Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 7 studies | 39% ± 24% | |
GABAergic neuron | 6 studies | 40% ± 19% | |
endothelial cell | 5 studies | 26% ± 10% | |
epithelial cell | 5 studies | 27% ± 6% | |
oligodendrocyte precursor cell | 5 studies | 31% ± 13% | |
interneuron | 5 studies | 37% ± 22% | |
CD4-positive, alpha-beta T cell | 4 studies | 19% ± 5% | |
astrocyte | 4 studies | 27% ± 7% | |
oligodendrocyte | 4 studies | 24% ± 3% | |
microglial cell | 3 studies | 18% ± 0% | |
ciliated cell | 3 studies | 23% ± 5% | |
neuron | 3 studies | 29% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 813.30 | 1444 / 1445 | 100% | 7.44 | 183 / 183 |
brain | 100% | 1275.90 | 2640 / 2642 | 100% | 9.54 | 704 / 705 |
prostate | 100% | 1019.35 | 245 / 245 | 99% | 6.50 | 499 / 502 |
breast | 100% | 851.03 | 459 / 459 | 99% | 7.29 | 1110 / 1118 |
uterus | 100% | 1036.09 | 170 / 170 | 98% | 7.99 | 451 / 459 |
bladder | 100% | 783.00 | 21 / 21 | 98% | 6.55 | 493 / 504 |
pancreas | 100% | 705.70 | 328 / 328 | 98% | 4.82 | 174 / 178 |
intestine | 100% | 811.13 | 966 / 966 | 97% | 7.11 | 512 / 527 |
thymus | 100% | 1095.82 | 653 / 653 | 97% | 6.02 | 587 / 605 |
stomach | 99% | 576.11 | 357 / 359 | 98% | 6.51 | 279 / 286 |
lung | 98% | 558.53 | 569 / 578 | 98% | 6.53 | 1134 / 1155 |
ovary | 100% | 1061.09 | 180 / 180 | 95% | 5.98 | 410 / 430 |
adrenal gland | 100% | 682.43 | 258 / 258 | 91% | 6.05 | 209 / 230 |
skin | 100% | 985.86 | 1809 / 1809 | 89% | 5.70 | 419 / 472 |
kidney | 100% | 666.75 | 89 / 89 | 86% | 3.87 | 777 / 901 |
liver | 100% | 506.08 | 225 / 226 | 68% | 2.63 | 277 / 406 |
adipose | 100% | 649.57 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 6.35 | 29 / 29 |
muscle | 100% | 1103.17 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1268.75 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 7.09 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.89 | 1 / 1 |
blood vessel | 100% | 570.24 | 1330 / 1335 | 0% | 0 | 0 / 0 |
heart | 97% | 676.51 | 839 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 68% | 3.88 | 54 / 80 |
peripheral blood | 54% | 379.67 | 501 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0043029 | Biological process | T cell homeostasis |
GO_0070245 | Biological process | positive regulation of thymocyte apoptotic process |
GO_0042795 | Biological process | snRNA transcription by RNA polymerase II |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0033085 | Biological process | negative regulation of T cell differentiation in thymus |
GO_0042796 | Biological process | snRNA transcription by RNA polymerase III |
GO_0045945 | Biological process | positive regulation of transcription by RNA polymerase III |
GO_0046677 | Biological process | response to antibiotic |
GO_0006915 | Biological process | apoptotic process |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0035363 | Cellular component | histone locus body |
GO_0008023 | Cellular component | transcription elongation factor complex |
GO_0000791 | Cellular component | euchromatin |
GO_0005654 | Cellular component | nucleoplasm |
GO_0016604 | Cellular component | nuclear body |
GO_0015030 | Cellular component | Cajal body |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
GO_0046872 | Molecular function | metal ion binding |
GO_0003723 | Molecular function | RNA binding |
GO_0001162 | Molecular function | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ZC3H8 |
Protein name | Zinc finger CCCH domain-containing protein 8 |
Synonyms | ZC3HDC8 |
Description | FUNCTION: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III . Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. . |
Accessions | Q8N5P1 ENST00000409573.7 |