I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 26% ± 9% | |
| GABAergic neuron | 4 studies | 19% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 26% ± 9% | |
| GABAergic neuron | 4 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 713.71 | 1445 / 1445 | 99% | 6.23 | 182 / 183 |
| intestine | 100% | 682.52 | 966 / 966 | 99% | 5.25 | 523 / 527 |
| skin | 100% | 524.45 | 1805 / 1809 | 99% | 5.91 | 469 / 472 |
| pancreas | 100% | 403.41 | 328 / 328 | 99% | 5.20 | 176 / 178 |
| stomach | 100% | 643.55 | 359 / 359 | 99% | 7.45 | 282 / 286 |
| thymus | 100% | 901.79 | 653 / 653 | 98% | 4.55 | 593 / 605 |
| bladder | 100% | 396.38 | 21 / 21 | 98% | 8.83 | 492 / 504 |
| brain | 99% | 837.63 | 2619 / 2642 | 98% | 4.65 | 693 / 705 |
| prostate | 100% | 465.66 | 245 / 245 | 96% | 2.64 | 484 / 502 |
| lung | 99% | 636.80 | 575 / 578 | 97% | 5.33 | 1116 / 1155 |
| breast | 100% | 564.58 | 459 / 459 | 96% | 3.06 | 1072 / 1118 |
| uterus | 100% | 779.19 | 170 / 170 | 95% | 5.96 | 438 / 459 |
| ovary | 100% | 1120.29 | 180 / 180 | 94% | 4.00 | 405 / 430 |
| kidney | 100% | 516.07 | 89 / 89 | 94% | 3.14 | 847 / 901 |
| adrenal gland | 100% | 380.11 | 258 / 258 | 90% | 2.83 | 206 / 230 |
| liver | 100% | 326.94 | 226 / 226 | 81% | 3.02 | 330 / 406 |
| adipose | 100% | 663.53 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 3.45 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 4.15 | 29 / 29 |
| spleen | 100% | 847.79 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.79 | 1 / 1 |
| blood vessel | 99% | 390.95 | 1318 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 295.27 | 842 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 3.93 | 44 / 45 |
| muscle | 91% | 219.17 | 730 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 88% | 356.05 | 821 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0002682 | Biological process | regulation of immune system process |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0001817 | Biological process | regulation of cytokine production |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | HIC2 |
| Protein name | Hypermethylated in cancer 2 protein (Hic-2) (HIC1-related gene on chromosome 22 protein) (Hic-3) (Zinc finger and BTB domain-containing protein 30) |
| Synonyms | KIAA1020 ZBTB30 HRG22 |
| Description | FUNCTION: Transcriptional repressor. |
| Accessions | ENST00000443632.2 [Q96JB3-1] ENST00000407464.7 [Q96JB3-1] ENST00000407598.2 [Q96JB3-1] Q96JB3 |
