ZNF488 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZNF488 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZNF488 at tissue level.

III. Associated gene sets

GO_0014003Biological processoligodendrocyte development
GO_0031643Biological processpositive regulation of myelination
GO_0048714Biological processpositive regulation of oligodendrocyte differentiation
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZNF488
Protein nameZinc finger protein 488
Synonyms
DescriptionFUNCTION: Transcriptional repressor. Plays a role in oligodendrocyte differentiation, together with OLIG2. Mediates Notch signaling-activated formation of oligodendrocyte precursors. Promotes differentiation of adult neural stem progenitor cells (NSPCs) into mature oligodendrocytes and contributes to remyelination following nerve injury. .

AccessionsENST00000585316.3 [Q96MN9-1]
ENST00000591025.1 [Q96MN9-2]
Q96MN9