PHC2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007283Biological processspermatogenesis
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0031519Cellular componentPcG protein complex
GO_0000792Cellular componentheterochromatin
GO_0035102Cellular componentPRC1 complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0042393Molecular functionhistone binding
GO_0003682Molecular functionchromatin binding

IV. Literature review

[source]
Gene namePHC2
Protein namePHC2 protein
Polyhomeotic homolog 2
Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2)
SynonymsPH2
EDR2
DescriptionFUNCTION: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

AccessionsENST00000485928.5
A0A8I5KY19
A0A994J5J9
A0A8I5KPD5
ENST00000486897.5
ENST00000373418.7 [Q8IXK0-2]
ENST00000683057.1 [Q8IXK0-5]
Q8IXK0
ENST00000493483.5
ENST00000706360.1
B7ZLY0
ENST00000373422.8
A0A0A0MSI2
ENST00000467894.5
ENST00000257118.5 [Q8IXK0-1]
ENST00000431992.6