THAP7 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of THAP7 at tissue level.

III. Associated gene sets

GO_0006325Biological processchromatin organization
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006355Biological processregulation of DNA-templated transcription
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0000785Cellular componentchromatin
GO_0031965Cellular componentnuclear membrane
GO_0005634Cellular componentnucleus
GO_0035064Molecular functionmethylated histone binding
GO_0003677Molecular functionDNA binding
GO_0042393Molecular functionhistone binding
GO_0070577Molecular functionlysine-acetylated histone binding
GO_0001222Molecular functiontranscription corepressor binding
GO_0042802Molecular functionidentical protein binding
GO_0106153Molecular functionphosphorylated histone binding
GO_0140566Molecular functionhistone reader activity
GO_0046872Molecular functionmetal ion binding
GO_0140296Molecular functiongeneral transcription initiation factor binding
GO_0005515Molecular functionprotein binding
GO_0070742Molecular functionC2H2 zinc finger domain binding
GO_0042826Molecular functionhistone deacetylase binding

IV. Literature review

[source]
Gene nameTHAP7
Protein nameTHAP domain-containing protein 7
Synonyms
DescriptionFUNCTION: Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors. .

AccessionsENST00000215742.9
Q9BT49
ENST00000399133.2