Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 23% ± 4% |
Insufficient scRNA-seq data for expression of ZNF219 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 6404.69 | 1445 / 1445 | 100% | 21.40 | 183 / 183 |
| thymus | 100% | 4351.55 | 651 / 653 | 99% | 28.21 | 600 / 605 |
| uterus | 100% | 4875.30 | 170 / 170 | 98% | 21.44 | 450 / 459 |
| ovary | 100% | 3525.46 | 180 / 180 | 98% | 28.17 | 421 / 430 |
| intestine | 100% | 7410.40 | 966 / 966 | 97% | 18.18 | 509 / 527 |
| bladder | 100% | 5460.24 | 21 / 21 | 96% | 18.80 | 485 / 504 |
| brain | 96% | 2775.77 | 2538 / 2642 | 100% | 25.26 | 703 / 705 |
| adrenal gland | 100% | 8851.50 | 258 / 258 | 96% | 19.48 | 220 / 230 |
| stomach | 100% | 3437.10 | 359 / 359 | 95% | 18.66 | 273 / 286 |
| skin | 99% | 4301.62 | 1784 / 1809 | 96% | 17.63 | 451 / 472 |
| prostate | 100% | 4907.21 | 245 / 245 | 93% | 10.66 | 467 / 502 |
| lung | 99% | 4082.26 | 575 / 578 | 91% | 14.13 | 1046 / 1155 |
| pancreas | 96% | 1703.57 | 316 / 328 | 93% | 13.33 | 165 / 178 |
| kidney | 94% | 1919.31 | 84 / 89 | 93% | 12.95 | 842 / 901 |
| breast | 100% | 4607.90 | 458 / 459 | 83% | 10.33 | 924 / 1118 |
| liver | 73% | 969.70 | 165 / 226 | 90% | 11.10 | 367 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 13.88 | 80 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 20.01 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.70 | 1 / 1 |
| adipose | 100% | 4940.10 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 4407.43 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 97% | 2377.72 | 782 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 3276.57 | 834 / 861 | 0% | 0 | 0 / 0 |
| spleen | 95% | 1536.80 | 229 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 55% | 3.05 | 16 / 29 |
| peripheral blood | 11% | 110.23 | 101 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032332 | Biological process | positive regulation of chondrocyte differentiation |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0060174 | Biological process | limb bud formation |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0004969 | Molecular function | histamine receptor activity |
| Gene name | ZNF219 |
| Protein name | Zinc finger protein 219 |
| Synonyms | |
| Description | FUNCTION: Transcriptional regulator . Recognizes and binds 2 copies of the core DNA sequence motif 5'-GGGGG-3' . Binds to the HMGN1 promoter and may repress HMGN1 expression . Regulates SNCA expression in primary cortical neurons . Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with SOX9 (By similarity). Plays a role in chondrocyte differentiation (By similarity). . |
| Accessions | ENST00000553296.1 ENST00000554478.5 G3V2Q8 G3V4M7 ENST00000554923.1 G3V2W3 ENST00000556174.5 G3V3F2 G3V2E3 Q9P2Y4 ENST00000555270.5 ENST00000553980.1 G3V452 ENST00000451119.6 G3V4T1 ENST00000360947.8 ENST00000555697.1 ENST00000421093.6 |