Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 33 studies | 49% ± 20% | |
fibroblast | 29 studies | 42% ± 23% | |
natural killer cell | 27 studies | 25% ± 8% | |
smooth muscle cell | 25 studies | 37% ± 16% | |
pericyte | 23 studies | 40% ± 17% | |
astrocyte | 16 studies | 40% ± 22% | |
oligodendrocyte | 13 studies | 45% ± 19% | |
CD16-positive, CD56-dim natural killer cell, human | 11 studies | 29% ± 12% | |
capillary endothelial cell | 11 studies | 46% ± 16% | |
CD16-negative, CD56-bright natural killer cell, human | 11 studies | 33% ± 17% | |
GABAergic neuron | 10 studies | 50% ± 23% | |
oligodendrocyte precursor cell | 10 studies | 46% ± 19% | |
endothelial cell of artery | 10 studies | 37% ± 19% | |
adipocyte | 10 studies | 67% ± 19% | |
glutamatergic neuron | 9 studies | 55% ± 28% | |
mucosal invariant T cell | 9 studies | 33% ± 10% | |
macrophage | 9 studies | 34% ± 17% | |
type I pneumocyte | 8 studies | 38% ± 15% | |
endothelial cell of vascular tree | 8 studies | 46% ± 22% | |
endothelial cell of lymphatic vessel | 7 studies | 35% ± 21% | |
myofibroblast cell | 7 studies | 35% ± 16% | |
vein endothelial cell | 7 studies | 40% ± 27% | |
mast cell | 7 studies | 28% ± 11% | |
T cell | 7 studies | 22% ± 6% | |
microglial cell | 7 studies | 48% ± 17% | |
mature NK T cell | 6 studies | 33% ± 10% | |
cardiac muscle cell | 6 studies | 57% ± 23% | |
mesothelial cell | 6 studies | 50% ± 30% | |
innate lymphoid cell | 6 studies | 29% ± 13% | |
adventitial cell | 5 studies | 37% ± 19% | |
basal cell | 5 studies | 36% ± 15% | |
club cell | 5 studies | 34% ± 8% | |
type II pneumocyte | 5 studies | 46% ± 13% | |
gamma-delta T cell | 5 studies | 28% ± 12% | |
interneuron | 5 studies | 58% ± 30% | |
connective tissue cell | 4 studies | 36% ± 17% | |
cholangiocyte | 4 studies | 66% ± 11% | |
hepatocyte | 4 studies | 75% ± 23% | |
naive B cell | 4 studies | 22% ± 3% | |
B cell | 4 studies | 22% ± 9% | |
epithelial cell | 4 studies | 43% ± 17% | |
muscle cell | 4 studies | 63% ± 21% | |
ciliated cell | 4 studies | 32% ± 10% | |
monocyte | 4 studies | 24% ± 3% | |
myoepithelial cell | 4 studies | 38% ± 18% | |
hepatic stellate cell | 3 studies | 67% ± 5% | |
glomerular endothelial cell | 3 studies | 60% ± 17% | |
neuron | 3 studies | 43% ± 15% | |
GABAergic interneuron | 3 studies | 41% ± 17% | |
hematopoietic stem cell | 3 studies | 24% ± 6% | |
dendritic cell | 3 studies | 21% ± 1% | |
mononuclear phagocyte | 3 studies | 41% ± 21% | |
non-classical monocyte | 3 studies | 20% ± 3% | |
myeloid cell | 3 studies | 45% ± 1% | |
ependymal cell | 3 studies | 44% ± 22% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 45% ± 5% | |
group 3 innate lymphoid cell | 3 studies | 40% ± 9% | |
Schwann cell | 3 studies | 44% ± 17% | |
epithelial cell of proximal tubule | 3 studies | 49% ± 24% | |
kidney loop of Henle epithelial cell | 3 studies | 44% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 80% | 1894.04 | 195 / 245 | 99% | 30.80 | 497 / 502 |
thymus | 89% | 2523.10 | 583 / 653 | 83% | 13.19 | 503 / 605 |
adrenal gland | 76% | 1032.66 | 195 / 258 | 83% | 13.98 | 191 / 230 |
pancreas | 76% | 1186.25 | 248 / 328 | 66% | 9.72 | 118 / 178 |
brain | 37% | 423.78 | 965 / 2642 | 97% | 35.54 | 681 / 705 |
breast | 91% | 3954.84 | 419 / 459 | 33% | 3.74 | 368 / 1118 |
liver | 58% | 788.46 | 130 / 226 | 60% | 6.53 | 242 / 406 |
kidney | 42% | 634.04 | 37 / 89 | 73% | 13.21 | 657 / 901 |
lung | 85% | 3243.03 | 489 / 578 | 29% | 3.59 | 338 / 1155 |
ovary | 84% | 2917.10 | 151 / 180 | 20% | 1.77 | 85 / 430 |
muscle | 100% | 5645.35 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 98% | 6349.80 | 1312 / 1335 | 0% | 0 | 0 / 0 |
uterus | 86% | 3454.15 | 147 / 170 | 9% | 1.48 | 43 / 459 |
esophagus | 70% | 2457.77 | 1007 / 1445 | 25% | 2.61 | 46 / 183 |
adipose | 94% | 4436.14 | 1130 / 1204 | 0% | 0 | 0 / 0 |
stomach | 78% | 1774.04 | 281 / 359 | 15% | 1.46 | 42 / 286 |
bladder | 81% | 3371.00 | 17 / 21 | 11% | 0.89 | 57 / 504 |
