CTBP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	32 studies	37% ± 17%	Explore
pericyte	24 studies	32% ± 16%	Explore
smooth muscle cell	21 studies	27% ± 9%	Explore
fibroblast	18 studies	28% ± 11%	Explore
ciliated cell	16 studies	35% ± 15%	Explore
natural killer cell	15 studies	23% ± 8%	Explore
astrocyte	14 studies	42% ± 17%	Explore
macrophage	12 studies	38% ± 19%	Explore
microglial cell	12 studies	49% ± 15%	Explore
oligodendrocyte	12 studies	31% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	24% ± 7%	Explore
epithelial cell	11 studies	42% ± 23%	Explore
oligodendrocyte precursor cell	10 studies	32% ± 13%	Explore
basal cell	10 studies	34% ± 19%	Explore
GABAergic neuron	8 studies	34% ± 17%	Explore
endothelial cell of artery	8 studies	19% ± 4%	Explore
amacrine cell	8 studies	39% ± 12%	Explore
myeloid cell	8 studies	30% ± 9%	Explore
mast cell	8 studies	24% ± 6%	Explore
non-classical monocyte	7 studies	26% ± 13%	Explore
glutamatergic neuron	7 studies	39% ± 18%	Explore
capillary endothelial cell	7 studies	28% ± 12%	Explore
neuron	7 studies	41% ± 18%	Explore
adipocyte	7 studies	19% ± 4%	Explore
endothelial cell of lymphatic vessel	7 studies	34% ± 13%	Explore
interneuron	6 studies	43% ± 18%	Explore
club cell	6 studies	34% ± 11%	Explore
retina horizontal cell	6 studies	45% ± 8%	Explore
retinal cone cell	6 studies	45% ± 16%	Explore
retinal rod cell	6 studies	25% ± 6%	Explore
Mueller cell	6 studies	30% ± 10%	Explore
endothelial cell of vascular tree	6 studies	30% ± 18%	Explore
type I pneumocyte	6 studies	28% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	21% ± 4%	Explore
retinal bipolar neuron	5 studies	35% ± 11%	Explore
dendritic cell	5 studies	30% ± 8%	Explore
respiratory goblet cell	5 studies	39% ± 15%	Explore
type II pneumocyte	5 studies	24% ± 8%	Explore
monocyte	5 studies	35% ± 11%	Explore
goblet cell	5 studies	42% ± 27%	Explore
classical monocyte	4 studies	26% ± 8%	Explore
abnormal cell	4 studies	20% ± 4%	Explore
granule cell	4 studies	36% ± 6%	Explore
brush cell	4 studies	30% ± 7%	Explore
retinal pigment epithelial cell	4 studies	39% ± 10%	Explore
cardiac muscle cell	4 studies	29% ± 3%	Explore
vein endothelial cell	4 studies	34% ± 20%	Explore
lymphocyte	4 studies	21% ± 6%	Explore
muscle cell	4 studies	30% ± 13%	Explore
myofibroblast cell	4 studies	31% ± 13%	Explore
conventional dendritic cell	3 studies	26% ± 13%	Explore
hematopoietic precursor cell	3 studies	30% ± 9%	Explore
glomerular endothelial cell	3 studies	21% ± 4%	Explore
neural crest cell	3 studies	22% ± 4%	Explore
glial cell	3 studies	37% ± 15%	Explore
progenitor cell	3 studies	38% ± 5%	Explore
mononuclear phagocyte	3 studies	28% ± 8%	Explore
GABAergic amacrine cell	3 studies	59% ± 4%	Explore
OFF-bipolar cell	3 studies	37% ± 10%	Explore
ON-bipolar cell	3 studies	36% ± 10%	Explore
glycinergic amacrine cell	3 studies	27% ± 3%	Explore
rod bipolar cell	3 studies	39% ± 5%	Explore
secretory cell	3 studies	24% ± 6%	Explore
cholangiocyte	3 studies	56% ± 14%	Explore
neural progenitor cell	3 studies	38% ± 13%	Explore
connective tissue cell	3 studies	31% ± 5%	Explore
ependymal cell	3 studies	45% ± 19%	Explore
enteroendocrine cell	3 studies	23% ± 6%	Explore
intestinal crypt stem cell	3 studies	20% ± 3%	Explore
alveolar macrophage	3 studies	42% ± 15%	Explore
transit amplifying cell	3 studies	44% ± 34%	Explore
