CREBZF | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	8 studies	22% ± 5%	Explore
astrocyte	7 studies	32% ± 12%	Explore
oligodendrocyte	7 studies	34% ± 11%	Explore
B cell	6 studies	23% ± 5%	Explore
natural killer cell	6 studies	22% ± 6%	Explore
endothelial cell	6 studies	24% ± 4%	Explore
epithelial cell	5 studies	35% ± 11%	Explore
retinal rod cell	5 studies	16% ± 0%	Explore
oligodendrocyte precursor cell	5 studies	33% ± 12%	Explore
smooth muscle cell	5 studies	17% ± 1%	Explore
retinal cone cell	4 studies	25% ± 6%	Explore
adipocyte	4 studies	23% ± 6%	Explore
GABAergic neuron	4 studies	46% ± 14%	Explore
interneuron	4 studies	37% ± 23%	Explore
T cell	3 studies	18% ± 2%	Explore
endothelial cell of lymphatic vessel	3 studies	18% ± 2%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	23% ± 4%	Explore
CD4-positive, alpha-beta T cell	3 studies	25% ± 6%	Explore
CD8-positive, alpha-beta T cell	3 studies	24% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	22% ± 4%	Explore
mature NK T cell	3 studies	20% ± 4%	Explore
retinal bipolar neuron	3 studies	24% ± 1%	Explore
plasma cell	3 studies	29% ± 7%	Explore
retina horizontal cell	3 studies	26% ± 3%	Explore
ciliated cell	3 studies	27% ± 2%	Explore
lymphocyte	3 studies	22% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	21% ± 5%	Explore
gamma-delta T cell	3 studies	28% ± 4%	Explore
naive B cell	3 studies	17% ± 2%	Explore
glutamatergic neuron	3 studies	64% ± 11%	Explore
microglial cell	3 studies	20% ± 2%	Explore
abnormal cell	3 studies	21% ± 4%	Explore
myofibroblast cell	3 studies	23% ± 5%	Explore
pericyte	3 studies	21% ± 4%	Explore
basal cell	3 studies	28% ± 9%	Explore
goblet cell	3 studies	28% ± 8%	Explore
transit amplifying cell	3 studies	30% ± 19%	Explore
neuron	3 studies	30% ± 9%	Explore
plasmacytoid dendritic cell	3 studies	18% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	6 studies	42% ± 19%	Explore
eye	5 studies	22% ± 6%	Explore
peripheral blood	3 studies	27% ± 8%	Explore
lung	3 studies	17% ± 1%	Explore
intestine	3 studies	20% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7011.75	1445 / 1445	100%	29.45	183 / 183
intestine	100%	8592.31	966 / 966	100%	27.91	526 / 527
breast	100%	9532.12	459 / 459	100%	32.99	1115 / 1118
lung	100%	8611.91	577 / 578	100%	30.19	1153 / 1155
stomach	100%	6917.16	359 / 359	100%	26.15	285 / 286
prostate	100%	8546.97	245 / 245	100%	32.03	500 / 502
bladder	100%	7788.29	21 / 21	99%	28.27	500 / 504
thymus	100%	11731.55	653 / 653	99%	29.74	599 / 605
pancreas	100%	5729.02	328 / 328	99%	28.55	176 / 178
uterus	100%	12419.82	170 / 170	98%	29.45	451 / 459
ovary	100%	12705.77	180 / 180	98%	20.76	422 / 430
kidney	100%	5511.42	89 / 89	98%	26.75	883 / 901
adrenal gland	100%	7283.52	258 / 258	97%	22.13	224 / 230
brain	97%	4935.83	2567 / 2642	100%	40.19	705 / 705
skin	100%	6777.77	1808 / 1809	91%	21.24	431 / 472
liver	100%	3716.83	226 / 226	87%	13.16	354 / 406
adipose	100%	7665.39	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	22.77	29 / 29
spleen	100%	9074.11	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	12.13	1 / 1
blood vessel	100%	8701.42	1334 / 1335	0%	0	0 / 0
muscle	99%	3551.57	795 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	18.32	44 / 45
heart	97%	3564.45	832 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	73%	13.45	58 / 80
peripheral blood	44%	2213.58	407 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0009615	Biological process	response to virus
GO_0045814	Biological process	negative regulation of gene expression, epigenetic
GO_0036500	Biological process	ATF6-mediated unfolded protein response
GO_0051090	Biological process	regulation of DNA-binding transcription factor activity
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0140467	Biological process	integrated stress response signaling
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0090575	Cellular component	RNA polymerase II transcription regulator complex
GO_0005739	Cellular component	mitochondrion
GO_0005654	Cellular component	nucleoplasm
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CREBZF
Protein name	CREB/ATF bZIP transcription factor CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei)
Synonyms	ZF
Description	FUNCTION: Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells. .
Accessions	ENST00000490820.2 ENST00000525639.1 H0YDC7 J3KN20 E9PIM0 ENST00000682836.1 ENST00000527529.6 ENST00000527447.2 ENST00000260058.9 Q9NS37

CREBZF report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review