intestine | 80% | 2035.34 | 776 / 966 | 10% | 1.05 | 53 / 527 |
skin | 86% | 2965.63 | 1558 / 1809 | 4% | 0.25 | 19 / 472 |
heart | 73% | 1606.09 | 626 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 57% | 5.21 | 46 / 80 |
spleen | 51% | 577.39 | 124 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 38% | 547.78 | 350 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 4% | 0.54 | 2 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051138 | Biological process | positive regulation of NK T cell differentiation |
GO_0045638 | Biological process | negative regulation of myeloid cell differentiation |
GO_0016567 | Biological process | protein ubiquitination |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0008283 | Biological process | cell population proliferation |
GO_0030097 | Biological process | hemopoiesis |
GO_0035136 | Biological process | forelimb morphogenesis |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0042733 | Biological process | embryonic digit morphogenesis |
GO_0032332 | Biological process | positive regulation of chondrocyte differentiation |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0035116 | Biological process | embryonic hindlimb morphogenesis |
GO_0009880 | Biological process | embryonic pattern specification |
GO_0001823 | Biological process | mesonephros development |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0030099 | Biological process | myeloid cell differentiation |
GO_0034504 | Biological process | protein localization to nucleus |
GO_0045600 | Biological process | positive regulation of fat cell differentiation |
GO_0048133 | Biological process | male germ-line stem cell asymmetric division |
GO_0009952 | Biological process | anterior/posterior pattern specification |
GO_0007417 | Biological process | central nervous system development |
GO_0006915 | Biological process | apoptotic process |
GO_0043065 | Biological process | positive regulation of apoptotic process |
GO_0045778 | Biological process | positive regulation of ossification |
GO_0051216 | Biological process | cartilage development |
GO_0043931 | Biological process | ossification involved in bone maturation |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0061036 | Biological process | positive regulation of cartilage development |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0016607 | Cellular component | nuclear speck |
GO_0032991 | Cellular component | protein-containing complex |
GO_0017053 | Cellular component | transcription repressor complex |
GO_0016604 | Cellular component | nuclear body |
GO_0005829 | Cellular component | cytosol |
GO_0016605 | Cellular component | PML body |
GO_0001673 | Cellular component | male germ cell nucleus |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
GO_0031703 | Molecular function | type 2 angiotensin receptor binding |
GO_0001222 | Molecular function | transcription corepressor binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ZBTB16 |
Protein name | Zinc finger and BTB domain containing 16 isoform 1 (Zinc finger and BTB domain containing 16, isoform CRA_a) Zinc finger and BTB domain containing 16 Zinc finger and BTB domain-containing protein 16 (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145) (Zinc finger protein PLZF) |
Synonyms | PLZF ZNF145 hCG_38015 |
Description | FUNCTION: Acts as a transcriptional repressor . Transcriptional repression may be mediated through recruitment of histone deacetylases to target promoters . May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins . . |
Accessions | ENST00000683318.1 [Q05516-1] ENST00000684612.1 A0A804HJ45 F5H6C3 Q05516 ENST00000335953.9 [Q05516-1] A0A804HIC1 ENST00000684295.1 [Q05516-1] ENST00000682971.1 [Q05516-1] ENST00000682697.1 [Q05516-1] ENST00000682810.1 ENST00000539918.5 ENST00000392996.2 [Q05516-1] A0A024R3C6 ENST00000544220.1 ENST00000683233.1 A0A0S2Z4J5 ENST00000683554.1 [Q05516-1] H0YGW2 ENST00000682278.1 [Q05516-1] |