) RUNX1 partner transcriptional co-repressor 1 CBFA2T1 isoform r1t1-7a50 CBFA2T1 isoform r1t1-11a65 CBFA2T1 isoform r1t1-7d56 (CBFA2T1 isoform r1t1-8a60) CBFA2T1 isoform r1t1-11a62 (CBFA2T1 isoform r1t1-11a64) CBFA2T1 isoform r1t1-7d53 (CBFA2T1 isoform r1t1-7d54) (CBFA2T1 isoform r1t1-7d55) (CBFA2T1 isoform r1t1-8a58) CBFA2T1 isoform r1t1-11a61 RUNX1 partner transcriptional co-repressor 1 (Runt-related transcription factor 1 translocated to, 1 (Cyclin D-related), isoform CRA_c) |
Synonyms | CDR MTG8 AML1T1 ZMYND2 hCG_20715 CBFA2T1 ETO |
Description | FUNCTION: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes . Can repress the expression of MMP7 in a ZBTB33-dependent manner . Can repress transactivation mediated by TCF12 . Acts as a negative regulator of adipogenesis (By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal . . |
Accessions | ENST00000396218.5 [Q06455-2] W8FKX0 E5RJ32 ENST00000517919.6 [Q06455-1] ENST00000436581.7 ENST00000518844.5 [Q06455-2] ENST00000520556.5 ENST00000519847.6 E5RHJ8 ENST00000521897.5 ENST00000517919.6 W8FSQ8 Q71VC3 W8FSP9 ENST00000519847.6 [Q06455-1] E7EQW7 E5RFQ3 W8FP49 W8FP62 E7EQW3 ENST00000422361.6 [Q06455-4] ENST00000519422.5 E5RH72 E5RJB3 ENST00000522163.6 W8FW28 ENST00000518823.5 E5RH30 ENST00000360348.6 [Q06455-4] E7EQI9 ENST00000521553.5 ENST00000520974.5 W8FK92 ENST00000520724.5 [Q06455-3] ENST00000524215.5 ENST00000518361.1 W8FW32 ENST00000518954.6 H0YC25 ENST00000523629.6 [Q06455-1] E7EWJ9 E7EX23 E5RK76 H0YBA6 E7ESA9 ENST00000520428.5 W8FSQ5 E7ERJ9 ENST00000518992.5 ENST00000518832.2 ENST00000517792.5 ENST00000521319.5 E5RI38 E7EQJ1 ENST00000521733.5 W8FK78 ENST00000519061.5 ENST00000521375.5 E7EQ59 Q06455 W8FSQ2 ENST00000522467.5 W8FW37 ENST00000519577.5 E7ETA8 H0YC43 E5RJE7 ENST00000521751.5 ENST00000520978.5 ENST00000518317.6 ENST00000523168.5 ENST00000521054.5 W8FP57 ENST00000520583.5 ENST00000518317.6 [Q06455-2] A0A0A0MSU1 ENST00000518954.6 [Q06455-1] E5RG85 A0A1B0GX92 E7ESL1 |