ZBTB16 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051138Biological processpositive regulation of NK T cell differentiation
GO_0045638Biological processnegative regulation of myeloid cell differentiation
GO_0016567Biological processprotein ubiquitination
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0008283Biological processcell population proliferation
GO_0030097Biological processhemopoiesis
GO_0035136Biological processforelimb morphogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0042733Biological processembryonic digit morphogenesis
GO_0032332Biological processpositive regulation of chondrocyte differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0035116Biological processembryonic hindlimb morphogenesis
GO_0009880Biological processembryonic pattern specification
GO_0001823Biological processmesonephros development
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0030099Biological processmyeloid cell differentiation
GO_0034504Biological processprotein localization to nucleus
GO_0045600Biological processpositive regulation of fat cell differentiation
GO_0048133Biological processmale germ-line stem cell asymmetric division
GO_0009952Biological processanterior/posterior pattern specification
GO_0007417Biological processcentral nervous system development
GO_0006915Biological processapoptotic process
GO_0043065Biological processpositive regulation of apoptotic process
GO_0045778Biological processpositive regulation of ossification
GO_0051216Biological processcartilage development
GO_0043931Biological processossification involved in bone maturation
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0061036Biological processpositive regulation of cartilage development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0016607Cellular componentnuclear speck
GO_0032991Cellular componentprotein-containing complex
GO_0017053Cellular componenttranscription repressor complex
GO_0016604Cellular componentnuclear body
GO_0005829Cellular componentcytosol
GO_0016605Cellular componentPML body
GO_0001673Cellular componentmale germ cell nucleus
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0042803Molecular functionprotein homodimerization activity
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0019904Molecular functionprotein domain specific binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0031703Molecular functiontype 2 angiotensin receptor binding
GO_0001222Molecular functiontranscription corepressor binding
GO_0042802Molecular functionidentical protein binding
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameZBTB16
Protein nameZinc finger and BTB domain containing 16 isoform 1 (Zinc finger and BTB domain containing 16, isoform CRA_a)
Zinc finger and BTB domain containing 16
Zinc finger and BTB domain-containing protein 16 (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145) (Zinc finger protein PLZF)
SynonymsPLZF
ZNF145
hCG_38015
DescriptionFUNCTION: Acts as a transcriptional repressor . Transcriptional repression may be mediated through recruitment of histone deacetylases to target promoters . May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins . .

AccessionsENST00000683318.1 [Q05516-1]
ENST00000684612.1
A0A804HJ45
F5H6C3
Q05516
ENST00000335953.9 [Q05516-1]
A0A804HIC1
ENST00000684295.1 [Q05516-1]
ENST00000682971.1 [Q05516-1]
ENST00000682697.1 [Q05516-1]
ENST00000682810.1
ENST00000539918.5
ENST00000392996.2 [Q05516-1]
A0A024R3C6
ENST00000544220.1
ENST00000683233.1
A0A0S2Z4J5
ENST00000683554.1 [Q05516-1]
H0YGW2
ENST00000682278.1 [Q05516-1]