SOX8 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	11 studies	26% ± 6%	Explore
oligodendrocyte precursor cell	11 studies	39% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	4 studies	20% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	5925.80	2631 / 2642	99%	529.53	701 / 705
skin	44%	566.67	801 / 1809	71%	29.24	335 / 472
eye	0%	0	0 / 0	95%	33.45	76 / 80
intestine	31%	278.05	302 / 966	20%	2.42	107 / 527
pancreas	2%	13.72	6 / 328	34%	3.94	61 / 178
breast	21%	193.92	95 / 459	11%	4.58	128 / 1118
prostate	11%	89.26	27 / 245	19%	1.22	96 / 502
blood vessel	30%	350.48	401 / 1335	0%	0	0 / 0
esophagus	16%	140.70	227 / 1445	11%	1.57	21 / 183
heart	24%	238.17	205 / 861	0%	0	0 / 0
stomach	4%	34.81	15 / 359	16%	3.78	46 / 286
bladder	14%	104.86	3 / 21	6%	0.63	30 / 504
lymph node	0%	0	0 / 0	17%	1.97	5 / 29
thymus	1%	9.75	9 / 653	15%	1.30	93 / 605
adrenal gland	1%	4.92	2 / 258	15%	1.90	34 / 230
kidney	1%	6.06	1 / 89	14%	1.80	128 / 901
tonsil	0%	0	0 / 0	13%	5.19	6 / 45
uterus	2%	16.14	4 / 170	8%	2.52	35 / 459
lung	0%	3.80	2 / 578	7%	0.72	79 / 1155
adipose	6%	63.91	77 / 1204	0%	0	0 / 0
spleen	3%	24.19	8 / 241	0%	0	0 / 0
liver	0%	7.72	1 / 226	2%	0.29	8 / 406
muscle	1%	11.04	11 / 803	0%	0	0 / 0
ovary	1%	3.29	1 / 180	1%	0.05	3 / 430
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0048484	Biological process	enteric nervous system development
GO_0007283	Biological process	spermatogenesis
GO_0002009	Biological process	morphogenesis of an epithelium
GO_0033690	Biological process	positive regulation of osteoblast proliferation
GO_0001701	Biological process	in utero embryonic development
GO_0060009	Biological process	Sertoli cell development
GO_0001755	Biological process	neural crest cell migration
GO_0001649	Biological process	osteoblast differentiation
GO_0045662	Biological process	negative regulation of myoblast differentiation
GO_0060221	Biological process	retinal rod cell differentiation
GO_0007165	Biological process	signal transduction
GO_0010628	Biological process	positive regulation of gene expression
GO_0060041	Biological process	retina development in camera-type eye
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0014032	Biological process	neural crest cell development
GO_0046533	Biological process	negative regulation of photoreceptor cell differentiation
GO_0072034	Biological process	renal vesicle induction
GO_0010817	Biological process	regulation of hormone levels
GO_0045165	Biological process	cell fate commitment
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0072289	Biological process	metanephric nephron tubule formation
GO_0007422	Biological process	peripheral nervous system development
GO_0014015	Biological process	positive regulation of gliogenesis
GO_0090190	Biological process	positive regulation of branching involved in ureteric bud morphogenesis
GO_0048709	Biological process	oligodendrocyte differentiation
GO_0060018	Biological process	astrocyte fate commitment
GO_0060612	Biological process	adipose tissue development
GO_0008584	Biological process	male gonad development
GO_0035914	Biological process	skeletal muscle cell differentiation
GO_0072197	Biological process	ureter morphogenesis
GO_0048469	Biological process	cell maturation
GO_0090184	Biological process	positive regulation of kidney development
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0061138	Biological process	morphogenesis of a branching epithelium
GO_0045444	Biological process	fat cell differentiation
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005737	Cellular component	cytoplasm
GO_0000785	Cellular component	chromatin
GO_0005667	Cellular component	transcription regulator complex
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0140297	Molecular function	DNA-binding transcription factor binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding

Gene name	SOX8
Protein name	Transcription factor SOX-8
Synonyms
Description	FUNCTION: Transcription factor that may play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (By similarity). .
Accessions	P57073 ENST00000293894.4

SOX8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review