mesothelial cell	3 studies	30% ± 8%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	28% ± 8%	Explore
mucus secreting cell	3 studies	41% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	13 studies	36% ± 13%	Explore
lung	10 studies	26% ± 9%	Explore
eye	9 studies	33% ± 12%	Explore
heart	4 studies	26% ± 5%	Explore
intestine	4 studies	21% ± 6%	Explore
peripheral blood	3 studies	21% ± 5%	Explore
adipose	3 studies	31% ± 6%	Explore
liver	3 studies	30% ± 11%	Explore
kidney	3 studies	30% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	5717.35	245 / 245	100%	29.44	502 / 502
ovary	100%	5369.67	180 / 180	100%	29.98	428 / 430
esophagus	100%	4020.92	1445 / 1445	99%	27.65	182 / 183
intestine	100%	4209.56	966 / 966	99%	28.95	524 / 527
lung	100%	4355.76	578 / 578	99%	20.68	1148 / 1155
breast	100%	4367.68	459 / 459	99%	33.63	1107 / 1118
brain	99%	2412.33	2626 / 2642	100%	15.53	702 / 705
stomach	100%	3945.91	359 / 359	99%	28.13	283 / 286
kidney	100%	3622.28	89 / 89	98%	20.44	886 / 901
pancreas	100%	2353.86	328 / 328	98%	17.86	174 / 178
uterus	100%	6588.06	170 / 170	98%	22.81	448 / 459
skin	100%	2781.43	1805 / 1809	96%	18.79	452 / 472
thymus	100%	6384.55	653 / 653	95%	30.21	572 / 605
bladder	100%	3952.71	21 / 21	93%	17.16	471 / 504
adrenal gland	100%	3078.53	258 / 258	92%	10.69	211 / 230
adipose	100%	3504.26	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5281.03	1335 / 1335	0%	0	0 / 0
spleen	100%	2879.58	241 / 241	0%	0	0 / 0
heart	98%	1718.44	847 / 861	0%	0	0 / 0
muscle	98%	1617.21	786 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	14.18	44 / 45
eye	0%	0	0 / 0	89%	11.49	71 / 80
peripheral blood	72%	1296.55	672 / 929	0%	0	0 / 0
liver	11%	102.03	25 / 226	18%	2.94	75 / 406
lymph node	0%	0	0 / 0	7%	0.37	2 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0048386	Biological process	positive regulation of retinoic acid receptor signaling pathway
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0019079	Biological process	viral genome replication
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0050872	Biological process	white fat cell differentiation
GO_0017053	Cellular component	transcription repressor complex
GO_0045202	Cellular component	synapse
GO_0005634	Cellular component	nucleus
GO_0140297	Molecular function	DNA-binding transcription factor binding
GO_0044877	Molecular function	protein-containing complex binding
GO_0001221	Molecular function	transcription coregulator binding
GO_0051287	Molecular function	NAD binding
GO_0019901	Molecular function	protein kinase binding
GO_0003714	Molecular function	transcription corepressor activity
GO_0001222	Molecular function	transcription corepressor binding
GO_0003713	Molecular function	transcription coactivator activity
GO_0005515	Molecular function	protein binding
GO_0016616	Molecular function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

IV. Literature review

[source]

Gene name	CTBP2
Protein name	C-terminal-binding protein 2 (CtBP2) C-terminal binding protein 2
Synonyms
Description	FUNCTION: Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). .; FUNCTION: Isoform 2 probably acts as a scaffold for specialized synapses.
Accessions	ENST00000309035.11 [P56545-2] ENST00000411419.7 [P56545-1] ENST00000531469.5 [P56545-1] A0A087WYL1 P56545 ENST00000395705.3 ENST00000494626.6 [P56545-1] ENST00000337195.10 [P56545-1] ENST00000334808.10 [P56545-3]

CTBP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review