ZNF219 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZNF219 at tissue level.

III. Associated gene sets

GO_0032332Biological processpositive regulation of chondrocyte differentiation
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0060174Biological processlimb bud formation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0006355Biological processregulation of DNA-templated transcription
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0016020Cellular componentmembrane
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding
GO_0004969Molecular functionhistamine receptor activity

IV. Literature review

[source]
Gene nameZNF219
Protein nameZinc finger protein 219
Synonyms
DescriptionFUNCTION: Transcriptional regulator . Recognizes and binds 2 copies of the core DNA sequence motif 5'-GGGGG-3' . Binds to the HMGN1 promoter and may repress HMGN1 expression . Regulates SNCA expression in primary cortical neurons . Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with SOX9 (By similarity). Plays a role in chondrocyte differentiation (By similarity). .

AccessionsENST00000553296.1
ENST00000554478.5
G3V2Q8
G3V4M7
ENST00000554923.1
G3V2W3
ENST00000556174.5
G3V3F2
G3V2E3
Q9P2Y4
ENST00000555270.5
ENST00000553980.1
G3V452
ENST00000451119.6
G3V4T1
ENST00000360947.8
ENST00000555697.1
ENST00000421093.6